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Am J Physiol Heart Circ Physiol 289: H1826-H1833, 2005. First published June 17, 2005; doi:10.1152/ajpheart.00442.2005
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Three-dimensional systolic kinematics of the right ventricle

Idith Haber,1 Dimitris N. Metaxas,2 Tal Geva,1 and Leon Axel3

1Departments of Cardiology and Cardiac Surgery, Children's Hospital, Boston, Massachusetts; 2Computer Science Department, Rutgers University, Piscataway, New Jersey; and 3Department of Radiology, New York University, New York, New York

Submitted 2 May 2005 ; accepted in final form 16 June 2005

The right ventricle (RV) of the heart is responsible for pumping blood to the lungs. Its kinematics are not as well understood as that of the left ventricle (LV) due to its thin wall and asymmetric geometry. In this study, the combination of tagged MRI and three-dimensional (3-D) image-processing techniques was used to reconstruct 3-D RV-LV motion and deformation. The reconstructed models were used to quantify the 3-D global and local deformation of the ventricles in a set of normal subjects. When compared with the LV, the RV exhibited a similar twisting pattern, a more longitudinal strain pattern, and a greater amount of displacement.

magnetic resonance imaging; myocardial contraction; three-dimentional motion



Address for reprint requests and other correspondence: I. Haber, Children's Hospital, Dept. of Cardiology, 300 Longwood Ave., Bader-2, Boston, MA 02115 (e-mail: idith.haber{at}tch.harvard.edu)




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