CALL FOR PAPERS:

George Cooper, IV

Cytoskeletal networks and the regulation of cardiac contractility: microtubules, hypertrophy, and cardiac dysfunction
Am J Physiol Heart Circ Physiol 291: H1003-H1014, 2006. First published May 5, 2006; doi:10.1152/ajpheart.00132.2006 [Abstract] [Full Text] [PDF]  

INVITED REVIEW:

Michel Félétou and Paul M. Vanhoutte

Endothelial dysfunction: a multifaceted disorder (The Wiggers Award Lecture)
Am J Physiol Heart Circ Physiol 291: H985-H1002, 2006. First published April 21, 2006; doi:10.1152/ajpheart.00292.2006 [Abstract] [Full Text] [PDF]  

Troy A. Baudino, Wayne Carver, Wayne Giles, and Thomas K. Borg

Cardiac fibroblasts: friend or foe?
Am J Physiol Heart Circ Physiol 291: H1015-H1026, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00023.2006 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Joël de Leiris, Michel de Lorgeril, and François Boucher

Editorial Focus  Ethanol and cardiac function
Am J Physiol Heart Circ Physiol 291: H1027-H1028, 2006; doi:10.1152/ajpheart.00480.2006 [Full Text] [PDF]  

Sarah Y. Yuan

Editorial Focus  New insights into eNOS signaling in microvascular permeability
Am J Physiol Heart Circ Physiol 291: H1029-H1031, 2006. First published May 26, 2006; doi:10.1152/ajpheart.00509.2006 [Full Text] [PDF]  

Michael J. Joyner

Editorial Focus  Exercise hyperemia: waiting for the reductionists?
Am J Physiol Heart Circ Physiol 291: H1032-H1033, 2006. First published May 26, 2006; doi:10.1152/ajpheart.00481.2006 [Full Text] [PDF]  

Paul A. Rogers, Takahiko Kiyooka, and William M. Chilian

Editorial Focus  Is there a need for another model on the pulsatile nature of coronary blood flow?
Am J Physiol Heart Circ Physiol 291: H1034-H1035, 2006. First published June 23, 2006; doi:10.1152/ajpheart.00531.2006 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Lufang Zhou, Marco E. Cabrera, Isidore C. Okere, Naveen Sharma, and William C. Stanley

Regulation of myocardial substrate metabolism during increased energy expenditure: insights from computational studies
Am J Physiol Heart Circ Physiol 291: H1036-H1046, 2006. First published April 7, 2006; doi:10.1152/ajpheart.01382.2005 [Abstract] [Full Text] [PDF]  

ARTICLES:

Gary L. Aistrup, James E. Kelly, Mariann R. Piano, and J. Andrew Wasserstrom

Biphasic changes in cardiac excitation-contraction coupling early in chronic alcohol exposure
Am J Physiol Heart Circ Physiol 291: H1047-H1057, 2006. First published April 28, 2006; doi:10.1152/ajpheart.00214.2006 [Abstract] [Full Text] [PDF]  

Fabiola A. Sánchez, Nirav B. Savalia, Ricardo G. Durán, Brajesh K. Lal, Mauricio P. Boric, and Walter N. Durán

Functional significance of differential eNOS translocation
Am J Physiol Heart Circ Physiol 291: H1058-H1064, 2006. First published May 5, 2006; doi:10.1152/ajpheart.00370.2006 [Abstract] [Full Text] [PDF]  

Anna M. Rogers, Natasha R. Saunders, Kyra E. Pyke, and Michael E. Tschakovsky

Rapid vasoregulatory mechanisms in exercising human skeletal muscle: dynamic response to repeated changes in contraction intensity
Am J Physiol Heart Circ Physiol 291: H1065-H1073, 2006. First published May 5, 2006; doi:10.1152/ajpheart.00368.2006 [Abstract] [Full Text] [PDF]  

Yunlong Huo and Ghassan S. Kassab

Pulsatile blood flow in the entire coronary arterial tree: theory and experiment
Am J Physiol Heart Circ Physiol 291: H1074-H1087, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00200.2006 [Abstract] [Full Text] [PDF]  

K. H. W. J. ten Tusscher and A. V. Panfilov

Alternans and spiral breakup in a human ventricular tissue model
Am J Physiol Heart Circ Physiol 291: H1088-H1100, 2006. First published March 24, 2006; doi:10.1152/ajpheart.00109.2006 [Abstract] [Full Text] [PDF]  

Tepmanas Bupha-Intr and Jonggonnee Wattanapermpool

Regulatory role of ovarian sex hormones in calcium uptake activity of cardiac sarcoplasmic reticulum
Am J Physiol Heart Circ Physiol 291: H1101-H1108, 2006. First published March 3, 2006; doi:10.1152/ajpheart.00660.2005 [Abstract] [Full Text] [PDF]  

Bing S. Huang, Warren J. Cheung, Hao Wang, Junhui Tan, Roselyn A. White, and Frans H. H. Leenen

Activation of brain renin-angiotensin-aldosterone system by central sodium in Wistar rats
Am J Physiol Heart Circ Physiol 291: H1109-H1117, 2006. First published April 7, 2006; doi:10.1152/ajpheart.00024.2006 [Abstract] [Full Text] [PDF]  

Anlong Li, Adebowale Adebiyi, Charles W. Leffler, and Jonathan H. Jaggar

K_Ca channel insensitivity to Ca²⁺ sparks underlies fractional uncoupling in newborn cerebral artery smooth muscle cells
Am J Physiol Heart Circ Physiol 291: H1118-H1125, 2006. First published April 7, 2006; doi:10.1152/ajpheart.01308.2005 [Abstract] [Full Text] [PDF]  

Isaac George, Geng-Hua Yi, Allison R. Schulman, Brad T. Morrow, Yanping Cheng, Anguo Gu, Geping Zhang, Mehmet C. Oz, Daniel Burkhoff, and Jie Wang

A polymerized bovine hemoglobin oxygen carrier preserves regional myocardial function and reduces infarct size after acute myocardial ischemia
Am J Physiol Heart Circ Physiol 291: H1126-H1137, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00076.2006 [Abstract] [Full Text] [PDF]  

Toyotaka Yada, Hiroaki Shimokawa, Osamu Hiramatsu, Yoshisuke Haruna, Yoshitaka Morita, Naoki Kashihara, Yoshiro Shinozaki, Hidezo Mori, Masami Goto, Yasuo Ogasawara, and Fumihiko Kajiya

Cardioprotective role of endogenous hydrogen peroxide during ischemia-reperfusion injury in canine coronary microcirculation in vivo
Am J Physiol Heart Circ Physiol 291: H1138-H1146, 2006. First published April 28, 2006; doi:10.1152/ajpheart.00187.2006 [Abstract] [Full Text] [PDF]  

J. D. Rojas, S. R. Sennoune, D. Maiti, K. Bakunts, M. Reuveni, S. C. Sanka, G. M. Martinez, E. A. Seftor, C. J. Meininger, G. Wu, D. E. Wesson, M. J. C. Hendrix, and R. Martínez-Zaguilán

Vacuolar-type H⁺-ATPases at the plasma membrane regulate pH and cell migration in microvascular endothelial cells
Am J Physiol Heart Circ Physiol 291: H1147-H1157, 2006. First published May 5, 2006; doi:10.1152/ajpheart.00166.2006 [Abstract] [Full Text] [PDF]  

Yumei Ye, Yu Lin, Shaul Atar, Ming-He Huang, Jose R. Perez-Polo, Barry F. Uretsky, and Yochai Birnbaum

Myocardial protection by pioglitazone, atorvastatin, and their combination: mechanisms and possible interactions
Am J Physiol Heart Circ Physiol 291: H1158-H1169, 2006. First published April 7, 2006; doi:10.1152/ajpheart.00096.2006 [Abstract] [Full Text] [PDF]  

Sridevi Devaraj, Benjamin Davis, Scott I. Simon, and Ishwarlal Jialal

CRP promotes monocyte-endothelial cell adhesion via Fc receptors in human aortic endothelial cells under static and shear flow conditions
Am J Physiol Heart Circ Physiol 291: H1170-H1176, 2006. First published April 7, 2006; doi:10.1152/ajpheart.00150.2006 [Abstract] [Full Text] [PDF]  

Arnaud Mansart, Pierre-Edouard Bollaert, Philippe Giummelly, Christine Capdeville-Atkinson, and Jeffrey Atkinson

Effects of dexamethasone and L-canavanine on the intracellular calcium-contraction relation of the rat tail artery during septic shock
Am J Physiol Heart Circ Physiol 291: H1177-H1182, 2006. First published April 7, 2006; doi:10.1152/ajpheart.00997.2005 [Abstract] [Full Text] [PDF]  

Nicole D. Glaser, Yevgeniya O. Lukyanenko, Yibin Wang, Gerald M. Wilson, and Terry B. Rogers

JNK activation decreases PP2A regulatory subunit B56 expression and mRNA stability and increases AUF1 expression in cardiomyocytes
Am J Physiol Heart Circ Physiol 291: H1183-H1192, 2006. First published April 7, 2006; doi:10.1152/ajpheart.01162.2005 [Abstract] [Full Text] [PDF]  

Daniel J. Green, Andrew J. Maiorana, Michael E. Tschakovsky, Kyra E. Pyke, Cara J. Weisbrod, and Gerry O’Driscoll

Relationship between changes in brachial artery flow-mediated dilation and basal release of nitric oxide in subjects with Type 2 diabetes
Am J Physiol Heart Circ Physiol 291: H1193-H1199, 2006. First published March 24, 2006; doi:10.1152/ajpheart.01176.2005 [Abstract] [Full Text] [PDF]  

Chong Wang, Marisa Garcia, Xiao Lu, Yoram Lanir, and Ghassan S. Kassab

Three-dimensional mechanical properties of porcine coronary arteries: a validated two-layer model
Am J Physiol Heart Circ Physiol 291: H1200-H1209, 2006. First published March 31, 2006; doi:10.1152/ajpheart.01323.2005 [Abstract] [Full Text] [PDF]  

Matt M. Riordan and Sándor J. Kovács

Relationship of pulmonary vein flow to left ventricular short-axis epicardial displacement in diastole: model-based prediction with in vivo validation
Am J Physiol Heart Circ Physiol 291: H1210-H1215, 2006. First published April 7, 2006; doi:10.1152/ajpheart.01339.2005 [Abstract] [Full Text] [PDF]  

Willie D. Zoma, R. Scott Baker, John L. Mershon, and Kenneth E. Clark

Hemodynamic effects of acute and repeated exposure to raloxifene in ovariectomized sheep
Am J Physiol Heart Circ Physiol 291: H1216-H1225, 2006. First published March 3, 2006; doi:10.1152/ajpheart.00666.2005 [Abstract] [Full Text] [PDF]  

Hui Dong, Yanfen Jiang, Chris R. Triggle, Xiaofang Li, and Jonathan Lytton

Novel role for K⁺-dependent Na⁺/Ca²⁺ exchangers in regulation of cytoplasmic free Ca²⁺ and contractility in arterial smooth muscle
Am J Physiol Heart Circ Physiol 291: H1226-H1235, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00196.2006 [Abstract] [Full Text] [PDF]  

Oana Sorop, Erik N. T. P. Bakker, Adrian Pistea, Jos A. E. Spaan, and Ed VanBavel

Calcium channel blockade prevents pressure-dependent inward remodeling in isolated subendocardial resistance vessels
Am J Physiol Heart Circ Physiol 291: H1236-H1245, 2006. First published March 24, 2006; doi:10.1152/ajpheart.00838.2005 [Abstract] [Full Text] [PDF]  

Andrea L. Fellet, Ana M. Balaszczuk, Cristina Arranz, Juan José López-Costa, Alberto Boveris, and Juanita Bustamante

Autonomic regulation of pacemaker activity: role of heart nitric oxide synthases
Am J Physiol Heart Circ Physiol 291: H1246-H1254, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00711.2005 [Abstract] [Full Text] [PDF]  

Zhaohui Gao, Valerie Kehoe, Jihong Xing, Lawrence Sinoway, and Jianhua Li

Temperature modulates P2X receptor-mediated cardiovascular responses to muscle afferent activation
Am J Physiol Heart Circ Physiol 291: H1255-H1261, 2006. First published February 24, 2006; doi:10.1152/ajpheart.01303.2005 [Abstract] [Full Text] [PDF]  

Sheng Li, Hideyuki Tanaka, Hong Hui Wang, Shinji Yoshiyama, Hiroyuki Kumagai, Akio Nakamura, Dawn L. Brown, Sean E. Thatcher, Gary L. Wright, and Kazuhiro Kohama

Intracellular signal transduction for migration and actin remodeling in vascular smooth muscle cells after sphingosylphosphorylcholine stimulation
Am J Physiol Heart Circ Physiol 291: H1262-H1272, 2006; doi:10.1152/ajpheart.00901.2005 [Abstract] [Full Text] [PDF]  

Thomas L'Ecuyer, Sanjeev Sanjeev, Ronald Thomas, Raymond Novak, Lauri Das, Wendy Campbell, and Richard Vander Heide

DNA damage is an early event in doxorubicin-induced cardiac myocyte death
Am J Physiol Heart Circ Physiol 291: H1273-H1280, 2006. First published March 24, 2006; doi:10.1152/ajpheart.00738.2005 [Abstract] [Full Text] [PDF]  

Tsung-Ming Lee, Mei-Shu Lin, Tsai-Fwu Chou, and Nen-Chung Chang

Additive effects of combined blockade of AT₁ receptor and HMG-CoA reductase on left ventricular remodeling in infarcted rats
Am J Physiol Heart Circ Physiol 291: H1281-H1289, 2006. First published March 24, 2006; doi:10.1152/ajpheart.00792.2005 [Abstract] [Full Text] [PDF]  

Motoyuki Iemitsu, Seiji Maeda, Subrina Jesmin, Takeshi Otsuki, and Takashi Miyauchi

Exercise training improves aging-induced downregulation of VEGF angiogenic signaling cascade in hearts
Am J Physiol Heart Circ Physiol 291: H1290-H1298, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00820.2005 [Abstract] [Full Text] [PDF]  

Carmen C. Sucharov, Peter D. Mariner, Karin R. Nunley, Carlin Long, Leslie Leinwand, and Michael R. Bristow

A ₁-adrenergic receptor CaM kinase II-dependent pathway mediates cardiac myocyte fetal gene induction
Am J Physiol Heart Circ Physiol 291: H1299-H1308, 2006. First published February 24, 2006; doi:10.1152/ajpheart.00017.2006 [Abstract] [Full Text] [PDF]  

Wei Zhou, Liang-Wu Fu, Stephanie C. Tjen-A-Looi, Zhi-ling Guo, and John C. Longhurst

Role of glutamate in a visceral sympathoexcitatory reflex in rostral ventrolateral medulla of cats
Am J Physiol Heart Circ Physiol 291: H1309-H1318, 2006. First published April 21, 2006; doi:10.1152/ajpheart.00202.2006 [Abstract] [Full Text] [PDF]  

Micaela C. Jantzi, Suzanne E. Brett, William F. Jackson, Randolph Corteling, Edward J. Vigmond, and Donald G. Welsh

Inward rectifying potassium channels facilitate cell-to-cell communication in hamster retractor muscle feed arteries
Am J Physiol Heart Circ Physiol 291: H1319-H1328, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00217.2006 [Abstract] [Full Text] [PDF]  

Istvan Bak, Istvan Lekli, Bela Juhasz, Norbert Nagy, Edit Varga, Judit Varadi, Rudolf Gesztelyi, Gergo Szabo, Levente Szendrei, Ildiko Bacskay, Miklos Vecsernyes, Miklos Antal, Laszlo Fesus, Francois Boucher, Joel de Leiris, and Arpad Tosaki

Cardioprotective mechanisms of Prunus cerasus (sour cherry) seed extract against ischemia-reperfusion-induced damage in isolated rat hearts
Am J Physiol Heart Circ Physiol 291: H1329-H1336, 2006. First published April 14, 2006; doi:10.1152/ajpheart.01243.2005 [Abstract] [Full Text] [PDF]  

Shunichi Kawano, Toru Kubota, Yoshiya Monden, Takaki Tsutsumi, Takahiro Inoue, Natsumi Kawamura, Hiroyuki Tsutsui, and Kenji Sunagawa

Blockade of NF-B improves cardiac function and survival after myocardial infarction
Am J Physiol Heart Circ Physiol 291: H1337-H1344, 2006. First published April 21, 2006; doi:10.1152/ajpheart.01175.2005 [Abstract] [Full Text] [PDF]  

Nicolas Couvreur, Laurence Lucats, Renaud Tissier, Alain Bize, Alain Berdeaux, and Bijan Ghaleh

Differential effects of postconditioning on myocardial stunning and infarction: a study in conscious dogs and anesthetized rabbits
Am J Physiol Heart Circ Physiol 291: H1345-H1350, 2006. First published March 24, 2006; doi:10.1152/ajpheart.00124.2006 [Abstract] [Full Text] [PDF]  

Sa'ed Akkawi, Taher Nassar, Mark Tarshis, Douglas B. Cines, and Abd Al-Roof Higazi

LRP and _v3 mediate tPA activation of smooth muscle cells
Am J Physiol Heart Circ Physiol 291: H1351-H1359, 2006. First published February 17, 2006; doi:10.1152/ajpheart.01042.2005 [Abstract] [Full Text] [PDF]  

Heidi Vierimaa, Jarkko Ronkainen, Heikki Ruskoaho, and Olli Vuolteenaho

Synergistic activation of salmon cardiac function by endothelin and -adrenergic stimulation
Am J Physiol Heart Circ Physiol 291: H1360-H1370, 2006. First published March 24, 2006; doi:10.1152/ajpheart.01326.2005 [Abstract] [Full Text] [PDF]  

Bert-Inge Rosengren, Anna Rippe, Catarina Rippe, Daniele Venturoli, Karl Swärd, and Bengt Rippe

Transvascular protein transport in mice lacking endothelial caveolae
Am J Physiol Heart Circ Physiol 291: H1371-H1377, 2006. First published February 24, 2006; doi:10.1152/ajpheart.01364.2005 [Abstract] [Full Text] [PDF]  

N. Charkoudian, M. J. Joyner, S. A. Barnes, C. P. Johnson, J. H. Eisenach, N. M. Dietz, and B. G. Wallin

Relationship between muscle sympathetic nerve activity and systemic hemodynamics during nitric oxide synthase inhibition in humans
Am J Physiol Heart Circ Physiol 291: H1378-H1383, 2006. First published April 28, 2006; doi:10.1152/ajpheart.00234.2006 [Abstract] [Full Text] [PDF]  

Mao Jiang, Ande Xu, and Njanoor Narayanan

Thyroid hormone downregulates the expression and function of sarcoplasmic reticulum-associated CaM kinase II in the rabbit heart
Am J Physiol Heart Circ Physiol 291: H1384-H1394, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00875.2005 [Abstract] [Full Text] [PDF]  

Francisco R. González-Pacheco, Juan J. P. Deudero, María C. Castellanos, María Angeles Castilla, María Victoria Álvarez-Arroyo, Susana Yagüe, and Carlos Caramelo

Mechanisms of endothelial response to oxidative aggression: protective role of autologous VEGF and induction of VEGFR2 by H₂O₂
Am J Physiol Heart Circ Physiol 291: H1395-H1401, 2006; doi:10.1152/ajpheart.01277.2005 [Abstract] [Full Text] [PDF]  

Joseph M. Rutkowski, Kendrick C. Boardman, and Melody A. Swartz

Characterization of lymphangiogenesis in a model of adult skin regeneration
Am J Physiol Heart Circ Physiol 291: H1402-H1410, 2006. First published April 28, 2006; doi:10.1152/ajpheart.00038.2006 [Abstract] [Full Text] [PDF]  

Asim Azfer, Jianli Niu, Linda M. Rogers, Frances M. Adamski, and Pappachan E. Kolattukudy

Activation of endoplasmic reticulum stress response during the development of ischemic heart disease
Am J Physiol Heart Circ Physiol 291: H1411-H1420, 2006. First published April 14, 2006; doi:10.1152/ajpheart.01378.2005 [Abstract] [Full Text] [PDF]  

Junwu Mu and S. Lee Adamson

Developmental changes in hemodynamics of uterine artery, utero- and umbilicoplacental, and vitelline circulations in mouse throughout gestation
Am J Physiol Heart Circ Physiol 291: H1421-H1428, 2006. First published April 7, 2006; doi:10.1152/ajpheart.00031.2006 [Abstract] [Full Text] [PDF] [Supplemental Video]  

Dong Sun, Hong Liu, Changdong Yan, Azita Jacobson, Caroline Ojaimi, An Huang, and Gabor Kaley

COX-2 contributes to the maintenance of flow-induced dilation in arterioles of eNOS-knockout mice
Am J Physiol Heart Circ Physiol 291: H1429-H1435, 2006. First published April 21, 2006; doi:10.1152/ajpheart.01130.2005 [Abstract] [Full Text] [PDF]  

Paavo Korge and James N. Weiss

Redox regulation of endogenous substrate oxidation by cardiac mitochondria
Am J Physiol Heart Circ Physiol 291: H1436-H1445, 2006. First published April 14, 2006; doi:10.1152/ajpheart.01292.2005 [Abstract] [Full Text] [PDF]  

Yiqiang Zhang, Jiening Xiao, Huizhen Wang, Xiaobin Luo, Jingxiong Wang, Louis R. Villeneuve, Haiqing Zhang, Yunlong Bai, Baofeng Yang, and Zhiguo Wang

Restoring depressed HERG K⁺ channel function as a mechanism for insulin treatment of abnormal QT prolongation and associated arrhythmias in diabetic rabbits
Am J Physiol Heart Circ Physiol 291: H1446-H1455, 2006. First published April 14, 2006; doi:10.1152/ajpheart.01356.2005 [Abstract] [Full Text] [PDF]  

Edwin A. Deitch, Preya Ananthakrishnan, David B. Cohen, Da Zhong Xu, Eleonora Feketeova, and Carl J. Hauser

Neutrophil activation is modulated by sex hormones after trauma-hemorrhagic shock and burn injuries
Am J Physiol Heart Circ Physiol 291: H1456-H1465, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00694.2005 [Abstract] [Full Text] [PDF]  

Bernard Korzeniewski

Oxygen consumption and metabolite concentrations during transitions between different work intensities in heart
Am J Physiol Heart Circ Physiol 291: H1466-H1474, 2006. First published May 5, 2006; doi:10.1152/ajpheart.00004.2006 [Abstract] [Full Text] [PDF]  

INNOVATIVE METHODOLOGY:

Yuru Zhong, Kung-Ming Jan, Ki Hwan Ju, and Ki H. Chon

Quantifying cardiac sympathetic and parasympathetic nervous activities using principal dynamic modes analysis of heart rate variability
Am J Physiol Heart Circ Physiol 291: H1475-H1483, 2006. First published April 7, 2006; doi:10.1152/ajpheart.00005.2006 [Abstract] [Full Text] [PDF]  

LETTERS TO THE EDITOR:

Harold Bien, Emilia Entcheva, Arkady Pertsov, Sergey Mironov, and Frederick Vetter

Spatial Frequency Content in Optical Mapping of Cardiac Cell Monolayers
Am J Physiol Heart Circ Physiol 291: H1484-H1485, 2006. First published May 19, 2006; doi:10.1152/ajpheart.00433.2006 [Abstract] [Full Text] [PDF]  

Sean M. Davidson, Derek M. Yellon, Brajesh K. Lal, Shubha Varma, Ruifang Zheng, Peter J. Pappas, and Walter N. Durán

Does Hyperglycemia Reduce Proliferation or Increase Apoptosis?
Am J Physiol Heart Circ Physiol 291: H1486-H1487, 2006. First published April 14, 2006; doi:10.1152/ajpheart.00301.2006 [Abstract] [Full Text] [PDF]  

CORRIGENDUM:

Corrigendum
Am J Physiol Heart Circ Physiol 291: H1488-H1488, 2006; doi:10.1152/ajpheart.00692.2006 [Full Text] [PDF]  

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