AJP - Heart AJP: Gastrointestinal and Liver Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 283: H2650-H2659, 2002; doi:10.1152/ajpheart.00111.2002
0363-6135/02 $5.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (32)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Dokos, S.
Right arrow Articles by LeGrice, I. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Dokos, S.
Right arrow Articles by LeGrice, I. J.
Vol. 283, Issue 6, H2650-H2659, December 2002

Shear properties of passive ventricular myocardium

Socrates Dokos, Bruce H. Smaill, Alistair A. Young, and Ian J. LeGrice

Department of Physiology, School of Medicine, University of Auckland, Auckland, New Zealand

We examined the shear properties of passive ventricular myocardium in six pig hearts. Samples (3 × 3 × 3 mm) were cut from adjacent regions of the lateral left ventricular midwall, with sides aligned with the principal material axes. Four cycles of sinusoidal simple shear (maximum shear displacements of 0.1-0.5) were applied separately to each specimen in two orthogonal directions. Resulting forces along the three axes were measured. Three specimens from each heart were tested in different orientations to cover all six modes of simple shear deformation. Passive myocardium has nonlinear viscoelastic shear properties with reproducible, directionally dependent softening as strain is increased. Shear properties were clearly anisotropic with respect to the three principal material directions: passive ventricular myocardium is least resistant to simple shear displacements imposed in the plane of the myocardial layers and most resistant to shear deformations that produce extension of the myocyte axis. Comparison of results for the six different shear modes suggests that simple shear deformation is resisted by elastic elements aligned with the microstructural axes of the tissue.

mechanical and constitutive properties; anisotropy; strain softening and history; shear testing; laminar structure


This article has been cited by other articles:


Home page
 Exp PhysiolHome page
A. A. Young and A. F. Frangi
Computational cardiac atlases: from patient to population and back
Exp Physiol, May 1, 2009; 94(5): 578 - 596.
[Abstract] [Full Text] [PDF]

Home page
 Eur J EchocardiogrHome page
B. H. Bijnens, M. Cikes, P. Claus, and G. R. Sutherland
Velocity and deformation imaging for the assessment of myocardial dysfunction
Eur J Echocardiogr, March 1, 2009; 10(2): 216 - 226.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. J. Pope, G. B. Sands, B. H. Smaill, and I. J. LeGrice
Three-dimensional transmural organization of perimysial collagen in the heart
Am J Physiol Heart Circ Physiol, September 1, 2008; 295(3): H1243 - H1252.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
Y. Liu, W. Zhang, and G. S. Kassab
Effects of myocardial constraint on the passive mechanical behaviors of the coronary vessel wall
Am J Physiol Heart Circ Physiol, January 1, 2008; 294(1): H514 - H523.
[Abstract] [Full Text] [PDF]

Home page
 Eur. J. Cardiothorac. Surg.Home page
S. H. Gilbert, A. P. Benson, P. Li, and A. V. Holden
Regional localisation of left ventricular sheet structure: integration with current models of cardiac fibre, sheet and band structure
Eur. J. Cardiothorac. Surg., August 1, 2007; 32(2): 231 - 249.
[Abstract] [Full Text] [PDF]

Home page
 Circ. Res.Home page
S. Nishimura, S. Nagai, M. Katoh, H. Yamashita, Y. Saeki, J.-i. Okada, T. Hisada, R. Nagai, and S. Sugiura
Microtubules Modulate the Stiffness of Cardiomyocytes Against Shear Stress
Circ. Res., January 6, 2006; 98(1): 81 - 87.
[Abstract] [Full Text] [PDF]

Home page
 PhysiologyHome page
P. Hunter and P. Nielsen
A Strategy for Integrative Computational Physiology
Physiology, October 1, 2005; 20(5): 316 - 325.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
L. Brown
Cardiac extracellular matrix: a dynamic entity
Am J Physiol Heart Circ Physiol, September 1, 2005; 289(3): H973 - H974.
[Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
R. S. Kirton, A. J. Taberner, P. M. F. Nielsen, A. A. Young, and D. S. Loiselle
Effects of BDM, [Ca2+]o, and temperature on the dynamic stiffness of quiescent cardiac trabeculae from rat
Am J Physiol Heart Circ Physiol, April 1, 2005; 288(4): H1662 - H1667.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. B. C. Dang, J. M. Guccione, J. M. Mishell, P. Zhang, A. W. Wallace, R. C. Gorman, J. H. Gorman III, and M. B. Ratcliffe
Akinetic myocardial infarcts must contain contracting myocytes: finite-element model study
Am J Physiol Heart Circ Physiol, April 1, 2005; 288(4): H1844 - H1850.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
R. S. Kirton, A. J. Taberner, A. A. Young, P. M. F. Nielsen, and D. S. Loiselle
Strain softening is not present during axial extensions of rat intact right ventricular trabeculae in the presence or absence of 2,3-butanedione monoxime
Am J Physiol Heart Circ Physiol, February 1, 2004; 286(2): H708 - H715.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online