AJP - Heart Calcium Transients and Cell-Sarcomere
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 282: H850-H854, 2002; doi:10.1152/ajpheart.00746.2001
0363-6135/02 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (21)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Faber, J. J.
Right arrow Articles by Anderson, D. F.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Faber, J. J.
Right arrow Articles by Anderson, D. F.
Vol. 282, Issue 3, H850-H854, March 2002

Absorption of amniotic fluid by amniochorion in sheep

J. Job Faber and Debra F. Anderson

Department Physiology and Pharmacology, School of Medicine, Oregon Health Sciences University, Portland, Oregon 97201

Swallowing of amniotic fluid and lung fluid inflow were eliminated in 10 chronically instrumented fetuses. The urachus was ligated, and fetal was urine drained to the outside. At the beginning and the end of 21 experiments of 66 ± 5 (SE) h duration, all amniotic fluid was temporarily drained to the outside for volume measurement and sampling. Amniotic fluid osmolalities and oncotic pressures were experimentally controlled. Amniochorionic absorption of amniotic fluid depended strongly on the osmolality difference between amniotic fluid and fetal plasma (P < 0.001), but at zero osmolality difference there still was a mean absorption rate of 23.8 ± 4.7 (SE) ml/h (P < 0.001). Absorption was unaffected by the protein concentration difference between amniotic fluid and fetal plasma, but infused bovine albumin in the amniotic fluid was absorbed at a rate of 1.8 ± 0.4 g/h (P < 0.001), corresponding to a volume flow of fluid of 33.8 ± 6.1 ml/h (P < 0.001). Fluid absorption in the amniochorion is driven in part by crystalloid osmotic pressure, but about 25 ml/h is absorbed by a path that is permeable to protein. That path has the physiological characteristics of lymphatic drainage, although no anatomic basis is known to exist for a lymphatic system in the amniochorion.

oncotic pressure; volume homeostasis; lymphatics


This article has been cited by other articles:


Home page
 Reproductive SciencesHome page
P. Robertson, J. J. Faber, R. A. Brace, S. Louey, A. R. Hohimer, L. E. Davis, and D. F. Anderson
Responses of Amniotic Fluid Volume and Its Four Major Flows to Lung Liquid Diversion and Amniotic Infusion in the Ovine Fetus
Reproductive Sciences, January 1, 2009; 16(1): 88 - 93.
[Abstract] [PDF]

Home page
 Reproductive SciencesHome page
C. Y. Cheung and R. A. Brace
Unidirectional Transport Across Cultured Ovine Amniotic Epithelial Cell Monolayer
Reproductive Sciences, December 1, 2008; 15(10): 1054 - 1058.
[Abstract] [PDF]

Home page
 NeoReviewsHome page
W. M. Gilbert
Amniotic Fluid Dynamics
NeoReviews, June 1, 2006; 7(6): e292 - e299.
[Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
J. Faber, D. Anderson, R. Hohimer, Q. Yang, G. Giraud, and L. Davis
Function curve of the membranes that regulate amniotic fluid volume in sheep
Am J Physiol Heart Circ Physiol, July 1, 2005; 289(1): H146 - H150.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Renal Physiol.Home page
D. Anderson, Q. Yang, A. Hohimer, J. Faber, G. Giraud, and L. Davis
Intramembranous absorption rate is unaffected by changes in amniotic fluid composition
Am J Physiol Renal Physiol, May 1, 2005; 288(5): F964 - F968.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
Q. Yang, L. Davis, A. Hohimer, J. Faber, and D. Anderson
Regulatory response to washout of amniotic fluid in sheep
Am J Physiol Heart Circ Physiol, March 1, 2005; 288(3): H1339 - H1343.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online