AJP - Heart Calcium Transients and Cell-Sarcomere
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 279: H2464-H2476, 2000;
0363-6135/00 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via ISI Web of Science (21)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Mor-Avi, V.
Right arrow Articles by Lang, R.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Mor-Avi, V.
Right arrow Articles by Lang, R.
Vol. 279, Issue 5, H2464-H2476, November 2000

Normal values of regional left ventricular endocardial motion: multicenter color kinesis study

Victor Mor-Avi1, Kirk Spencer1, John Gorcsan2, Anthony Demaria3, Thomas Kimball4, Mark Monaghan5, Julio Perez6, Jing Ping Sun7, Lynn Weinert1, James Bednarz1, Keith Collins1, Kathy Edelman2, Oi Ling Kwan3, Betty Glascock4, Jane Hancock5, Chris Baumann6, James Thomas7, and Roberto Lang1

1 The University of Chicago, Chicago, Illinois 60637; 2 University of Pittsburgh, Pittsburgh, Pennsylvania 15261; 3 University of California, San Diego, California 92103; 4 Children's Hospital, Cincinnati 45229, 7 Cleveland Clinic Foundation, Cleveland, Ohio 44195; 5 King's College, London, United Kingdom WC2R 2LS; and 6 Washington University, St. Louis, Missouri 63110

Our goal was to establish normal values for quantitative color kinesis indexes of left ventricular (LV) wall motion over a wide range of ages, which are required for objective diagnosis of regional systolic and diastolic dysfunction. Color-encoded images were obtained in 194 normal subjects (95 males, 99 females, age 2 mo to 79 yr) in four standard views. Quantitative indexes of magnitude and timing of systolic and diastolic function were studied for age- and gender-related differences. Normal limits of all ejection and filling indexes were in a narrow range (<= 25% of the mean), with no major gender-related differences. Despite invariable ejection fractions, both peak filling and ejection rates decreased with age (30 and 20%, correspondingly) with a concomitant increase in mean filling and ejection times, resulting in five- and twofold increases in the late to early filling and ejection ratios, correspondingly. Diastolic asynchrony increased with age (from 4.7 ± 2.0 to 6.4 ± 3.2 from the 2nd to 7th decade). The normal values of color kinesis indexes should allow objective detection of regional LV systolic and diastolic dysfunction.

echocardiography; ultrasound imaging; ventricular function; wall motion


This article has been cited by other articles:


Home page
 HeartHome page
H. Jaochim Nesser, L. Sugeng, C. Corsi, L. Weinert, J. Niel, C. Ebner, R. Steringer-Mascherbauer, F. Schmidt, G. Schummers, R. M Lang, et al.
Volumetric analysis of regional left ventricular function with real-time three-dimensional echocardiography: validation by magnetic resonance and clinical utility testing
Heart, May 1, 2007; 93(5): 572 - 578.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
M. Slama, J. Ahn, M. Peltier, J. Maizel, D. Chemla, J. Varagic, D. Susic, C. Tribouilloy, and E. D. Frohlich
Validation of echocardiographic and Doppler indexes of left ventricular relaxation in adult hypertensive and normotensive rats
Am J Physiol Heart Circ Physiol, September 1, 2005; 289(3): H1131 - H1136.
[Abstract] [Full Text] [PDF]

Home page
 Exp PhysiolHome page
Q. Ruan and S. F Nagueh
Effect of age on left ventricular systolic function in humans: a study of systolic isovolumic acceleration rate
Exp Physiol, July 1, 2005; 90(4): 527 - 534.
[Abstract] [Full Text] [PDF]

Home page
 Anesth. Analg.Home page
M. V. Podgoreanu, G. N. Djaiani, E. Davis, B. Phillips-Bute, and J. P. Mathew
Quantitative Echocardiographic Assessment of Regional Wall Motion and Left Ventricular Asynchrony with Color Kinesis in Cardiac Surgery Patients
Anesth. Analg., May 1, 2003; 96(5): 1294 - 1300.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online