AJP - Heart Watch the video to see how APS reaches out to developing nations.
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol 291: H1761-H1767, 2006. First published May 26, 2006; doi:10.1152/ajpheart.00280.2006
0363-6135/06 $8.00
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Supplmental Videos
Right arrow All Versions of this Article:
291/4/H1761    most recent
00280.2006v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Sakurai, T.
Right arrow Articles by Terui, N.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Sakurai, T.
Right arrow Articles by Terui, N.

Effects of sympathetically induced vasomotion on tissue-capillary fluid exchange

Terumi Sakurai and Naohito Terui

Department of Physiology, Institute of Basic Medical Sciences, Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Japan

Submitted 17 March 2006 ; accepted in final form 7 May 2006

The spontaneous and rhythmic constriction of peripheral arterioles, which is not associated with the cardiac or respiratory cycles, is called vasomotion. Vasomotion is observed in various tissues of various species, but the physiological role of vasomotion has not been clarified because of the difficulty in controlling the appearance of vasomotion in in vivo preparations. We developed a method of controlling vasomotion in in vivo experiments. The electrical stimulation of the cervical sympathetic nerve could reproducibly evoke vasomotion in rabbit ear skin. The frequencies of the evoked vasomotion were 0.04–0.07 Hz, which corresponded to spontaneously occurring vasomotion that has been reported before. Vasomotion was always evoked between 25 and 35°C. At lower than 17°C or higher than 37°C, vasomotion was not evoked. With the use of this method of evoking vasomotion in vivo, the role of vasomotion in tissue perfusion was examined. A tracer (Cr-EDTA) was injected into the ear tissue, and tracer fading was then measured by using a camera. The rates of fading (clearance) of the tracer with vasomotion were significantly greater (1.7 to 8.1 times) than those without vasomotion. These results provided evidence that vasomotion enhanced tissue perfusion.

flow motion; microcirculation


Address for reprint requests and other correspondence: N. Terui, Dept. of Physiology, Institute of Basic Medical Sciences, Graduate School of Comprehensive Human Sciences, Univ. of Tsukuba,. 1–1-1 Tennodai, Tsukuba-shi, Ibaraki-ken 305–8575, Japan (e-mail: terui{at}md.tsukuba.ac.jp)






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Visit Other APS Journals Online
Copyright © 2006 by the American Physiological Society.