AJP - Heart Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 273: H2627-H2631, 1997;
0363-6135/97 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Véras-Silva, A. S.
Right arrow Articles by Krieger, E. M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Véras-Silva, A. S.
Right arrow Articles by Krieger, E. M.
Vol. 273, Issue 6, H2627-H2631, December 1997

Low-intensity exercise training decreases cardiac output and hypertension in spontaneously hypertensive rats

Acácio Salvador Véras-Silva, Katt Coelho Mattos, Nilo Sérgio Gava, Patricia Chakur Brum, Carlos Eduardo Negrão, and Eduardo Moacyr Krieger

Hypertension Unit, Heart Institute, Faculty of Medicine, and Exercise Physiology Laboratory, Physical Education and Sports School, University of São Paulo, São Paulo, Brazil 05403-000

The decrease in cardiac sympathetic tone and heart rate after low-intensity exercise training may have hemodynamic consequences in spontaneously hypertensive rats (SHR). The effects of exercise training of low and high intensity on resting blood pressure, cardiac output, and total peripheral resistance were studied in sedentary (n = 17), low- (n = 17), and high-intensity exercise-trained (n = 17) SHR. Exercise training was performed on a treadmill for 60 min, 5 times per week for 18 weeks, at 55% or 85% maximum oxygen uptake. Blood pressure was evaluated by a cannula inserted into the carotid artery, and cardiac output was evaluated by a microprobe placed around the ascending aorta. Low-intensity exercise-trained rats had a significantly lower mean blood pressure than sedentary and high-intensity exercise-trained rats (160 ± 4 vs. 175 ± 3 and 173 ± 2 mmHg, respectively). Cardiac index (20 ± 1 vs. 24 ± 1 and 24 ± 1 ml · min-1 · 100 g-1, respectively) and heart rate (332 ± 6 vs. 372 ± 14 and 345 ± 9 beats/min, respectively) were significantly lower in low-intensity exercise-trained rats than in sedentary and high-intensity exercise-trained rats. No significant difference was observed in stroke volume index and total peripheral resistance index in all groups studied. In conclusion, low-intensity, but not high-intensity, exercise training decreases heart rate and cardiac output and, consequently, attenuates hypertension in SHR.

blood pressure; exercise training intensity; hemodynamics


This article has been cited by other articles:


Home page
 Exp PhysiolHome page
A. G. Filho, A. J. Ferreira, S. H. S. Santos, S. R. S. Neves, E. R. Silva Camargos, L. K. Becker, H. A. Belchior, M. F. Dias-Peixoto, S. V. B. Pinheiro, and R. A. S. Santos
Selective increase of angiotensin(1-7) and its receptor in hearts of spontaneously hypertensive rats subjected to physical training
Exp Physiol, May 1, 2008; 93(5): 589 - 598.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
H. L. Collins, A. M. Loka, and S. E. DiCarlo
Daily exercise-induced cardioprotection is associated with changes in calcium regulatory proteins in hypertensive rats
Am J Physiol Heart Circ Physiol, February 1, 2005; 288(2): H532 - H540.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Regul. Integr. Comp. Physiol.Home page
J. M. Kramer, J. A. Beatty, H. R. Little, E. D. Plowey, and T. G. Waldrop
Chronic exercise alters caudal hypothalamic regulation of the cardiovascular system in hypertensive rats
Am J Physiol Regulatory Integrative Comp Physiol, February 1, 2001; 280(2): R389 - R397.
[Abstract] [Full Text] [PDF]

Home page
 J. Pharmacol. Exp. Ther.Home page
L. Brynne, L. K. Paalzow, and M. O. Karlsson
Consequence of Exercise on the Cardiovascular Effects of l-Propranolol in Spontaneously Hypertensive Rats
J. Pharmacol. Exp. Ther., September 1, 2000; 294(3): 1201 - 1208.
[Abstract] [Full Text]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online