| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
|
|
|
|||||||
|
|||||||||
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
1 Erasmus University Medical Center
* To whom correspondence should be addressed. E-mail: b.m.vandalen{at}erasmusmc.nl.
The increasing number and proportion of aged individuals in the population warrants knowledge of normal physiologic changes of left ventricular (LV) biomechanics with advancing age. LV twist describes the instantaneous circumferential motion of the apex with respect to the base of the heart and has an important role in LV ejection and filling. This study sought to investigate the biomechanics behind age-related changes in LV twist by determining a broad spectrum of LV rotation parameters in different age groups, using speckle tracking echocardiography (STE). The final study population consisted of 61 healthy volunteers (age 16-74 year, 31 men). LV peak systolic rotation during the isovolumic contraction phase (Rotearly), LV peak systolic rotation during ejection (Rotmax), instantaneous LV peak systolic twist (Twistmax), the time to Rotearly, Rotmax, and Twistmax, and rotational deformation delay (defined as the difference of time to basal Rotmax and apical Rotmax) were determined by STE using QLAB Advanced Quantification Software (version 6.0, Philips, Best, The Netherlands). With increasing age, apical Rotmax (P <0.05), time to apical Rotmax (P <0.01), and Twistmax (P <0.01) increased, whereas basal Rotearly (P <0.001), time to basal Rotearly (P <0.001), and rotational deformation delay (P <0.05) decreased. Rotational deformation delay was significantly correlated to Twistmax (R2 = 0.20, P <0.05). In conclusion, Twistmax increased with ageing, resulting from both increased apical Rotmax and decreased rotational deformation delay between the apex and the base of the LV. This may explain the preservation of LV ejection fraction in the elderly.
This article has been cited by other articles:
|
|
 |
|
  T. T. Phan, G. N. Shivu, K. Abozguia, M. Gnanadevan, I. Ahmed, and M. Frenneaux Left ventricular torsion and strain patterns in heart failure with normal ejection fraction are similar to age-related changes Eur J Echocardiogr, August 1, 2009; 10(6): 793 - 800. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H.-J. Nesser, V. Mor-Avi, W. Gorissen, L. Weinert, R. Steringer-Mascherbauer, J. Niel, L. Sugeng, and R. M. Lang Quantification of left ventricular volumes using three-dimensional echocardiographic speckle tracking: comparison with MRI Eur. Heart J., July 1, 2009; 30(13): 1565 - 1573. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. M. van Dalen, O. I.I. Soliman, W. B. Vletter, F. Kauer, H. B. van der Zwaan, F. J. ten Cate, and M. L. Geleijnse Feasibility and reproducibility of left ventricular rotation parameters measured by speckle tracking echocardiography Eur J Echocardiogr, July 1, 2009; 10(5): 669 - 676. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B M van Dalen, F Kauer, O I I Soliman, W B Vletter, M Michels, F J t. Cate, and M L Geleijnse Influence of the pattern of hypertrophy on left ventricular twist in hypertrophic cardiomyopathy Heart, April 1, 2009; 95(8): 657 - 661. [Abstract] [Full Text] [PDF]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH |
| Visit Other APS Journals Online |
