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Am J Physiol Heart Circ Physiol 250: H889-H891, 1986;
0363-6135/86 $5.00
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AJP - Heart and Circulatory Physiology, Vol 250, Issue 5 889-H891, Copyright © 1986 by American Physiological Society

ARTICLES

Denervation increases myogenic tone in a resistance artery in the growing rabbit ear

E. I. Mangiarua, E. H. Joyce and R. D. Bevan

The effect of chronic sympathetic and sensory denervation of the growing rabbit ear vasculature on myogenic tone in a resistance artery was studied. Unilateral superior cervical ganglionectomy and section of greater and anterior auricular nerves were performed at 4 wk of age. Compared with the contralateral control, 2 and 6 wk later, the denervated artery developed greater stretch-dependent myogenic tone. This phenomenon may partially account for the return of tone described in the denervated ear vasculature.




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