AJP - Heart AJP: Regulatory, Integrative and Comparative Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol (September 12, 2002). doi:10.1152/ajpheart.00577.2002
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
284/1/H56    most recent
00577.2002v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Web of Science (10)
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Pasipoularides, A.
Right arrow Articles by Glower, D. D
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Pasipoularides, A.
Right arrow Articles by Glower, D. D

Articles in PresS, published online ahead of print September 12, 2002
Am J Physiol Heart Circ Physiol, 10.1152/ajpheart.00577.2002
Submitted on July 11, 2002
Accepted on August 30, 2002

RV functional imaging: 3D Echo-derived dynamic geometry and flow field simulations

Ares Pasipoularides1, Ming Shu2, Michael S Womack3, Ashish Shah3, Olaf von Ramm2, and Donald D Glower3*

1 Department of Surgery, Division of Cardiac and Thoracic Surgery, Duke University Medical Center, Durham, NC, USA; Center for Emerging Cardiovascular Technologies, Duke University Medical Center, Durham, NC, USA
2 Center for Emerging Cardiovascular Technologies, Duke University Medical Center, Durham, NC, USA
3 Department of Surgery, Division of Cardiac and Thoracic Surgery, Duke University Medical Center, Durham, NC, USA

* To whom correspondence should be addressed. E-mail: glowe001{at}mc.duke.edu.

We describe a novel functional imaging approach for quantitative analysis of RV blood flow patterns in specific experimental animals (or humans) using real-time 3-D echocardiography (RT3D). The method is independent of digital imaging modality used. It comprises three parts: First, a semi-automated segmentation aided by intraluminal contrast medium locates the RV endocardial surface. Then, a geometric scheme for dynamic RV chamber reconstruction applies a time interpolation procedure to the RT3D data to quantify wall geometry and motion at 400 Hz. A volumetric prism method validated the dynamic geometric reconstruction against simultaneous sonomicrometric canine measurements. Finally, the RV endocardial border motion information is used for mesh generation on a computational fluid dynamics solver to simulate development of the early RV diastolic inflow field. Boundary conditions (tessellated endocardial surface nodal velocities) for the solver are directly derived from the endocardial geometry and motion information. The new functional imaging approach may yield important kinematic information on the distribution of instantaneous velocities in the RV diastolic flow field of specific normal or diseased hearts.




This article has been cited by other articles:


Home page
 J. Appl. Physiol.Home page
E. L. Ritman, A. Pasipoularides, T. Arts, T. Delhaas, P. P. Sengupta, B. K. Khandheria, A. J. Tajik, A. Boussuges, and J. Regnard
To the editor: functional imaging(FI) combines imaging datasets and computational fluid dynamics to simulate cardiac flows.
J Appl Physiol, September 1, 2008; 105(3): 1015 - 1015.
[Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
C. Marabotti, R. Bedini, and A. L'Abbate
Right ventricular volume determination: not a matter for echocardiography
J Appl Physiol, May 1, 2008; 104(5): 1547 - 1547.
[Full Text] [PDF]

Home page
 CirculationHome page
C. Cortina, J. Bermejo, R. Yotti, M. M. Desco, D. Rodriguez-Perez, J. C. Antoranz, J. L. Rojo-Alvarez, D. Garcia, M. A. Garcia-Fernandez, and F. Fernandez-Aviles
Noninvasive Assessment of the Right Ventricular Filling Pressure Gradient
Circulation, August 28, 2007; 116(9): 1015 - 1023.
[Abstract] [Full Text] [PDF]

Home page
 J. Physiol.Home page
C. Marabotti, A. L'Abbate, and R. Bedini
Cardiac changes after SCUBA diving: the evasive shape of right ventricle
J. Physiol., August 15, 2007; 583(1): 405 - 405.
[Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
L. Zhong, R.-S. Tan, D. N. Ghista, E. Y.-K. Ng, L.-P. Chua, and G. S. Kassab
Validation of a novel noninvasive cardiac index of left ventricular contractility in patients
Am J Physiol Heart Circ Physiol, June 1, 2007; 292(6): H2764 - H2772.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. Pasipoularides, M. Shu, A. Shah, A. Tucconi, and D. D. Glower
RV instantaneous intraventricular diastolic pressure and velocity distributions in normal and volume overload awake dog disease models
Am J Physiol Heart Circ Physiol, November 1, 2003; 285(5): H1956 - H1965.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
A. Pasipoularides, M. Shu, A. Shah, M. S. Womack, and D. D. Glower
Diastolic right ventricular filling vortex in normal and volume overload states
Am J Physiol Heart Circ Physiol, April 1, 2003; 284(4): H1064 - H1072.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 1976 by the American Physiological Society.