TRANSLATIONAL PHYSIOLOGY:

Dean C.-S. Tai, Bryan J. Caldwell, Ian J. LeGrice, Darren A. Hooks, Andrew J. Pullan, and Bruce H. Smaill

Correction of motion artifact in transmembrane voltage-sensitive fluorescent dye emission in hearts
Am J Physiol Heart Circ Physiol 287: H985-H993, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00574.2003 [Abstract] [Full Text] [PDF]  

ARTICLES:

Akinori Ueda, Masaki Koga, Mariko Ikeda, Susumu Kudo, and Kazuo Tanishita

Effect of shear stress on microvessel network formation of endothelial cells with in vitro three-dimensional model
Am J Physiol Heart Circ Physiol 287: H994-H1002, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00400.2003 [Abstract] [Full Text] [PDF]  

Keisuke Kawai, Fuzhong Qin, Junya Shite, Weike Mao, Shuji Fukuoka, and Chang-seng Liang

Importance of antioxidant and antiapoptotic effects of -receptor blockers in heart failure therapy
Am J Physiol Heart Circ Physiol 287: H1003-H1012, 2004. First published April 22, 2004; doi:10.1152/ajpheart.00797.2003 [Abstract] [Full Text] [PDF]  

Ehsan Y. Davani, Delbert R. Dorscheid, Cheng-Han Lee, Cornelis van Breemen, and Keith R. Walley

Novel regulatory mechanism of cardiomyocyte contractility involving ICAM-1 and the cytoskeleton
Am J Physiol Heart Circ Physiol 287: H1013-H1022, 2004. First published April 15, 2004; doi:10.1152/ajpheart.01177.2003 [Abstract] [Full Text] [PDF]  

Pierre Bonnet, Sébastien Bonnet, Julien Boissière, Jean-Loïc Le Net, Mathieu Gautier, Eric Dumas de la Roque, and Véronique Eder

Chronic hypoxia induces nonreversible right ventricle dysfunction and dysplasia in rats
Am J Physiol Heart Circ Physiol 287: H1023-H1028, 2004; doi:10.1152/ajpheart.00802.2003 [Abstract] [Full Text] [PDF]  

Scott A. Grandy, Eileen M. Denovan-Wright, Gregory R. Ferrier, and Susan E. Howlett

Overexpression of human ₂-adrenergic receptors increases gain of excitation-contraction coupling in mouse ventricular myocytes
Am J Physiol Heart Circ Physiol 287: H1029-H1038, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00814.2003 [Abstract] [Full Text] [PDF]  

Matthias Spindler, Klaus Meyer, Hinrik Strömer, Andrea Leupold, Ernest Boehm, Helga Wagner, and Stefan Neubauer

Creatine kinase-deficient hearts exhibit increased susceptibility to ischemia-reperfusion injury and impaired calcium homeostasis
Am J Physiol Heart Circ Physiol 287: H1039-H1045, 2004. First published April 22, 2004; doi:10.1152/ajpheart.01016.2003 [Abstract] [Full Text] [PDF]  

Wen Dun, Shigeo Baba, Takuya Yagi, and Penelope A. Boyden

Dynamic remodeling of K⁺ and Ca²⁺ currents in cells that survived in the epicardial border zone of canine healed infarcted heart
Am J Physiol Heart Circ Physiol 287: H1046-H1054, 2004. First published April 15, 2004; doi:10.1152/ajpheart.00082.2004 [Abstract] [Full Text] [PDF]  

Yan Burelle, Richard B. Wambolt, Mark Grist, Hannah L. Parsons, Jeffrey C. F. Chow, Christine Antler, Arend Bonen, Angelica Keller, George A. Dunaway, Kirill M. Popov, Peter W. Hochachka, and Michael F. Allard

Regular exercise is associated with a protective metabolic phenotype in the rat heart
Am J Physiol Heart Circ Physiol 287: H1055-H1063, 2004. First published April 22, 2004; doi:10.1152/ajpheart.00925.2003 [Abstract] [Full Text] [PDF]  

Takayuki Matsumoto, Kentaro Wakabayashi, Tsuneo Kobayashi, and Katsuo Kamata

Diabetes-related changes in cAMP-dependent protein kinase activity and decrease in relaxation response in rat mesenteric artery
Am J Physiol Heart Circ Physiol 287: H1064-H1071, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00069.2004 [Abstract] [Full Text] [PDF]  

Shuichi Kobayashi, Yoshiro Yoshikawa, Susumu Sakata, Chikako Takenaka, Hiroji Hagihara, Yoshimi Ohga, Takehisa Abe, Shigeki Taniguchi, and Miyako Takaki

Left ventricular mechanoenergetics after hyperpolarized cardioplegic arrest by nicorandil and after depolarized cardioplegic arrest by KCl
Am J Physiol Heart Circ Physiol 287: H1072-H1080, 2004. First published April 22, 2004; doi:10.1152/ajpheart.00133.2004 [Abstract] [Full Text] [PDF]  

Tina M. Griffin, Tina V. Valdez, and Ruben Mestril

Radicicol activates heat shock protein expression and cardioprotection in neonatal rat cardiomyocytes
Am J Physiol Heart Circ Physiol 287: H1081-H1088, 2004. First published April 29, 2004; doi:10.1152/ajpheart.00921.2003 [Abstract] [Full Text] [PDF]  

Fan Zhang, Mong-Heng Wang, Ji-Shi Wang, Barbara Zand, V. Raj Gopal, John R. Falck, Michal Laniado-Schwartzman, and Alberto Nasjletti

Transfection of CYP4A1 cDNA decreases diameter and increases responsiveness of gracilis muscle arterioles to constrictor stimuli
Am J Physiol Heart Circ Physiol 287: H1089-H1095, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00627.2003 [Abstract] [Full Text] [PDF]  

Alexander Yang, Dimitry Sonin, Larry Jones, William H. Barry, and Bruce T. Liang

A beneficial role of cardiac P2X₄ receptors in heart failure: rescue of the calsequestrin overexpression model of cardiomyopathy
Am J Physiol Heart Circ Physiol 287: H1096-H1103, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00079.2004 [Abstract] [Full Text] [PDF]  

Yu Chen, André-Patrick Arrigo, and R. William Currie

Heat shock treatment suppresses angiotensin II-induced activation of NF-B pathway and heart inflammation: a role for IKK depletion by heat shock?
Am J Physiol Heart Circ Physiol 287: H1104-H1114, 2004. First published April 15, 2004; doi:10.1152/ajpheart.00102.2004 [Abstract] [Full Text] [PDF]  

Virginia M. Miller, George Rodgers, Jon A. Charlesworth, Brenda Kirkland, Sandra R. Severson, Todd E. Rasmussen, Marineh Yagubyan, Jeri C. Rodgers, Franklin R. Cockerill, III, Robert L. Folk, Ewa Rzewuska-Lech, Vivek Kumar, Gerard Farell-Baril, and John C. Lieske

Evidence of nanobacterial-like structures in calcified human arteries and cardiac valves
Am J Physiol Heart Circ Physiol 287: H1115-H1124, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00075.2004 [Abstract] [Full Text] [PDF]  

Yigang Wang, Nauman Ahmad, Mitsuhiro Kudo, and Muhammad Ashraf

Contribution of Akt and endothelial nitric oxide synthase to diazoxide-induced late preconditioning
Am J Physiol Heart Circ Physiol 287: H1125-H1131, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00183.2004 [Abstract] [Full Text] [PDF]  

Ulrich K. M. Decking, Vinay M. Pai, Eric Bennett, Joni L. Taylor, Christian D. Fingas, Klaus Zanger, Han Wen, and Robert S. Balaban

High-resolution imaging reveals a limit in spatial resolution of blood flow measurements by microspheres
Am J Physiol Heart Circ Physiol 287: H1132-H1140, 2004. First published April 29, 2004; doi:10.1152/ajpheart.00119.2004 [Abstract] [Full Text] [PDF]  

Jon J. Andresen, Frank M. Faraci, and Donald D. Heistad

Vasomotor responses in MnSOD-deficient mice
Am J Physiol Heart Circ Physiol 287: H1141-H1148, 2004; doi:10.1152/ajpheart.01215.2003 [Abstract] [Full Text] [PDF]  

C. M. Loughrey, G. L. Smith, and K. E. MacEachern

Comparison of Ca²⁺ release and uptake characteristics of the sarcoplasmic reticulum in isolated horse and rabbit cardiomyocytes
Am J Physiol Heart Circ Physiol 287: H1149-H1159, 2004. First published April 29, 2004; doi:10.1152/ajpheart.00060.2004 [Abstract] [Full Text] [PDF]  

Bing S. Huang, Bruce N. Van Vliet, and Frans H. H. Leenen

Increases in CSF [Na⁺] precede the increases in blood pressure in Dahl S rats and SHR on a high-salt diet
Am J Physiol Heart Circ Physiol 287: H1160-H1166, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00126.2004 [Abstract] [Full Text] [PDF]  

Matthias Schmitt, Ahmad Qasem, Carmel McEniery, Ian B. Wilkinson, Vicki Tatarinoff, Kate Noble, John Klemes, Nicola Payne, Michael P. Frenneaux, John Cockcroft, and Albert Avolio

Role of natriuretic peptides in regulation of conduit artery distensibility
Am J Physiol Heart Circ Physiol 287: H1167-H1171, 2004; doi:10.1152/ajpheart.00101.2004 [Abstract] [Full Text] [PDF]  

Paolo Marino, Giuseppe Faggian, Paolo Bertolini, Alessandro Mazzucco, and William C. Little

Early mitral deceleration and left atrial stiffness
Am J Physiol Heart Circ Physiol 287: H1172-H1178, 2004. First published April 15, 2004; doi:10.1152/ajpheart.00051.2004 [Abstract] [Full Text] [PDF]  

Rebecca H. Ritchie, A. C. Rosenkranz, L. P. Huynh, T. Stephenson, D. M. Kaye, and G. J. Dusting

Activation of IP prostanoid receptors prevents cardiomyocyte hypertrophy via cAMP-dependent signaling
Am J Physiol Heart Circ Physiol 287: H1179-H1185, 2004. First published April 8, 2004; doi:10.1152/ajpheart.00725.2003 [Abstract] [Full Text] [PDF]  

Ruiqian Wan, Simonetta Camandola, and Mark P. Mattson

Dietary supplementation with 2-deoxy-D-glucose improves cardiovascular and neuroendocrine stress adaptation in rats
Am J Physiol Heart Circ Physiol 287: H1186-H1193, 2004; doi:10.1152/ajpheart.00932.2003 [Abstract] [Full Text] [PDF]  

Adelino F. Leite-Moreira and Carmen Brás-Silva

Inotropic effects of ET_B receptor stimulation and their modulation by endocardial endothelium, NO, and prostaglandins
Am J Physiol Heart Circ Physiol 287: H1194-H1199, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00563.2003 [Abstract] [Full Text] [PDF]  

Afaf Absood, Akira Furutani, Tsutomu Kawamura, and Linda M. Graham

A comparison of oxidized LDL-induced collagen secretion by graft and aortic SMCs: role of PDGF
Am J Physiol Heart Circ Physiol 287: H1200-H1206, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00228.2004 [Abstract] [Full Text] [PDF]  

Ines Hasanbasic, Jessica Cuerquis, Brian Varnum, and Mark D. Blostein

Intracellular signaling pathways involved in Gas6-Axl-mediated survival of endothelial cells
Am J Physiol Heart Circ Physiol 287: H1207-H1213, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00020.2004 [Abstract] [Full Text] [PDF]  

José A. L. Calbet, Göran Rådegran, Robert Boushel, Hans Søndergaard, Bengt Saltin, and Peter D. Wagner

Plasma volume expansion does not increase maximal cardiac output or VO_{2 max} in lowlanders acclimatized to altitude
Am J Physiol Heart Circ Physiol 287: H1214-H1224, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00840.2003 [Abstract] [Full Text] [PDF]  

Lucilla D. Monti, Claudio Landoni, Emanuela Setola, Elena Galluccio, Pietro Lucotti, Emilia P. Sandoli, Anna Origgi, Giovanni Lucignani, PierMarco Piatti, and Ferruccio Fazio

Myocardial insulin resistance associated with chronic hypertriglyceridemia and increased FFA levels in Type 2 diabetic patients
Am J Physiol Heart Circ Physiol 287: H1225-H1231, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00629.2003 [Abstract] [Full Text] [PDF]  

Sassan Hafizi, Xuemin Wang, Adrian H. Chester, Magdi H. Yacoub, and Christopher G. Proud

ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells
Am J Physiol Heart Circ Physiol 287: H1232-H1238, 2004; doi:10.1152/ajpheart.00040.2004 [Abstract] [Full Text] [PDF]  

Eleonora Savio-Galimberti, Patrícia Dos Santos Costa, Antônio Carlos Campos de Carvalho, and Jorge Emilio Ponce-Hornos

Mechanical and energetic effects of chronic chagasic patients' antibodies on rat myocardium
Am J Physiol Heart Circ Physiol 287: H1239-H1245, 2004. First published May 20, 2004; doi:10.1152/ajpheart.01155.2003 [Abstract] [Full Text] [PDF]  

C. Chouabe, E. Ricci, J. Amsellem, S. Blaineau, Y. Dalmaz, R. Favier, J.-M. Pequignot, and R. Bonvallet

Effects of aging on the cardiac remodeling induced by chronic high-altitude hypoxia in rat
Am J Physiol Heart Circ Physiol 287: H1246-H1253, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00199.2004 [Abstract] [Full Text] [PDF]  

Shu-Hui Juan, Jin-Jer Chen, Cheng-Hsien Chen, Heng Lin, Ching-Feng Cheng, Ju-Chi Liu, Ming-Hsiung Hsieh, Yen-Ling Chen, Hung-Hsing Chao, Tso-Hsiao Chen, Paul Chan, and Tzu-Hurng Cheng

17-Estradiol inhibits cyclic strain-induced endothelin-1 gene expression within vascular endothelial cells
Am J Physiol Heart Circ Physiol 287: H1254-H1261, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00723.2003 [Abstract] [Full Text] [PDF]  

Brian A. Mullan, Ciaran N. Ennis, Howard J. P. Fee, Ian S. Young, and David R. McCance

Protective effects of ascorbic acid on arterial hemodynamics during acute hyperglycemia
Am J Physiol Heart Circ Physiol 287: H1262-H1268, 2004. First published April 15, 2004; doi:10.1152/ajpheart.00153.2003 [Abstract] [Full Text] [PDF]  

Brian S. Palmer, Paul F. Klawitter, Peter J. Reiser, and Mark G. Angelos

Degradation of rat cardiac troponin I during ischemia independent of reperfusion
Am J Physiol Heart Circ Physiol 287: H1269-H1275, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00149.2004 [Abstract] [Full Text] [PDF]  

Lihong Yin, Harold Bien, and Emilia Entcheva

Scaffold topography alters intracellular calcium dynamics in cultured cardiomyocyte networks
Am J Physiol Heart Circ Physiol 287: H1276-H1285, 2004. First published April 22, 2004; doi:10.1152/ajpheart.01120.2003 [Abstract] [Full Text] [PDF]  

Sarah J. Canyon and Geoffrey P. Dobson

Protection against ventricular arrhythmias and cardiac death using adenosine and lidocaine during regional ischemia in the in vivo rat
Am J Physiol Heart Circ Physiol 287: H1286-H1295, 2004; doi:10.1152/ajpheart.00273.2004 [Abstract] [Full Text] [PDF]  

Rongqian Wu, Mian Zhou, Xiaoxuan Cui, H. Hank Simms, and Ping Wang

Upregulation of cardiovascular ghrelin receptor occurs in the hyperdynamic phase of sepsis
Am J Physiol Heart Circ Physiol 287: H1296-H1302, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00852.2003 [Abstract] [Full Text] [PDF]  

David Engel, Ronald Peshock, Robert C. Armstong, Natarajan Sivasubramanian, and Douglas L. Mann

Cardiac myocyte apoptosis provokes adverse cardiac remodeling in transgenic mice with targeted TNF overexpression
Am J Physiol Heart Circ Physiol 287: H1303-H1311, 2004; doi:10.1152/ajpheart.00053.2004 [Abstract] [Full Text] [PDF]  

Jianhua Li

Central integration of muscle reflex and arterial baroreflex in midbrain periaqueductal gray: roles of GABA and NO
Am J Physiol Heart Circ Physiol 287: H1312-H1318, 2004. First published April 15, 2004; doi:10.1152/ajpheart.00163.2004 [Abstract] [Full Text] [PDF]  

Julian M. Stewart and Leslie D. Montgomery

Regional blood volume and peripheral blood flow in postural tachycardia syndrome
Am J Physiol Heart Circ Physiol 287: H1319-H1327, 2004. First published April 29, 2004; doi:10.1152/ajpheart.00086.2004 [Abstract] [Full Text] [PDF]  

Edward O. McFalls, MingXiao Hou, Robert J. Bache, Aaron Best, David Marx, Joseph Sikora, and Herbert B. Ward

Activation of p38 MAPK and increased glucose transport in chronic hibernating swine myocardium
Am J Physiol Heart Circ Physiol 287: H1328-H1334, 2004; doi:10.1152/ajpheart.01188.2003 [Abstract] [Full Text] [PDF]  

Martin A. Zulliger, Alexander Rachev, and Nikos Stergiopulos

A constitutive formulation of arterial mechanics including vascular smooth muscle tone
Am J Physiol Heart Circ Physiol 287: H1335-H1343, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00094.2004 [Abstract] [Full Text] [PDF]  

Malgorzata Czarny and Jan E. Schnitzer

Neutral sphingomyelinase inhibitor scyphostatin prevents and ceramide mimics mechanotransduction in vascular endothelium
Am J Physiol Heart Circ Physiol 287: H1344-H1352, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00222.2004 [Abstract] [Full Text] [PDF]  

David J. C. Alders, A. B. Johan Groeneveld, Frans J. J. de Kanter, and Johannes H. G. M. van Beek

Myocardial O₂ consumption in porcine left ventricle is heterogeneously distributed in parallel to heterogeneous O₂ delivery
Am J Physiol Heart Circ Physiol 287: H1353-H1361, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00338.2003 [Abstract] [Full Text] [PDF]  

Alexander Sasse, Zhaoping Ding, Martina Wallich, Axel Gödecke, and Jürgen Schrader

Vascular transfer of adenovirus is augmented by nitric oxide in the rat heart
Am J Physiol Heart Circ Physiol 287: H1362-H1368, 2004. First published May 6, 2004; doi:10.1152/ajpheart.00193.2003 [Abstract] [Full Text] [PDF]  

Ravi Ramani, Michael Mathier, Ping Wang, Gregory Gibson, Sandra Tögel, Jennifer Dawson, Anthony Bauer, Sean Alber, Simon C. Watkins, Charles F. McTiernan, and Arthur M. Feldman

Inhibition of tumor necrosis factor receptor-1-mediated pathways has beneficial effects in a murine model of postischemic remodeling
Am J Physiol Heart Circ Physiol 287: H1369-H1377, 2004; doi:10.1152/ajpheart.00641.2003 [Abstract] [Full Text] [PDF]  

Vladimir E. Bondarenko, Gyula P. Szigeti, Glenna C. L. Bett, Song-Jung Kim, and Randall L. Rasmusson

Computer model of action potential of mouse ventricular myocytes
Am J Physiol Heart Circ Physiol 287: H1378-H1403, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00185.2003 [Abstract] [Full Text] [PDF]  

Dan P. Stephens, Adham R. Saad, Lee Ann T. Bennett, Wojciech A. Kosiba, and John M. Johnson

Neuropeptide Y antagonism reduces reflex cutaneous vasoconstriction in humans
Am J Physiol Heart Circ Physiol 287: H1404-H1409, 2004. First published May 27, 2004; doi:10.1152/ajpheart.00061.2004 [Abstract] [Full Text] [PDF]  

Kathryn E. Richards, Dimitri Deserranno, Erwan Donal, Neil L. Greenberg, James D. Thomas, and Mario J. Garcia

Influence of structural geometry on the severity of bicuspid aortic stenosis
Am J Physiol Heart Circ Physiol 287: H1410-H1416, 2004. First published April 29, 2004; doi:10.1152/ajpheart.00264.2003 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Xin Dong, Jinbao Liu, Hanqiao Zheng, Joseph W. Glasford, Wei Huang, Quan Hai Chen, Niels R. Harden, Faqian Li, A. Martin Gerdes, and Xuejun Wang

In situ dynamically monitoring the proteolytic function of the ubiquitin-proteasome system in cultured cardiac myocytes
Am J Physiol Heart Circ Physiol 287: H1417-H1425, 2004. First published April 22, 2004; doi:10.1152/ajpheart.01233.2003 [Abstract] [Full Text] [PDF]  

Craig J. Hartley, Anilkumar K. Reddy, Sridhar Madala, Mark L. Entman, Lloyd H. Michael, and George E. Taffet

Noninvasive ultrasonic measurement of arterial wall motion in mice
Am J Physiol Heart Circ Physiol 287: H1426-H1432, 2004; doi:10.1152/ajpheart.01185.2003 [Abstract] [Full Text] [PDF]  

CORRIGENDA:

Corrigendum
Am J Physiol Heart Circ Physiol 287: H1433-H1433, 2004; doi:10.1152/ajpheart.00642.2004 [Full Text] [PDF]  

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