AJP - Heart Calcium Transients and Cell-Sarcomere
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 249: H1216-H1223, 1985;
0363-6135/85 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Heineman, F. W.
Right arrow Articles by Grayson, J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Heineman, F. W.
Right arrow Articles by Grayson, J.

AJP - Heart and Circulatory Physiology, Vol 249, Issue 6 1216-H1223, Copyright © 1985 by American Physiological Society

ARTICLES

Transmural distribution of intramyocardial pressure measured by micropipette technique

F. W. Heineman and J. Grayson

A technique is presented for measuring intramyocardial pressure (IMP) in beating hearts using the servo-nulling pressure transducer equipped with polyethylene micropipettes (ID less than 12 micron). The static and dynamic response characteristics of the system were tested in a pressurized, saline-filled container as well as in a pressurized, hollow, gelatin cylinder. The system was then used to measure IMP in vivo in the hearts of 12 dogs during stable cardiac performance and with aortic constriction. In vitro response characteristics were found to be satisfactory for accurate reproduction of cardiovascular waveforms. Peak systolic IMP was not found to exceed the simultaneously recorded left intraventricular pressure (LVP). Furthermore, the slope of the regression line relating the IMP to LVP during systole is linearly related (slope 0.98) to the depth of the micropipette tip in the ventricular wall, as normalized to total wall thickness. Diastolic IMP ranged between 1 +/- 1 (minimum during the cardiac cycle) and 4 +/- 2 mmHg (end diastolic) at associated LVP of 2 +/- 2 and 5 +/- 2 mmHg (mean +/- SD), respectively.


This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
D. Garcia, P. G. Camici, L.-G. Durand, K. Rajappan, E. Gaillard, O. E. Rimoldi, and P. Pibarot
Impairment of coronary flow reserve in aortic stenosis
J Appl Physiol, January 1, 2009; 106(1): 113 - 121.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
D. J. Duncker and R. J. Bache
Regulation of Coronary Blood Flow During Exercise
Physiol Rev, July 1, 2008; 88(3): 1009 - 1086.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
Y. Liu, W. Zhang, and G. S. Kassab
Effects of myocardial constraint on the passive mechanical behaviors of the coronary vessel wall
Am J Physiol Heart Circ Physiol, January 1, 2008; 294(1): H514 - H523.
[Abstract] [Full Text] [PDF]

Home page
 Physiol. Rev.Home page
N. Westerhof, C. Boer, R. R. Lamberts, and P. Sipkema
Cross-talk between cardiac muscle and coronary vasculature.
Physiol Rev, October 1, 2006; 86(4): 1263 - 1308.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
J. S. Choy and G. S. Kassab
A novel strategy for increasing wall thickness of coronary venules prior to retroperfusion
Am J Physiol Heart Circ Physiol, August 1, 2006; 291(2): H972 - H978.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
E. Toyota, Y. Ogasawara, O. Hiramatsu, H. Tachibana, F. Kajiya, S. Yamamori, and W. M. Chilian
Dynamics of flow velocities in endocardial and epicardial coronary arterioles
Am J Physiol Heart Circ Physiol, April 1, 2005; 288(4): H1598 - H1603.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
R. C. Marshall, P. Powers-Risius, B. W. Reutter, A. M. Schustz, C. Kuo, M. K. Huesman, and R. H. Huesman
Flow heterogeneity following global no-flow ischemia in isolated rabbit heart
Am J Physiol Heart Circ Physiol, February 1, 2003; 284(2): H654 - H667.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
O. Sorop, J. A. E. Spaan, and E. VanBavel
Pulsation-induced dilation of subendocardial and subepicardial arterioles: effect on vasodilator sensitivity
Am J Physiol Heart Circ Physiol, January 1, 2002; 282(1): H311 - H319.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
J. P. Versluis, J. W. Heslinga, P. Sipkema, and N. Westerhof
Microvascular pressure measurement reveals a coronary vascular waterfall in arterioles larger than 110 {micro}m
Am J Physiol Heart Circ Physiol, November 1, 2001; 281(5): H1913 - H1918.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
K. Morita, H. Mori, K. Tsujioka, A. Kimura, Y. Ogasawara, M. Goto, O. Hiramatsu, F. Kajiya, and E. O. Feigl
alpha -Adrenergic vasoconstriction reduces systolic retrograde coronary blood flow
Am J Physiol Heart Circ Physiol, December 1, 1997; 273(6): H2746 - H2755.
[Abstract] [Full Text] [PDF]

Home page
 J. Thorac. Cardiovasc. Surg.Home page
R. Cartier, O. S. Dias, M. Pellerin, Y. Hebert, and Y. Leclerc
CHANGING FLOW PATTERN OF THE INTERNAL THORACIC ARTERY UNDERGOING CORONARY BYPASS GRAFTING: CONTINUOUS-WAVE DOPPLER ASSESSMENT
J. Thorac. Cardiovasc. Surg., July 1, 1996; 112(1): 52 - 58.
[Abstract] [Full Text]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
S. Chabert and L. A. Taber
Intramyocardial pressure measurements in the stage 18 embryonic chick heart
Am J Physiol Heart Circ Physiol, April 1, 2002; 282(4): H1248 - H1254.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online