AJP - Heart Calcium Transients and Cell-Sarcomere
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Am J Physiol Heart Circ Physiol 295: H915-H916, 2008; doi:10.1152/classicessays.zh4-8503.2008 Free Article
0363-6135/08 $8.00
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EDITORIAL FOCUS

ESSAYS ON APS CLASSIC PAPERS

The beginning of a fantastic, unanswered question: is 5-HT involved in systemic hypertension?

Stephanie W. Watts

Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan

ABSTRACT

This essay examines the historical significance of an APS classic paper that is freely available online:

McGregor DD, Smirk FH. Vascular responses to 5-hydroxytryptamine in genetic and renal hypertensive rats. Am J Physiol 219: 687–690, 1970. (http://ajplegacy.physiology.org/cgi/reprint/219/3/687)


Address for reprint requests and other correspondence: S. W. Watts, Dept. of Pharmacology and Toxicology, B445 Life Sciences Bldg., Michigan State Univ., East Lansing, MI 48824-1317 (e-mail: wattss{at}msu.edu)






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