SPECIAL MEDICAL EDITORIALS:

Lior Gepstein, Yair Feld, and Lior Yankelson

Somatic gene and cell therapy strategies for the treatment of cardiac arrhythmias
Am J Physiol Heart Circ Physiol 286: H815-H822, 2004; 10.1152/ajpheart.00962.2003 [Full Text] [PDF]  

INVITED REVIEWS:

Steven M. White, Phillip E. Constantin, and William C. Claycomb

Cardiac physiology at the cellular level: use of cultured HL-1 cardiomyocytes for studies of cardiac muscle cell structure and function
Am J Physiol Heart Circ Physiol 286: H823-H829, 2004; 10.1152/ajpheart.00986.2003 [Abstract] [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Yi Zhun Zhu, Zhong Jing Wang, Yi Chun Zhu, Li Zhang, Reida M. E. Oakley, Chin Wee Chung, Kiat Wee Lim, How Sung Lee, Marie L. Ozoux, Wolfgang Linz, Michael Böhm, and Evi Kostenis

Urotensin II causes fatal circulatory collapse in anesthesized monkeys in vivo: a "vasoconstrictor" with a unique hemodynamic profile
Am J Physiol Heart Circ Physiol 286: H830-H836, 2004. First published November 13, 2003; 10.1152/ajpheart.00406.2003 [Abstract] [Full Text] [PDF]  

ARTICLES:

Peter C. Papageorgiou, Ali Pourdjabbar, Akis A. Amfilochiadis, Eleftherios P. Diamandis, Frans Boomsma, and Daniel H. Osmond

Are cardiovascular and sympathoadrenal effects of human "new pressor protein" preparations attributable to human coagulation -FXIIa?
Am J Physiol Heart Circ Physiol 286: H837-H846, 2004. First published October 23, 2003; 10.1152/ajpheart.00693.2003 [Abstract] [Full Text] [PDF]  

Lisa E. Morrison, Ross J. Whittaker, Robert E. Klepper, Eric F. Wawrousek, and Christopher C. Glembotski

Roles for B-crystallin and HSPB2 in protecting the myocardium from ischemia-reperfusion-induced damage in a KO mouse model
Am J Physiol Heart Circ Physiol 286: H847-H855, 2004. First published October 30, 2003; 10.1152/ajpheart.00715.2003 [Abstract] [Full Text] [PDF]  

Yves Allemann, Martin Rotter, Damian Hutter, Ernst Lipp, Claudio Sartori, Urs Scherrer, and Christian Seiler

Impact of acute hypoxic pulmonary hypertension on LV diastolic function in healthy mountaineers at high altitude
Am J Physiol Heart Circ Physiol 286: H856-H862, 2004. First published November 6, 2003; 10.1152/ajpheart.00518.2003 [Abstract] [Full Text] [PDF]  

Rong Zhang, Thad E. Wilson, Sarah Witkowski, Jian Cui, Craig G. Crandall, and Benjamin D. Levine

Inhibition of nitric oxide synthase does not alter dynamic cerebral autoregulation in humans
Am J Physiol Heart Circ Physiol 286: H863-H869, 2004. First published November 6, 2003; 10.1152/ajpheart.00373.2003 [Abstract] [Full Text] [PDF]  

Marcella Canton, Irina Neverova, Roberta Menabò, Jennifer Van Eyk, and Fabio Di Lisa

Evidence of myofibrillar protein oxidation induced by postischemic reperfusion in isolated rat hearts
Am J Physiol Heart Circ Physiol 286: H870-H877, 2004; 10.1152/ajpheart.00714.2003 [Abstract] [Full Text] [PDF]  

Nanae Hangai-Hoger, Pedro Cabrales, Juan C. Briceño, Amy G. Tsai, and Marcos Intaglietta

Microlymphatic and tissue oxygen tension in the rat mesentery
Am J Physiol Heart Circ Physiol 286: H878-H883, 2004. First published November 20, 2003; 10.1152/ajpheart.00913.2003 [Abstract] [Full Text] [PDF]  

Tine V. Karlsen, Vegard V. Iversen, Erik Forsberg, Lena Kjellén, Rolf K. Reed, and Eli-Anne B. Gjerde

Neurogenic inflammation in mice deficient in heparin-synthesizing enzyme
Am J Physiol Heart Circ Physiol 286: H884-H888, 2004. First published November 6, 2003; 10.1152/ajpheart.00917.2003 [Abstract] [Full Text] [PDF]  

Regis R. Lamberts, Maurice J. J. M. F. Willemsen, Néstor G. Pérez, Pieter Sipkema, and Nico Westerhof

Acute and specific collagen type I degradation increases diastolic and developed tension in perfused rat papillary muscle
Am J Physiol Heart Circ Physiol 286: H889-H894, 2004. First published October 23, 2003; 10.1152/ajpheart.00967.2001 [Abstract] [Full Text] [PDF]  

Kevin D. Monahan and Chester A. Ray

Gender affects calf venous compliance at rest and during baroreceptor unloading in humans
Am J Physiol Heart Circ Physiol 286: H895-H901, 2004. First published November 6, 2003; 10.1152/ajpheart.00719.2003 [Abstract] [Full Text] [PDF]  

Antonio Curcio, Daniele Torella, Giovanni Cuda, Carmela Coppola, Maria Concetta Faniello, Francesco Achille, Viviana G. Russo, Massimo Chiariello, and Ciro Indolfi

Effect of stent coating alone on in vitro vascular smooth muscle cell proliferation and apoptosis
Am J Physiol Heart Circ Physiol 286: H902-H908, 2004. First published October 30, 2003; 10.1152/ajpheart.00130.2003 [Abstract] [Full Text] [PDF]  

Matthew G. Hillebrenner, James C. Eason, and Natalia A. Trayanova

Mechanistic inquiry into decrease in probability of defibrillation success with increase in complexity of preshock reentrant activity
Am J Physiol Heart Circ Physiol 286: H909-H917, 2004. First published November 6, 2003; 10.1152/ajpheart.00492.2003 [Abstract] [Full Text] [PDF]  

Shayn M. Peirce, Richard J. Price, and Thomas C. Skalak

Spatial and temporal control of angiogenesis and arterialization using focal applications of VEGF₁₆₄ and Ang-1
Am J Physiol Heart Circ Physiol 286: H918-H925, 2004. First published November 6, 2003; 10.1152/ajpheart.00833.2003 [Abstract] [Full Text] [PDF]  

Yan Tan, Florence N. Hutchison, and Ayad A. Jaffa

Mechanisms of angiotensin II-induced expression of B₂ kinin receptors
Am J Physiol Heart Circ Physiol 286: H926-H932, 2004; 10.1152/ajpheart.00757.2003 [Abstract] [Full Text] [PDF]  

Xuwan Liu, Chu C. Chua, Jinping Gao, Zhongyi Chen, Cathy L. C. Landy, Ronald Hamdy, and Balvin H. L. Chua

Pifithrin- protects against doxorubicin-induced apoptosis and acute cardiotoxicity in mice
Am J Physiol Heart Circ Physiol 286: H933-H939, 2004; 10.1152/ajpheart.00759.2003 [Abstract] [Full Text] [PDF]  

Jeffrey J. Olearczyk, Alan H. Stephenson, Andrew J. Lonigro, and Randy S. Sprague

Heterotrimeric G protein G_i is involved in a signal transduction pathway for ATP release from erythrocytes
Am J Physiol Heart Circ Physiol 286: H940-H945, 2004. First published November 13, 2003; 10.1152/ajpheart.00677.2003 [Abstract] [Full Text] [PDF]  

Homa Ashrafpour, Ning Huang, Peter C. Neligan, Christopher R. Forrest, Patrick D. Addison, Michael A. Moses, Ronald H. Levine, and Cho Y. Pang

Vasodilator effect and mechanism of action of vascular endothelial growth factor in skin vasculature
Am J Physiol Heart Circ Physiol 286: H946-H954, 2004. First published November 26, 2003; 10.1152/ajpheart.00901.2003 [Abstract] [Full Text] [PDF]  

B. N. Eigel, H. Gursahani, and R. W. Hadley

ROS are required for rapid reactivation of Na⁺/Ca²⁺ exchanger in hypoxic reoxygenated guinea pig ventricular myocytes
Am J Physiol Heart Circ Physiol 286: H955-H963, 2004. First published October 30, 2003; 10.1152/ajpheart.00721.2003 [Abstract] [Full Text] [PDF]  

David W. Stepp, David M. Pollock, and Jefferson C. Frisbee

Low-flow vascular remodeling in the metabolic syndrome X
Am J Physiol Heart Circ Physiol 286: H964-H970, 2004. First published November 26, 2003; 10.1152/ajpheart.00836.2003 [Abstract] [Full Text] [PDF]  

Ariel L. Escobar, Roberta Ribeiro-Costa, Carlos Villalba-Galea, María Elena Zoghbi, Claudia G. Pérez, and Rafael Mejía-Alvarez

Developmental changes of intracellular Ca²⁺ transients in beating rat hearts
Am J Physiol Heart Circ Physiol 286: H971-H978, 2004. First published November 26, 2003; 10.1152/ajpheart.00308.2003 [Abstract] [Full Text] [PDF]  

J. Pieter Versluis, Johannes W. Heslinga, Pieter Sipkema, and Nico Westerhof

Contractile reserve but not tension is reduced in monocrotaline-induced right ventricular hypertrophy
Am J Physiol Heart Circ Physiol 286: H979-H984, 2004. First published October 2, 2003; 10.1152/ajpheart.00536.2002 [Abstract] [Full Text] [PDF]  

Ulrike Kreutzer and Thomas Jue

Role of myoglobin as a scavenger of cellular NO in myocardium
Am J Physiol Heart Circ Physiol 286: H985-H991, 2004; 10.1152/ajpheart.00115.2003 [Abstract] [Full Text] [PDF]  

Jeanne L. Seagard, Caron Dean, Sachin Patel, David J. Rademacher, Francis A. Hopp, William T. Schmeling, and Cecilia J. Hillard

Anandamide content and interaction of endocannabinoid/GABA modulatory effects in the NTS on baroreflex-evoked sympathoinhibition
Am J Physiol Heart Circ Physiol 286: H992-H1000, 2004. First published November 13, 2003; 10.1152/ajpheart.00870.2003 [Abstract] [Full Text] [PDF]  

Xi-Lin Chen, Qiang Zhang, Ruozhi Zhao, and Russell M. Medford

Superoxide, H₂O₂, and iron are required for TNF--induced MCP-1 gene expression in endothelial cells: role of Rac1 and NADPH oxidase
Am J Physiol Heart Circ Physiol 286: H1001-H1007, 2004. First published October 23, 2003; 10.1152/ajpheart.00716.2003 [Abstract] [Full Text] [PDF]  

Ruo L. Chen, Daniel J. Penny, Gottfried Greve, and Max J. Lab

Stretch-induced regional mechanoelectric dispersion and arrhythmia in the right ventricle of anesthetized lambs
Am J Physiol Heart Circ Physiol 286: H1008-H1014, 2004; 10.1152/ajpheart.00724.2003 [Abstract] [Full Text] [PDF]  

T. M. Pocock, R. R. Foster, and D. O. Bates

Evidence of a role for TRPC channels in VEGF-mediated increased vascular permeability in vivo
Am J Physiol Heart Circ Physiol 286: H1015-H1026, 2004. First published October 9, 2003; 10.1152/ajpheart.00826.2003 [Abstract] [Full Text] [PDF]  

Yong-Shan Nan, Guo-Gang Feng, Yoshihiro Hotta, Kimitoshi Nishiwaki, Yasuhiro Shimada, Atsuko Ishikawa, Nakako Kurimoto, Tatsuro Shigei, and Naohisa Ishikawa

Neuropeptide Y enhances permeability across a rat aortic endothelial cell monolayer
Am J Physiol Heart Circ Physiol 286: H1027-H1033, 2004. First published October 23, 2003; 10.1152/ajpheart.00630.2003 [Abstract] [Full Text] [PDF]  

Shivani Mittra, Jean-Marc Hyvelin, Qixian Shan, Fai Tang, and Jean-Pierre Bourreau

Role of cyclooxygenase in ventricular effects of adrenomedullin: is adrenomedullin a double-edged sword in sepsis?
Am J Physiol Heart Circ Physiol 286: H1034-H1042, 2004; 10.1152/ajpheart.00337.2003 [Abstract] [Full Text] [PDF]  

Nikolaos M. Tsoukias, Mahendra Kavdia, and Aleksander S. Popel

A theoretical model of nitric oxide transport in arterioles: frequency- vs. amplitude-dependent control of cGMP formation
Am J Physiol Heart Circ Physiol 286: H1043-H1056, 2004. First published October 30, 2003; 10.1152/ajpheart.00525.2003 [Abstract] [Full Text] [PDF]  

Jerome W. Breslin and Sarah Y. Yuan

Involvement of RhoA and Rho kinase in neutrophil-stimulated endothelial hyperpermeability
Am J Physiol Heart Circ Physiol 286: H1057-H1062, 2004. First published November 20, 2003; 10.1152/ajpheart.00841.2003 [Abstract] [Full Text] [PDF]  

Jin-Jiang Pang, Rong-Kun Xu, Xiang-Bin Xu, Ji-Min Cao, Chao Ni, Wen-Ling Zhu, Kamlesh Asotra, Meng-Chin Chen, and Chen Chen

Hexarelin protects rat cardiomyocytes from angiotensin II-induced apoptosis in vitro
Am J Physiol Heart Circ Physiol 286: H1063-H1069, 2004. First published November 13, 2003; 10.1152/ajpheart.00648.2003 [Abstract] [Full Text] [PDF]  

Fumito Ichinose, Kenneth D. Bloch, Justina C. Wu, Ryuji Hataishi, H. Thomas Aretz, Michael H. Picard, and Marielle Scherrer-Crosbie

Pressure overload-induced LV hypertrophy and dysfunction in mice are exacerbated by congenital NOS3 deficiency
Am J Physiol Heart Circ Physiol 286: H1070-H1075, 2004. First published November 26, 2003; 10.1152/ajpheart.00940.2003 [Abstract] [Full Text] [PDF]  

Paul J. Fadel, Hakan S. Orer, Susan M. Barman, Wanpen Vongpatanasin, Ronald G. Victor, and Gerard L. Gebber

Fractal properties of human muscle sympathetic nerve activity
Am J Physiol Heart Circ Physiol 286: H1076-H1087, 2004. First published November 6, 2003; 10.1152/ajpheart.00577.2003 [Abstract] [Full Text] [PDF]  

Kevin D. Luykenaar, Suzanne E. Brett, Bin Nan Wu, William B. Wiehler, and Donald G. Welsh

Pyrimidine nucleotides suppress K_DR currents and depolarize rat cerebral arteries by activating Rho kinase
Am J Physiol Heart Circ Physiol 286: H1088-H1100, 2004. First published October 30, 2003; 10.1152/ajpheart.00903.2003 [Abstract] [Full Text] [PDF]  

Jian Cui, Rong Zhang, Thad E. Wilson, and Craig G. Crandall

Spectral analysis of muscle sympathetic nerve activity in heat-stressed humans
Am J Physiol Heart Circ Physiol 286: H1101-H1106, 2004. First published November 20, 2003; 10.1152/ajpheart.00790.2003 [Abstract] [Full Text] [PDF]  

Galyna Dubrovska, Stefan Verlohren, Friedrich C. Luft, and Maik Gollasch

Mechanisms of ADRF release from rat aortic adventitial adipose tissue
Am J Physiol Heart Circ Physiol 286: H1107-H1113, 2004. First published November 26, 2003; 10.1152/ajpheart.00656.2003 [Abstract] [Full Text] [PDF]  

Daphne Merkus, Birgit Houweling, Alisina Zarbanoui, and Dirk J. Duncker

Interaction between prostanoids and nitric oxide in regulation of systemic, pulmonary, and coronary vascular tone in exercising swine
Am J Physiol Heart Circ Physiol 286: H1114-H1123, 2004. First published October 16, 2003; 10.1152/ajpheart.00477.2003 [Abstract] [Full Text] [PDF]  

Dacia L. Hunton, LuYun Zou, Yi Pang, and Richard B. Marchase

Adult rat cardiomyocytes exhibit capacitative calcium entry
Am J Physiol Heart Circ Physiol 286: H1124-H1132, 2004. First published November 20, 2003; 10.1152/ajpheart.00162.2003 [Abstract] [Full Text] [PDF]  

Ashwani Khanna

Concerted effect of transforming growth factor-, cyclin inhibitor p21, and c-myc on smooth muscle cell proliferation
Am J Physiol Heart Circ Physiol 286: H1133-H1140, 2004; 10.1152/ajpheart.00462.2003 [Abstract] [Full Text] [PDF]  

John D. Parker and Jake J. Thiessen

Increased endothelin-1 production in patients with chronic heart failure
Am J Physiol Heart Circ Physiol 286: H1141-H1145, 2004; 10.1152/ajpheart.00239.2001 [Abstract] [Full Text] [PDF]  

Jo El J. Schultz, Betty J. Glascock, Sandra A. Witt, Michelle L. Nieman, Kalpana J. Nattamai, Lynne H. Liu, John N. Lorenz, Gary E. Shull, Thomas R. Kimball, and Muthu Periasamy

Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity
Am J Physiol Heart Circ Physiol 286: H1146-H1153, 2004. First published November 20, 2003; 10.1152/ajpheart.00720.2003 [Abstract] [Full Text] [PDF]  

Vladimir E. Bondarenko, Glenna C. L. Bett, and Randall L. Rasmusson

A model of graded calcium release and L-type Ca²⁺ channel inactivation in cardiac muscle
Am J Physiol Heart Circ Physiol 286: H1154-H1169, 2004. First published November 20, 2003; 10.1152/ajpheart.00168.2003 [Abstract] [Full Text] [PDF]  

Terry B. J. Kuo, Ching J. Lai, Fu-Zen Shaw, Chi-Wan Lai, and Cheryl C. H. Yang

Sleep-related sympathovagal imbalance in SHR
Am J Physiol Heart Circ Physiol 286: H1170-H1176, 2004. First published November 20, 2003; 10.1152/ajpheart.00418.2003 [Abstract] [Full Text] [PDF]  

W. Ross Tracey, Judith L. Treadway, William P. Magee, Jill C. Sutt, R. Kirk McPherson, Carolyn B. Levy, Donald E. Wilder, Li J. Yu, Yue Chen, Ravi M. Shanker, Alison K. Mutchler, Andrew H. Smith, David M. Flynn, and Delvin R. Knight

Cardioprotective effects of ingliforib, a novel glycogen phosphorylase inhibitor
Am J Physiol Heart Circ Physiol 286: H1177-H1184, 2004. First published November 13, 2003; 10.1152/ajpheart.00652.2003 [Abstract] [Full Text] [PDF]  

Saumya Sharma, Heinrich Taegtmeyer, Julia Adrogue, Peter Razeghi, Shiraj Sen, Kholiswa Ngumbela, and M. Faadiel Essop

Dynamic changes of gene expression in hypoxia-induced right ventricular hypertrophy
Am J Physiol Heart Circ Physiol 286: H1185-H1192, 2004. First published November 20, 2003; 10.1152/ajpheart.00916.2003 [Abstract] [Full Text] [PDF]  

Jian Huang, Jack M. Rogers, Cheryl R. Killingsworth, Karan P. Singh, William M. Smith, and Raymond E. Ideker

Evolution of activation patterns during long-duration ventricular fibrillation in dogs
Am J Physiol Heart Circ Physiol 286: H1193-H1200, 2004; 10.1152/ajpheart.00773.2003 [Abstract] [Full Text] [PDF]  

Dongchoon Ahn, Linda Cheng, Chanil Moon, Harold Spurgeon, Edward G. Lakatta, and Mark I. Talan

Induction of myocardial infarcts of a predictable size and location by branch pattern probability-assisted coronary ligation in C57BL/6 mice
Am J Physiol Heart Circ Physiol 286: H1201-H1207, 2004; 10.1152/ajpheart.00862.2003 [Abstract] [Full Text] [PDF]  

Shinji Ishizaka, Richard E. Sievers, Bo-Qing Zhu, Manoj C. Rodrigo, Shuji Joho, Elyse Foster, Paul C. Simpson, and William Grossman

New technique for measurement of left ventricular pressure in conscious mice
Am J Physiol Heart Circ Physiol 286: H1208-H1215, 2004. First published October 16, 2003; 10.1152/ajpheart.00011.2003 [Abstract] [Full Text] [PDF]  

Julian M. Stewart, Marvin S. Medow, Leslie D. Montgomery, and Kenneth McLeod

Decreased skeletal muscle pump activity in patients with postural tachycardia syndrome and low peripheral blood flow
Am J Physiol Heart Circ Physiol 286: H1216-H1222, 2004. First published October 23, 2003; 10.1152/ajpheart.00738.2003 [Abstract] [Full Text] [PDF]  

Juan Carlos Briceño, Pedro Cabrales, Amy G. Tsai, and Marcos Intaglietta

Radial displacement of red blood cells during hemodilution and the effect on arteriolar oxygen profile
Am J Physiol Heart Circ Physiol 286: H1223-H1228, 2004. First published November 13, 2003; 10.1152/ajpheart.00666.2003 [Abstract] [Full Text] [PDF]  

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