Supplemental Video

One video file in Quicktime format.

Files in this Data Supplement:

• Video - The time-lapse movie shows a freshly isolated pericyte-containing retinal microvessel before, during, and after exposure to extracellular lactate. Differential interference contrast images were captured at 8-s intervals for a period of 30 min. This movie speeds up events by ~225-fold. Vasoconstriction occurred soon after the onset of exposure to lactate. The frames labeled "lactate" indicate when this pericyte-containing microvessel was exposed to 20 mM lactate. Arrows point to the region of maximal vasoconstriction.