AJP - Heart Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 270: H1736-H1743, 1996;
0363-6135/96 $5.00
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Lanir, Y.
Right arrow Articles by Ben-Haim, S. A.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Lanir, Y.
Right arrow Articles by Ben-Haim, S. A.

AJP - Heart and Circulatory Physiology, Vol 270, Issue 5 1736-H1743, Copyright © 1996 by American Physiological Society

ARTICLES

Effect of myocardial swelling on residual strain in the left ventricle of the rat

Y. Lanir, G. Hayam, M. Abovsky, A. Y. Zlotnick, G. Uretzky, E. Nevo and S. A. Ben-Haim
Department of Biomedical Engineering Julius Silver Institute of Biomedical Sciences, Bruce Rappaport Faculty of Medicine, Haifa, Israel.

Left ventricular (LV) residual strain in the unloaded state was shown previously to affect LV performance. The interrelationship between myocardial swelling and LV residual strain was studied, both experimentally and theoretically. Myocardial swelling was induced by retrograde perfusion of beating, nonworking, isolated rat hearts with perfusate of graded osmolarities (200-420 mosM). The opening angle (an index of residual strain), in radially cut equatorial cross-sectional slices, and their water content were measured in 40 arrested rat LV. Both water content and opening angle decreased significantly with osmolarity from 84.2 +/- 0.45% and 77.2 +/- 9.2 degrees at 200 mosM to 76.5 +/- 1.05% and 36.3 +/- 9.8 degrees at 420 mosM (P < 0.001, respectively). A morphologically based theoretical model was developed and yielded as swelling residual strain relationship, which agrees well with the data. Our results indicate that myocardial swelling is strongly related to LV residual strain, suggesting that swelling, through its effect on residual strain, can affect both LV function and its adaptation to varying loading conditions.


This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
E. U. Azeloglu, M. B. Albro, V. A. Thimmappa, G. A. Ateshian, and K. D. Costa
Heterogeneous transmural proteoglycan distribution provides a mechanism for regulating residual stresses in the aorta
Am J Physiol Heart Circ Physiol, March 1, 2008; 294(3): H1197 - H1205.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
X. Guo, Y. Lanir, and G. S. Kassab
Effect of osmolarity on the zero-stress state and mechanical properties of aorta
Am J Physiol Heart Circ Physiol, October 1, 2007; 293(4): H2328 - H2334.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
D. Rehal, X. Guo, X. Lu, and G. S. Kassab
Duration of no-load state affects opening angle of porcine coronary arteries
Am J Physiol Heart Circ Physiol, May 1, 2006; 290(5): H1871 - H1878.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
F. S. A. Cavalcante, S. Ito, K. Brewer, H. Sakai, A. M. Alencar, M. P. Almeida, J. S. Andrade Jr., A. Majumdar, E. P. Ingenito, and B. Suki
Mechanical interactions between collagen and proteoglycans: implications for the stability of lung tissue
J Appl Physiol, February 1, 2005; 98(2): 672 - 679.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online