AJP - Heart Ad Instruments
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 273: H2436-H2441, 1997;
0363-6135/97 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ray, C. A.
Right arrow Articles by Mahoney, E. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ray, C. A.
Right arrow Articles by Mahoney, E. T.
Vol. 273, Issue 5, H2436-H2441, November 1997

Muscle cooling delays activation of the muscle metaboreflex in humans

Chester A. Ray, Keith M. Hume, Kathryn H. Gracey, and Edward T. Mahoney

Autonomic and Cardiovascular Control Laboratory, Department of Exercise Science, University of Georgia, Athens, Georgia 30602

Elevation of muscle temperature has been shown to increase muscle sympathetic nerve activity (MSNA) during isometric exercise in humans. The purpose of the present study was to evaluate the effect of muscle cooling on MSNA responses during exercise. Eight subjects performed ischemic isometric handgrip at 30% of maximal voluntary contraction to fatigue followed by 2 min of postexercise muscle ischemia (PEMI), with and without local cooling of the forearm. Local cooling of the forearm decreased forearm muscle temperature from 31.8 ± 0.4 to 23.1 ± 0.8°C (P = 0.001). Time to fatigue was not different during the control and cold trials (156 ± 11 and 154 ± 5 s, respectively). Arterial pressures and heart rate were not significantly affected by muscle cooling during exercise, although heart rate tended to be higher during the second minute of exercise (P = 0.053) during muscle cooling. Exercise-induced increases in MSNA were delayed during handgrip with local cooling compared with control. However, MSNA responses at fatigue and PEMI were not different between the two conditions. These findings suggest that muscle cooling delayed the activation of the muscle metaboreflex during ischemic isometric exercise but did not prevent its full expression during fatiguing contraction. These results support the concept that muscle temperature can play a role in the regulation of MSNA during exercise.

sympathetic nerve activity; group III and IV afferents; exercise pressor reflex; isometric contraction; muscle ischemia; muscle temperature


This article has been cited by other articles:


Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
J. S. Cook and C. A. Ray
Modulation of muscle sympathetic nerve activity to muscle heating during dynamic exercise
Am J Physiol Regulatory Integrative Comp Physiol, May 1, 2009; 296(5): R1439 - R1444.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
N. T. Kuipers, C. L. Sauder, M. L. Kearney, and C. A. Ray
Changes in forearm muscle temperature alter renal vascular responses to isometric handgrip
Am J Physiol Heart Circ Physiol, December 1, 2007; 293(6): H3432 - H3439.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. D. Delp and D. S. O'Leary
Integrative control of the skeletal muscle microcirculation in the maintenance of arterial pressure during exercise
J Appl Physiol, September 1, 2004; 97(3): 1112 - 1118.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
M. Shibasaki, M. Sakai, M. Oda, and C. G. Crandall
Muscle mechanoreceptor modulation of sweat rate during recovery from moderate exercise
J Appl Physiol, June 1, 2004; 96(6): 2115 - 2119.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
K. J. Doerzbacher and C. A. Ray
Muscle sympathetic nerve responses to physiological changes in prostaglandin production in humans
J Appl Physiol, February 1, 2001; 90(2): 624 - 629.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online