HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Search for Related Content

CORRIGENDUM

Corrigendum

Volume 61, March 2007

Adebiyi A, Zhao G, Cheranov SY, Ahmed A, Jaggar JH. Caveolin-1 abolishment attenuates the myogenic response in murine cerebral arteries. Am J Physiol Heart Circ Physiol 292: H1584-H1592. First published November 10, 2006; doi:10.1152/ajpheart.00584.2006; http://ajpheart.physiology.org/cgi/content/full/292/3/H1584.

On page H1588, the sentence in the third line of the left column should read as "Total K_Ca channel protein, when normalized to actin, was similar in cav-1^+/+ and cav-1^–/– arteries (Fig. 6, C and D; P > 0.05)." (Corrected text presented in boldface.)

View larger version (24K): [in this window] [in a new window]   Fig. 6. Iberiotoxin induces a similar depolarization and constriction in cav-1+/+ and cav-1–/– arteries, but total arterial KCa channel protein is similar. A: membrane depolarization induced by iberiotoxin (100 nM) is similar in pressurized (50 mmHg) cav-1+/+ (n = 6) and cav-1–/– (n = 6) arteries. B: iberiotoxin (100 nM) induces a similar constriction in cav-1+/+ (n = 6) and cav-1–/– (n = 6) arteries pressurized to 50 mmHg. C: representative Western immunoblots for KCa channel -subunit and actin protein in cav-1+/+ and cav-1–/– cerebral artery lysates. D: mean data illustrating digital densitometric analysis of bands obtained by Western immunoblotting for KCa channel -subunit normalized to actin (n = 4 separate experiments, with each experiment performed using arteries pooled from 4 mice, giving a total of 16 cav-1+/+ and 16 cav-1–/– mice used to obtain data).

View larger version (30K): [in this window] [in a new window]   Fig. 1. Myogenic constriction is attenuated in caveolin-1 (cav-1)–/– arteries. A: Western immunoblot illustrates the presence of cav-1 in cerebral arteries of control mice and the absence of cav-1 in cerebral arteries of cav-1–/– mice (data are representative of 4 experiments). In contrast, actin was detected in both cav-1+/+ and cav-1–/– arteries. B: representative traces illustrate that an elevation in intravascular pressure from 10 to 50 mmHg induces an attenuated myogenic constriction in a cav-1–/– artery, when compared with the response in a cav-1+/+ artery. C: relationship between intravascular pressure and myogenic tone in cav-1+/+ (n = 6) and cav-1–/– (n = 6) arteries. *P < 0.05 when compared with cav-1+/+ arteries at the same pressure. B and D: diltiazem (DTZ) significantly increased the diameter of both cav-1+/+ (n = 6) and cav-1–/– (n = 6) arteries. In the continued presence of DTZ, removal of extracellular Ca2+ did not cause any further increase in diameter. #P < 0.05 when compared with the respective control; P < 0.05 when compared with cav-1+/+ at the same pressure. NS, nonsignificant difference.

This article has been cited by other articles:

				S. Albinsson, Y. Shakirova, A. Rippe, M. Baumgarten, B.-I. Rosengren, C. Rippe, R. Hallmann, P. Hellstrand, B. Rippe, and K. Sward Arterial remodeling and plasma volume expansion in caveolin-1-deficient mice Am J Physiol Regulatory Integrative Comp Physiol, September 1, 2007; 293(3): R1222 - R1231. [Abstract] [Full Text] [PDF]

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Search for Related Content