AJP - Heart Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol (June 21, 2002). doi:10.1152/ajpheart.00169.2002
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
283/4/H1695    most recent
00169.2002v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (6)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Kuo, T. B. J.
Right arrow Articles by Yang, C. C.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Kuo, T. B. J.
Right arrow Articles by Yang, C. C.

Articles in PresS, published online ahead of print June 21, 2002
Am J Physiol Heart Circ Physiol, 10.1152/ajpheart.00169.2002
Submitted on February 27, 2002
Accepted on June 20, 2002

Sexual dimorphism in complexity of cardiac pacemaker activity

Terry B. J. Kuo1* and Cheryl C. Yang2

1 Tzu Chi University, Institute of Neuroscience, Hualien, Taiwan; Tzu Chi Buddhist General Hospital, Department of Neurology, Hualien, Taiwan
2 Tzu Chi University, Department of Physiology, Hualien, Taiwan

* To whom correspondence should be addressed. E-mail: tbjkuo{at}ms33.hinet.net.

This study explored the effects of gender and aging on complexity of cardiac pacemaker activity. Electrocardiogram signals were studied in normal women (n = 240) and men (n = 240) ranging in age from 40 to 79 yr. Nonlinear analysis of short-term resting R-R intervals was performed using the correlation dimension (CD), approximate entropy (ApEn), and largest Lyapunov exponent (LLE). Evidence of nonlinear structure was obtained by the surrogate data test. CD, ApEn, and LLE were negatively correlated with age. Despite similar means and standard deviations of the R-R intervals, women had a significantly higher CD, ApEn, and LLE compared with men in the age strata 40-44 and 45-49 yr. CD and ApEn were strongly (r > 0.71) correlated with low- and high-frequency components. We conclude that the resting cardiac pacemaker activity of women is more complex than that of men in middle age, and the gender-related difference diminishes after the age of 50 yr. The higher complexity implies a more comprehensive neural modulation.




This article has been cited by other articles:


Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
X. Bai, J. Li, L. Zhou, and X. Li
Influence of the menstrual cycle on nonlinear properties of heart rate variability in young women
Am J Physiol Heart Circ Physiol, August 1, 2009; 297(2): H765 - H774.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. L. Chen, H. H. Lin, W. C. Orr, C. C. H. Yang, and T. B. J. Kuo
Transfer function analysis of heart rate variability in response to water intake: correlation with gastric myoelectrical activity
J Appl Physiol, June 1, 2004; 96(6): 2226 - 2230.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
C. C. Liu, T. B. J. Kuo, and C. C. H. Yang
Effects of estrogen on gender-related autonomic differences in humans
Am J Physiol Heart Circ Physiol, November 1, 2003; 285(5): H2188 - H2193.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 1976 by the American Physiological Society.