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Am J Physiol Heart Circ Physiol 287: H1891-H1894, 2004; doi:10.1152/classicessays.00003.2004
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EDITORIAL FOCUS

ESSAYS ON APS CLASSIC PAPERS

Berne's adenosine hypothesis of coronary blood flow control

Department of Physiology and Biophysics, University of Washington, Seattle, Washington 98195

ABSTRACT

This essay looks at the historical significance of an APS classic paper that is freely available online:

Berne RM. Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. Am J Physiol 204: 317–322, 1963 (http://ajplegacy.physiology.org/cgi/reprint/204/2/317).

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