AJP - Heart Fuel your research with LabChart
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
QUICK SEARCH:   [advanced]


     

Am J Physiol Heart Circ Physiol (May 1, 2003). doi:10.1152/ajpheart.01101.2002
This Article
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
285/2/H841    most recent
01101.2002v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Cooper, H. E.
Right arrow Articles by Clutton-Brock, T. H.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Cooper, H. E.
Right arrow Articles by Clutton-Brock, T. H.
Submitted on December 17, 2002
Accepted on April 21, 2003

CO2-dependent components of sinus arrhythmia from the start of breath-holding in Man

H. E. Cooper1, M. J. Parkes2*, and T. H. Clutton-Brock1

1 School of Sport and Exercise Sciences, University of Birmingham, Bimmingham, United Kingdom
2 Department of Anaesthesia and Intensive Care, University of Birmingham, Birmingham, United Kingdom

* To whom correspondence should be addressed. E-mail: M.J.Parkes{at}bham.ac.uk.

A substantial portion of sinus arrhythmia in conscious humans appears to be caused by the CO2 -dependent central respiratory rhythm. Under some circumstances therefore sinus arrhythmia might indicate the presence of the central respiratory rhythm. Humans can modify voluntarily their central respiratory rhythm (e.g., by pacing breathing, delaying or advancing breaths), but it is not clear what happens to it from the start of breath-holding. We show that sinus arrhythmia persists from the start of breath-holds prolonged by preoxygenation. We show too that some of the frequency components of sinus arrhythmia start within each subject's eupnoeic frequency range and change when end-tidal pCO2 is lowered or raised as we would expect if the central respiratory rhythm continues from the start of breath-holding. We discuss whether sinus arrhythmia can indicate if the central respiratory rhythm continues from the start of breath-holding.




This article has been cited by other articles:


Home page
 RadiologyHome page
R. S. Saleh, S. Patel, M. H. Lee, M. I. Boechat, O. Ratib, C. R. Saraiva, and J. P. Finn
Contrast-enhanced MR Angiography of the Chest and Abdomen with Use of Controlled Apnea in Children
Radiology, June 1, 2007; 243(3): 837 - 846.
[Abstract] [Full Text] [PDF]

Home page
 Exp PhysiolHome page
M. J Parkes
Breath-holding and its breakpoint
Exp Physiol, January 1, 2006; 91(1): 1 - 15.
[Abstract] [Full Text] [PDF]

Home page
 Am. J. Physiol. Heart Circ. Physiol.Home page
H. E. Cooper, T. H. Clutton-Brock, and M. J. Parkes
Contribution of the respiratory rhythm to sinus arrhythmia in normal unanesthetized subjects during positive-pressure mechanical hyperventilation
Am J Physiol Heart Circ Physiol, January 1, 2004; 286(1): H402 - H411.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH
Visit Other APS Journals Online
Copyright © 1976 by the American Physiological Society.