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Transmural reentry during acute global ischemia and reperfusion in canine ventricular muscle

Jiashin Wu and Douglas P. Zipes

Krannert Institute of Cardiology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202

Notes: Movies are shown in rectangular frames, which include areas outside of tissue. The higher noises in the areas outside of tissue are from the signal normalization (to the respective peak-to-peak amplitude of signal from each sensor).  Each movie contains 1.2 seconds of data.

Ischemia (Arterial occlusion):

    Tissue 1:

        Movie 1 (Before ischemia, Fig. 2, E).

        Movie 2 (298 seconds of ischemia, slowed transmural propagation, Fig. 2 B and F).

        Movie 3 (520 seconds of ischemia, reentry, Fig. 2 C and G).

    Tissue 2:

        Movie 4 (672 seconds of ischemia, reentry, Fig. 3).

Reperfusion at 1/2 of pre-ischemia flow rate after 25 minutes of ischemia:

        Movie 5 (25 seconds of reperfusion, epi-mid-myocardial recovery, Fig. 4, B).

        Movie 6 (36 seconds of reperfusion, further epi-mid-myocardial recovery, Fig. 4, C).

        Movie 7 (87 seconds of reperfusion, fibrillation, Fig. 4, D).

        Movie 8 (176 seconds of reperfusion, organized clockwise reentry, Fig. 4, I).

        Movie 9 (263 seconds of reperfusion, organized counter clockwise reentry, Fig. 4, E and J).

        Movie 10 (376 seconds of reperfusion, endocardial-to-epicardial propagation, Fig. 4, F and K).

This Article Abstract Full Text Services Email this article to a friend Alert me to new issues of the journal