AJP - Heart Ad Instruments
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 282: H1189-H1196, 2002; doi:10.1152/ajpheart.00227.2001
0363-6135/02 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (8)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Arnar, D. O.
Right arrow Articles by Martins, J. B.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Arnar, D. O.
Right arrow Articles by Martins, J. B.
Vol. 282, Issue 4, H1189-H1196, April 2002

Purkinje involvement in arrhythmias after coronary artery reperfusion

David O. Arnar and James B. Martins

Division of Cardiovascular Diseases, Department of Internal Medicine, University of Iowa College of Medicine, Iowa City; and Veterans Administration Medical Center, Iowa City, Iowa 52242

Previous studies have indicated that the endocardium may be responsible for a large portion of ventricular tachycardia (VT) seen with reperfusion of ischemic myocardium. To evaluate the role of the Purkinje system in nonreentrant VT arising from the endocardium after reperfusion, the anterior descending coronary artery was occluded for 20 min and then reperfused in 23 dogs after instrumentation of the risk zone with 21 multipolar plunge needles. VT with focal Purkinje origin was defined as a focal endocardial VT with Purkinje potentials recorded before the earliest endocardial myopotential. A total of 19 VTs (mean cycle length 214 ± 2 ms) were observed with 11 (58%) having focal Purkinje origin. Fifty-eight percent of the VTs degenerated to ventricular fibrillation, with occurrences of two or more independent foci per complex (seen in 7 of 11 compared with 1 of 8 nonsustained VTs). In conclusion, these data show that Purkinje tissue may be important in the genesis of reperfusion VT.

mapping; ventricles


This article has been cited by other articles:


Home page
 Phil Trans R Soc AHome page
P. Stewart, O. V. Aslanidi, D. Noble, P. J. Noble, M. R. Boyett, and H. Zhang
Mathematical models of the electrical action potential of Purkinje fibre cells
Phil Trans R Soc A, June 13, 2009; 367(1896): 2225 - 2255.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
D. J. Dosdall, P. B. Tabereaux, J. J. Kim, G. P. Walcott, J. M. Rogers, C. R. Killingsworth, J. Huang, P. G. Robertson, W. M. Smith, and R. E. Ideker
Chemical ablation of the Purkinje system causes early termination and activation rate slowing of long-duration ventricular fibrillation in dogs
Am J Physiol Heart Circ Physiol, August 1, 2008; 295(2): H883 - H889.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
D. O. Arnar, D. Xing, and J. B. Martins
Overdrive pacing of early ischemic ventricular tachycardia: evidence for both reentry and triggered activity
Am J Physiol Heart Circ Physiol, March 1, 2005; 288(3): H1124 - H1130.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online