Pages H1225–H1234: Shi ZD, Ji XY, Qazi H, Tarbell JM. Interstitial flow promotes vascular fibroblast, myofibroblast, and smooth muscle cell motility in 3-D collagen I via upregulation of MMP-1. Am J Physiol Heart Circ Physiol 297: H1225–H1234, 2009. First published May 22, 2009; doi:10.1152/ajpheart.00369.2009 (http://ajpheart.physiology.org/cgi/content/full/297/4/H1225).
Pages H127–H135: Shi ZD, Ji XY, Berardi DE, Qazi H, Tarbell JM. Interstitial flow induces MMP-1 expression and vascular SMC migration in collagen I gels via an ERK1/2-dependent and c-Jun-mediated mechanism. Am J Physiol Heart Circ Physiol 298: H127–H135, 2010. First published October 30, 2009; doi:10.1152/ajpheart.00732.2009 (http://ajpheart.physiology.org/cgi/content/full/298/1/H127).
In the above articles, it has come to our [the authors'] attention that what we referred to as rat MMP-1 is actually rat MMP-13. Because of confusion in MMP nomenclature, rat interstitial collagenase (genebank locus: M60616) should be recognized as rat MMP-13 and not MMP-1 as currently designated. Human interstitial collagenase is referred to as MMP-1. However, MMP-1 does not exist in the rodent genome, and it has been suggested that its collagenolytic function is mainly performed by rat MMP-13. We were misled by the MMP nomenclature and many other published articles that refer to rat MMP-1. The data we reported on MMP-1 expression should be designated as MMP-13. This change in terminology does not affect our findings or conclusions. We regret any inconvenience this error may have caused.
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