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Contents: Volume 287, Issue 4
October 2004
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ARTICLES:

Birgit Bölck, Götz Münch, Peter Mackenstein, Martin Hellmich, Ingo Hirsch, Hannes Reuter, Nadja Hattebuhr, Hans-Jörg Weig, Martin Ungerer, Klara Brixius, and Robert H. G. Schwinger
Na+/Ca2+ exchanger overexpression impairs frequency- and ouabain-dependent cell shortening in adult rat cardiomyocytes
Am J Physiol Heart Circ Physiol 287: H1435-H1445, 2004. First published May 27, 2004; doi:10.1152/ajpheart.00397.2003 [Abstract] [Full Text] [PDF]  

Lisa M. Hunt, Emily W. Hogeland, Maria K. Henry, and Steven J. Swoap
Hypotension and bradycardia during caloric restriction in mice are independent of salt balance and do not require ANP receptor
Am J Physiol Heart Circ Physiol 287: H1446-H1451, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00353.2004 [Abstract] [Full Text] [PDF]  

Xi-Lin Chen, Janice Y. Grey, Suzanne Thomas, Fei-Hua Qiu, Russell M. Medford, Martin A. Wasserman, and Charles Kunsch
Sphingosine kinase-1 mediates TNF-{alpha}-induced MCP-1 gene expression in endothelial cells: upregulation by oscillatory flow
Am J Physiol Heart Circ Physiol 287: H1452-H1458, 2004. First published June 10, 2004; doi:10.1152/ajpheart.01101.2003 [Abstract] [Full Text] [PDF]  

Ebrahim Barkoudah, Jonathan H. Jaggar, and Charles W. Leffler
The permissive role of endothelial NO in CO-induced cerebrovascular dilation
Am J Physiol Heart Circ Physiol 287: H1459-H1465, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00369.2004 [Abstract] [Full Text] [PDF]  

B. N. Eigel, H. Gursahani, and R. W. Hadley
Na+/Ca2+ exchanger plays a key role in inducing apoptosis after hypoxia in cultured guinea pig ventricular myocytes
Am J Physiol Heart Circ Physiol 287: H1466-H1475, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00874.2003 [Abstract] [Full Text] [PDF]  

Masaki Okajima, Robert Parent, Eric Thorin, and Michel Lavallée
Pathophysiological plasma ET-1 levels antagonize {beta}-adrenergic dilation of coronary resistance vessels in conscious dogs
Am J Physiol Heart Circ Physiol 287: H1476-H1483, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00297.2004 [Abstract] [Full Text] [PDF]  

Ganapathy Jagatheesan, Sudarsan Rajan, Natalia Petrashevskaya, Arnold Schwartz, Greg Boivin, Grace Arteaga, Pieter P. de Tombe, R. John Solaro, and David F. Wieczorek
Physiological significance of troponin T binding domains in striated muscle tropomyosin
Am J Physiol Heart Circ Physiol 287: H1484-H1494, 2004. First published June 10, 2004; doi:10.1152/ajpheart.01112.2003 [Abstract] [Full Text] [PDF]  

Liming Jin, Zhekang Ying, and R. Clinton Webb
Activation of Rho/Rho kinase signaling pathway by reactive oxygen species in rat aorta
Am J Physiol Heart Circ Physiol 287: H1495-H1500, 2004; doi:10.1152/ajpheart.01006.2003 [Abstract] [Full Text] [PDF]  

H.V.O. Carswell, I.M. Macrae, L. Gallagher, E. Harrop, and K.J. Horsburgh
Neuroprotection by a selective estrogen receptor {beta} agonist in a mouse model of global ischemia
Am J Physiol Heart Circ Physiol 287: H1501-H1504, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00227.2004 [Abstract] [Full Text] [PDF]  

Zhao-Jun Fu, Man-Jiang Xie, Li-Fan Zhang, Hong-Wei Cheng, and Jin Ma
Differential activation of potassium channels in cerebral and hindquarter arteries of rats during simulated microgravity
Am J Physiol Heart Circ Physiol 287: H1505-H1515, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00143.2004 [Abstract] [Full Text] [PDF]  

Thomas H. Langenickel, Ines Pagel, Jens Buttgereit, Katja Tenner, Maren Lindner, Rainer Dietz, Roland Willenbrock, and Michael Bader
Rat corin gene: molecular cloning and reduced expression in experimental heart failure
Am J Physiol Heart Circ Physiol 287: H1516-H1521, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00947.2003 [Abstract] [Full Text] [PDF]  

Chris J. Pemberton, Heikki Tokola, Zsolt Bagi, Akos Koller, Juhani Pöntinen, Antti Ola, Olli Vuolteenaho, István Szokodi, and Heikki Ruskoaho
Ghrelin induces vasoconstriction in the rat coronary vasculature without altering cardiac peptide secretion
Am J Physiol Heart Circ Physiol 287: H1522-H1529, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00193.2004 [Abstract] [Full Text] [PDF]  

Demetra D. Christou, Pamela Parker Jones, Annemarie E. Pimentel, and Douglas R. Seals
Increased abdominal-to-peripheral fat distribution contributes to altered autonomic-circulatory control with human aging
Am J Physiol Heart Circ Physiol 287: H1530-H1537, 2004. First published June 3, 2004; doi:10.1152/ajpheart.00322.2004 [Abstract] [Full Text] [PDF]  

Margaret P. Chandler, Janos Kerner, Hazel Huang, Edwin Vazquez, Aneta Reszko, Wenjun Z. Martini, Charles L. Hoppel, Makoto Imai, Sharad Rastogi, Hani N. Sabbah, and William C. Stanley
Moderate severity heart failure does not involve a downregulation of myocardial fatty acid oxidation
Am J Physiol Heart Circ Physiol 287: H1538-H1543, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00281.2004 [Abstract] [Full Text] [PDF]  

George J. Christ, Nancy Day, Cristian Santizo, Yoshi Sato, Weixin Zhao, Theresa Sclafani, Ron Bakal, Masha Salman, Kelvin Davies, and Arnold Melman
Intracorporal injection of hSlo cDNA restores erectile capacity in STZ-diabetic F-344 rats in vivo
Am J Physiol Heart Circ Physiol 287: H1544-H1553, 2004; doi:10.1152/ajpheart.00792.2003 [Abstract] [Full Text] [PDF]  

Chandrani Sarkar, Debanjan Chakroborty, Rita Basu Mitra, Samir Banerjee, Partha Sarathi Dasgupta, and Sujit Basu
Dopamine in vivo inhibits VEGF-induced phosphorylation of VEGFR-2, MAPK, and focal adhesion kinase in endothelial cells
Am J Physiol Heart Circ Physiol 287: H1554-H1560, 2004; doi:10.1152/ajpheart.00272.2004 [Abstract] [Full Text] [PDF]  

E.A.V. Jones, M.H. Baron, S.E. Fraser, and M.E. Dickinson
Measuring hemodynamic changes during mammalian development
Am J Physiol Heart Circ Physiol 287: H1561-H1569, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00081.2004 [Abstract] [Full Text] [PDF]  

Aleksandre Sambelashvili and Igor R. Efimov
Dynamics of virtual electrode-induced scroll-wave reentry in a 3D bidomain model
Am J Physiol Heart Circ Physiol 287: H1570-H1581, 2004; doi:10.1152/ajpheart.01108.2003 [Abstract] [Full Text] [PDF]  

Wang Wang, Wei Sun, and Xian Wang
Intramuscular gene transfer of CGRP inhibits neointimal hyperplasia after balloon injury in the rat abdominal aorta
Am J Physiol Heart Circ Physiol 287: H1582-H1589, 2004; doi:10.1152/ajpheart.00168.2004 [Abstract] [Full Text] [PDF]  

Haruo Aramoto, Jerome W. Breslin, Peter J. Pappas, Robert W. Hobson, II, and Walter N. Durán
Vascular endothelial growth factor stimulates differential signaling pathways in in vivo microcirculation
Am J Physiol Heart Circ Physiol 287: H1590-H1598, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00767.2003 [Abstract] [Full Text] [PDF]  

M. Horackova, R. Arora, R. Chen, J. A. Armour, P. A. Cattini, R. Livingston, and Z. Byczko
Cell transplantation for treatment of acute myocardial infarction: unique capacity for repair by skeletal muscle satellite cells
Am J Physiol Heart Circ Physiol 287: H1599-H1608, 2004. First published May 27, 2004; doi:10.1152/ajpheart.00965.2003 [Abstract] [Full Text] [PDF]  

Pedro Cabrales, Nirmala Devi Kanika, Belur N. Manjula, Amy G. Tsai, Seetharama A. Acharya, and Marcos Intaglietta
Microvascular PO2 during extreme hemodilution with hemoglobin site specifically PEGylated at Cys-93({beta}) in hamster window chamber
Am J Physiol Heart Circ Physiol 287: H1609-H1617, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00146.2004 [Abstract] [Full Text] [PDF]  

Ben J. A. Janssen, Tijl De Celle, Jacques J. M. Debets, Agnieszka E. Brouns, Michael F. Callahan, and Thomas L. Smith
Effects of anesthetics on systemic hemodynamics in mice
Am J Physiol Heart Circ Physiol 287: H1618-H1624, 2004. First published May 20, 2004; doi:10.1152/ajpheart.01192.2003 [Abstract] [Full Text] [PDF]  

Katherine L. Tran, Xiangru Lu, Ming Lei, Qingping Feng, and Qingyu Wu
Upregulation of corin gene expression in hypertrophic cardiomyocytes and failing myocardium
Am J Physiol Heart Circ Physiol 287: H1625-H1631, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00298.2004 [Abstract] [Full Text] [PDF]  

Soren Schenk, Zoran B. Popovic, Yoshie Ochiai, Fernando Casas, Patrick M. McCarthy, Randall C. Starling, Michael W. Kopcak, Jr., Raymond Dessoffy, Jose L. Navia, Neil L. Greenberg, James D. Thomas, and Kiyotaka Fukamachi
Preload-adjusted right ventricular maximal power: concept and validation
Am J Physiol Heart Circ Physiol 287: H1632-H1640, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00123.2004 [Abstract] [Full Text] [PDF]  

Marie-Anne Comet, Caroline Sévoz-Couche, Naïma Hanoun, Michel Hamon, and Raul Laguzzi
5-HT-mediated inhibition of cardiovagal baroreceptor reflex response during defense reaction in the rat
Am J Physiol Heart Circ Physiol 287: H1641-H1649, 2004. First published May 27, 2004; doi:10.1152/ajpheart.01204.2003 [Abstract] [Full Text] [PDF]  

Andrew W. Bowman, Paul A. Frihauf, and Sándor J. Kovács
Time-varying effective mitral valve area: prediction and validation using cardiac MRI and Doppler echocardiography in normal subjects
Am J Physiol Heart Circ Physiol 287: H1650-H1657, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00269.2004 [Abstract] [Full Text] [PDF] [Supplemental Movies]  

N. Charkoudian, E. A. Martin, F. A. Dinenno, J. H. Eisenach, N. M. Dietz, and M. J. Joyner
Influence of increased central venous pressure on baroreflex control of sympathetic activity in humans
Am J Physiol Heart Circ Physiol 287: H1658-H1662, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00265.2004 [Abstract] [Full Text] [PDF]  

Xiao Lu, Aditya Pandit, and Ghassan S. Kassab
Biaxial incremental homeostatic elastic moduli of coronary artery: two-layer model
Am J Physiol Heart Circ Physiol 287: H1663-H1669, 2004; doi:10.1152/ajpheart.00226.2004 [Abstract] [Full Text] [PDF]  

F. P. Glor, B. Ariff, A. D. Hughes, P. R. Verdonck, D. C. Barratt, A. D. Augst, S. A. M. Thom, and X. Yun Xu
Influence of head position on carotid hemodynamics in young adults
Am J Physiol Heart Circ Physiol 287: H1670-H1681, 2004; doi:10.1152/ajpheart.01186.2003 [Abstract] [Full Text] [PDF]  

Jong-Kyung Kim, Robert A. Augustyniak, Javier A. Sala-Mercado, Robert L. Hammond, Eric J. Ansorge, Noreen F. Rossi, and Donal S. O’Leary
Heart failure alters the strength and mechanisms of arterial baroreflex pressor responses during dynamic exercise
Am J Physiol Heart Circ Physiol 287: H1682-H1688, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00358.2004 [Abstract] [Full Text] [PDF]  

Damian M. Bailey, Ian S. Young, Jane McEneny, Lesley Lawrenson, Jeannie Kim, Jeremy Barden, and Russell S. Richardson
Regulation of free radical outflow from an isolated muscle bed in exercising humans
Am J Physiol Heart Circ Physiol 287: H1689-H1699, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00148.2004 [Abstract] [Full Text] [PDF]  

Douglas R. Hamilton, Rozsa Sas, and John V. Tyberg
Atrioventricular nonuniformity of pericardial constraint
Am J Physiol Heart Circ Physiol 287: H1700-H1704, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00117.2004 [Abstract] [Full Text] [PDF]  

Guo-Chang Fan, Kimberly N. Gregory, Wen Zhao, Woo Jin Park, and Evangelia G. Kranias
Regulation of myocardial function by histidine-rich, calcium-binding protein
Am J Physiol Heart Circ Physiol 287: H1705-H1711, 2004. First published June 10, 2004; doi:10.1152/ajpheart.01211.2003 [Abstract] [Full Text] [PDF]  

Yuehua Li, Tuanzhu Ha, Xiang Gao, Jim Kelley, David L. Williams, I. William Browder, Race L. Kao, and Chuanfu Li
NF-{kappa}B activation is required for the development of cardiac hypertrophy in vivo
Am J Physiol Heart Circ Physiol 287: H1712-H1720, 2004. First published May 13, 2004; doi:10.1152/ajpheart.00124.2004 [Abstract] [Full Text] [PDF]  

Koji Miyazaki, Satoshi Komatsu, Mitsuo Ikebe, Richard A. Fenton, and James G. Dobson, Jr.
Protein kinase C{epsilon} and the antiadrenergic action of adenosine in rat ventricular myocytes
Am J Physiol Heart Circ Physiol 287: H1721-H1729, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00224.2004 [Abstract] [Full Text] [PDF]  

Ron Zohar, Baoqian Zhu, Peter Liu, Jaro Sodek, and C. A. McCulloch
Increased cell death in osteopontin-deficient cardiac fibroblasts occurs by a caspase-3-independent pathway
Am J Physiol Heart Circ Physiol 287: H1730-H1739, 2004. First published May 27, 2004; doi:10.1152/ajpheart.00098.2004 [Abstract] [Full Text] [PDF]  

Boaz D. Rosen, Bernhard L. Gerber, Thor Edvardsen, Ernesto Castillo, Luciano C. Amado, Khurram Nasir, Dara L. Kraitchman, Nael F. Osman, David A. Bluemke, and João A. C. Lima
Late systolic onset of regional LV relaxation demonstrated in three-dimensional space by MRI tissue tagging
Am J Physiol Heart Circ Physiol 287: H1740-H1746, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00080.2004 [Abstract] [Full Text] [PDF] [Supplemental Videos]  

Gary J. Grover, Karnail S. Atwal, Paul G. Sleph, Feng-Li Wang, Hossain Monshizadegan, Thomas Monticello, and David W. Green
Excessive ATP hydrolysis in ischemic myocardium by mitochondrial F1F0-ATPase: effect of selective pharmacological inhibition of mitochondrial ATPase hydrolase activity
Am J Physiol Heart Circ Physiol 287: H1747-H1755, 2004; doi:10.1152/ajpheart.01019.2003 [Abstract] [Full Text] [PDF]  

Julian E. Stelzer, Jitandrakumar R. Patel, M. Charlotte Olsson, Daniel P. Fitzsimons, Leslie A. Leinwand, and Richard L. Moss
Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium
Am J Physiol Heart Circ Physiol 287: H1756-H1761, 2004. First published May 27, 2004; doi:10.1152/ajpheart.00172.2004 [Abstract] [Full Text] [PDF]  

Steven Poelzing and David S. Rosenbaum
Altered connexin43 expression produces arrhythmia substrate in heart failure
Am J Physiol Heart Circ Physiol 287: H1762-H1770, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00346.2004 [Abstract] [Full Text] [PDF]  

Linda C. Baker, Robert Wolk, Bum-Rak Choi, Simon Watkins, Patricia Plan, Anisha Shah, and Guy Salama
Effects of mechanical uncouplers, diacetyl monoxime, and cytochalasin-D on the electrophysiology of perfused mouse hearts
Am J Physiol Heart Circ Physiol 287: H1771-H1779, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00234.2004 [Abstract] [Full Text] [PDF]  

Steve Bibevski and Mark E. Dunlap
Prevention of diminished parasympathetic control of the heart in experimental heart failure
Am J Physiol Heart Circ Physiol 287: H1780-H1785, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00430.2004 [Abstract] [Full Text] [PDF]  

Shinji Okubo, Yujirou Tanabe, Kenji Takeda, Michihiko Kitayama, Seiyu Kanemitsu, Rakesh C. Kukreja, and Noboru Takekoshi
Ischemic preconditioning and morphine attenuate myocardial apoptosis and infarction after ischemia-reperfusion in rabbits: role of {delta}-opioid receptor
Am J Physiol Heart Circ Physiol 287: H1786-H1791, 2004. First published July 1, 2004; doi:10.1152/ajpheart.01143.2003 [Abstract] [Full Text] [PDF]  

B. Friesenecker, A. G. Tsai, M. W. Dünser, A. J. Mayr, J. Martini, H. Knotzer, W. Hasibeder, and M. Intaglietta
Oxygen distribution in microcirculation after arginine vasopressin-induced arteriolar vasoconstriction
Am J Physiol Heart Circ Physiol 287: H1792-H1800, 2004. First published June 10, 2004; doi:10.1152/ajpheart.00283.2004 [Abstract] [Full Text] [PDF]  

Kelly R. Pitts and Christopher F. Toombs
Coverslip hypoxia: a novel method for studying cardiac myocyte hypoxia and ischemia in vitro
Am J Physiol Heart Circ Physiol 287: H1801-H1812, 2004. First published May 20, 2004; doi:10.1152/ajpheart.00232.2004 [Abstract] [Full Text] [PDF]  

Gordon W. Moe, Jose Marin-Garcia, Andrea Konig, Michael Goldenthal, Xiangru Lu, and Qingping Feng
In vivo TNF-{alpha} inhibition ameliorates cardiac mitochondrial dysfunction, oxidative stress, and apoptosis in experimental heart failure
Am J Physiol Heart Circ Physiol 287: H1813-H1820, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00036.2004 [Abstract] [Full Text] [PDF]  

Yoshitaka Oda, Hidetsugu Asanoi, Hiroshi Ueno, Kunihiro Yamada, Shuji Joho, Tomoki Kameyama, Tadakazu Hirai, Takashi Nozawa, Shutaro Takashima, and Hiroshi Inoue
Pulse-synchronous sympathetic burst power as a new index of sympathoexcitation in patients with heart failure
Am J Physiol Heart Circ Physiol 287: H1821-H1827, 2004. First published June 3, 2004; doi:10.1152/ajpheart.00252.2003 [Abstract] [Full Text] [PDF]  

Guo-Qing Zhu, Lie Gao, Yifan Li, Kaushik P. Patel, Irving H. Zucker, and Wei Wang
AT1 receptor mRNA antisense normalizes enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure
Am J Physiol Heart Circ Physiol 287: H1828-H1835, 2004; doi:10.1152/ajpheart.01245.2003 [Abstract] [Full Text] [PDF]  

C. Carlhäll, L. Wigström, E. Heiberg, M. Karlsson, A. F. Bolger, and E. Nylander
Contribution of mitral annular excursion and shape dynamics to total left ventricular volume change
Am J Physiol Heart Circ Physiol 287: H1836-H1841, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00103.2004 [Abstract] [Full Text] [PDF]  

Lacy L. Kolo, Thomas C. Westfall, and Heather Macarthur
Modulation of neurotransmitter release by NO is altered in mesenteric arterial bed of spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol 287: H1842-H1847, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00013.2004 [Abstract] [Full Text] [PDF]  

Karine Auger, Annie Beauséjour, Michèle Brochu, and Jean St-Louis
Increased Na+ intake during gestation in rats is associated with enhanced vascular reactivity and alterations of K+ and Ca2+ function
Am J Physiol Heart Circ Physiol 287: H1848-H1856, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00055.2004 [Abstract] [Full Text] [PDF]  

Michael Weiss, Myoungki Baek, and Wonku Kang
Systems analysis of digoxin kinetics and inotropic response in the rat heart: effects of calcium and KB-R7943
Am J Physiol Heart Circ Physiol 287: H1857-H1867, 2004. First published May 6, 2004; doi:10.1152/ajpheart.01121.2003 [Abstract] [Full Text] [PDF]  

Youping Wang and Donna H. Wang
Prevention of endothelin-1-induced increases in blood pressure: role of endogenous CGRP
Am J Physiol Heart Circ Physiol 287: H1868-H1874, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00241.2004 [Abstract] [Full Text] [PDF]  

Felice D'Agnillo
Redox active hemoglobin enhances lipopolysaccharide-induced injury to cultured bovine endothelial cells
Am J Physiol Heart Circ Physiol 287: H1875-H1882, 2004. First published June 17, 2004; doi:10.1152/ajpheart.00164.2004 [Abstract] [Full Text] [PDF]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.


Cover Caption:

Cover

Cover: Confocal microscopic image of androgenic receptors and estrogenic receptors-&agr; expression in male and female rat coronary microvascular endothelial cells. Intense immunocytochemical reactivity of estrogenic receptor-&agr; (green, FITC) is located at the cell periphery and cytoplasm. Androgenic receptor immunoreactivity (red, rhodamine) is also observed but only at the cytoplasm level. The coexpression of estrogenic receptor-&agr; and androgenic receptors (yellow) is observed only at the cytoplasm compartment. From Sierra-Ramírez A, Morato T, Campos R, Rubio I, Calzada C, Méndez E, and Ceballos G. “Acute effects of testosterone on intracellular Ca2+ kinetics in rat coronary endothelial cells are exerted via aromatization to estrogens”. Am J Physiol Heart Circ Physiol 287: H63–H71, 2004.



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