AJP - Heart and Circulatory Physiology -- Table of Contents (February 1 2008, 294 [2])

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INVITED REVIEW:

Jeffrey S. Gilbert, Michael J. Ryan, Babbette B. LaMarca, Mona Sedeek, Sydney R. Murphy, and Joey P. Granger: Pathophysiology of hypertension during preeclampsia: linking placental ischemia with endothelial dysfunction
Am J Physiol Heart Circ Physiol 294: H541-H550, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01113.2007 [Abstract] [Full Text] [PDF]

Chunyu Zeng, Ines Armando, Yingjin Luo, Gilbert M. Eisner, Robin A. Felder, and Pedro A. Jose: Dysregulation of dopamine-dependent mechanisms as a determinant of hypertension: studies in dopamine receptor knockout mice
Am J Physiol Heart Circ Physiol 294: H551-H569, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01036.2007 [Abstract] [Full Text] [PDF]

Stephen L. Archer, Mardi Gomberg-Maitland, Michael L. Maitland, Stuart Rich, Joe G. N. Garcia, and E. Kenneth Weir: Mitochondrial metabolism, redox signaling, and fusion: a mitochondria-ROS-HIF-1 ${alpha}$ -Kv1.5 O₂-sensing pathway at the intersection of pulmonary hypertension and cancer
Am J Physiol Heart Circ Physiol 294: H570-H578, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01324.2007 [Abstract] [Full Text] [PDF]

EDITORIAL FOCUS:

Martin D. Bootman and H. Llewelyn Roderick: Why, where, and when do cardiac myocytes express inositol 1,4,5-trisphosphate receptors?
Am J Physiol Heart Circ Physiol 294: H579-H581, 2008. First published December 7, 2007; doi:10.1152/ajpheart.01378.2007 [Full Text] [PDF]

Arthur L. Klatsky: Alcohol, wine, and vascular diseases: an abundance of paradoxes
Am J Physiol Heart Circ Physiol 294: H582-H583, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01387.2007 [Full Text] [PDF]

Joseph Y. Cheung: Regulation of cardiac contractility: high time for FXYD
Am J Physiol Heart Circ Physiol 294: H584-H585, 2008; doi:10.1152/ajpheart.91430.2007 [Full Text] [PDF]

Juan C. Sáez: Astrocytes as connexin-dependent signaling cells for local blood flow regulation
Am J Physiol Heart Circ Physiol 294: H586-H587, 2008; doi:10.1152/ajpheart.91445.2007 [Full Text] [PDF]

Lars S. Maier: Vitamin A for the heart: progress for cardiac hypertrophy regression?
Am J Physiol Heart Circ Physiol 294: H588-H589, 2008; doi:10.1152/ajpheart.00002.2008 [Full Text] [PDF]

TRANSLATIONAL PHYSIOLOGY:

Masayuki Kubo, Tao-Sheng Li, Ryo Suzuki, Bungo Shirasawa, Noriyasu Morikage, Mako Ohshima, Shu-Lan Qin, and Kimikazu Hamano: Hypoxic preconditioning increases survival and angiogenic potency of peripheral blood mononuclear cells via oxidative stress resistance
Am J Physiol Heart Circ Physiol 294: H590-H595, 2008. First published December 21, 2007; doi:10.1152/ajpheart.00856.2007 [Abstract] [Full Text] [PDF]

ARTICLES:

Timothy L. Domeier, Aleksey V. Zima, Joshua T. Maxwell, Sabine Huke, Gregory A. Mignery, and Lothar A. Blatter: IP₃ receptor-dependent Ca²⁺ release modulates excitation-contraction coupling in rabbit ventricular myocytes
Am J Physiol Heart Circ Physiol 294: H596-H604, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01155.2007 [Abstract] [Full Text] [PDF]

Jonas Spaak, Anthony C. Merlocco, George J. Soleas, George Tomlinson, Beverley L. Morris, Peter Picton, Catherine F. Notarius, Christopher T. Chan, and John S. Floras: Dose-related effects of red wine and alcohol on hemodynamics, sympathetic nerve activity, and arterial diameter
Am J Physiol Heart Circ Physiol 294: H605-H612, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01162.2007 [Abstract] [Full Text] [PDF]

James R. Bell, Erika Kennington, William Fuller, Kushal Dighe, Pamela Donoghue, James E. Clark, Li-Guo Jia, Amy L. Tucker, J. Randall Moorman, Michael S. Marber, Philip Eaton, Michael J. Dunn, and Michael J. Shattock: Characterization of the phospholemman knockout mouse heart: depressed left ventricular function with increased Na-K-ATPase activity
Am J Physiol Heart Circ Physiol 294: H613-H621, 2008. First published December 7, 2007; doi:10.1152/ajpheart.01332.2007 [Abstract] [Full Text] [PDF]

Hao-Liang Xu, Lizhen Mao, Shuhua Ye, Chanannait Paisansathan, Francesco Vetri, and Dale A. Pelligrino: Astrocytes are a key conduit for upstream signaling of vasodilation during cerebral cortical neuronal activation in vivo
Am J Physiol Heart Circ Physiol 294: H622-H632, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00530.2007 [Abstract] [Full Text] [PDF]

Rashmi Choudhary, Ants Palm-Leis, Robert C. Scott, III, Rakeshwar S. Guleria, Eric Rachut, Kenneth M. Baker, and Jing Pan: All-trans retinoic acid prevents development of cardiac remodeling in aortic banded rats by inhibiting the renin-angiotensin system
Am J Physiol Heart Circ Physiol 294: H633-H644, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01301.2007 [Abstract] [Full Text] [PDF]

William E. Stansfield, Ru-Hang Tang, Nancy C. Moss, Albert S. Baldwin, Monte S. Willis, and Craig H. Selzman: Proteasome inhibition promotes regression of left ventricular hypertrophy
Am J Physiol Heart Circ Physiol 294: H645-H650, 2008. First published November 21, 2007; doi:10.1152/ajpheart.00196.2007 [Abstract] [Full Text] [PDF]

Meital Cohen-Mazor, Shifra Sela, Rafi Mazor, Neta Ilan, Israel Vlodavsky, Angelique L. Rops, Johan van der Vlag, Hector I. Cohen, and Batya Kristal: Are primed polymorphonuclear leukocytes contributors to the high heparanase levels in hemodialysis patients?
Am J Physiol Heart Circ Physiol 294: H651-H658, 2008. First published November 21, 2007; doi:10.1152/ajpheart.00952.2007 [Abstract] [Full Text] [PDF]

Hong D. Xiao, Sebastien Fuchs, Ellen A. Bernstein, Ping Li, Duncan J. Campbell, and Kenneth E. Bernstein: Mice expressing ACE only in the heart show that increased cardiac angiotensin II is not associated with cardiac hypertrophy
Am J Physiol Heart Circ Physiol 294: H659-H667, 2008. First published November 21, 2007; doi:10.1152/ajpheart.01147.2007 [Abstract] [Full Text] [PDF]

Victoria E. Claydon and Andrei V. Krassioukov: Clinical correlates of frequency analyses of cardiovascular control after spinal cord injury
Am J Physiol Heart Circ Physiol 294: H668-H678, 2008. First published November 16, 2007; doi:10.1152/ajpheart.00869.2007 [Abstract] [Full Text] [PDF]

Xin Tang, Nitin Aggarwal, Blythe B. Holmes, Hartmut Kuhn, and William B. Campbell: Age-related decrease in 15-lipoxygenase contributes to reduced vasorelaxation in rabbit aorta
Am J Physiol Heart Circ Physiol 294: H679-H687, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01053.2007 [Abstract] [Full Text] [PDF]

Paul A. Dabisch, John T. Liles, Syed R. Baber, Neel H. Golwala, S. N. Murthy, and Philip J. Kadowitz: Analysis of L-NAME-dependent and -resistant responses to acetylcholine in the rat
Am J Physiol Heart Circ Physiol 294: H688-H698, 2008. First published November 21, 2007; doi:10.1152/ajpheart.00394.2007 [Abstract] [Full Text] [PDF]

Ellen Steward Pentz, Maria Luisa S. Sequeira Lopez, Magali Cordaillat, and R. Ariel Gomez: Identity of the renin cell is mediated by cAMP and chromatin remodeling: an in vitro model for studying cell recruitment and plasticity
Am J Physiol Heart Circ Physiol 294: H699-H707, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01152.2007 [Abstract] [Full Text] [PDF]

Sonia Nogueras, Ana Merino, Raquel Ojeda, Julia Carracedo, Mariano Rodriguez, Alejandro Martin-Malo, Rafael Ramírez, and Pedro Aljama: Coupling of endothelial injury and repair: an analysis using an in vivo experimental model
Am J Physiol Heart Circ Physiol 294: H708-H713, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00466.2007 [Abstract] [Full Text] [PDF]

Benjamin Kaimovitz, Yunlong Huo, Yoram Lanir, and Ghassan S. Kassab: Diameter asymmetry of porcine coronary arterial trees: structural and functional implications
Am J Physiol Heart Circ Physiol 294: H714-H723, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00818.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables]

Anuradha Dhanasekaran, Stephanie K. Gruenloh, J. Noelle Buonaccorsi, Rong Zhang, Garrett J. Gross, John R. Falck, Paresh K. Patel, Elizabeth R. Jacobs, and Meetha Medhora: Multiple antiapoptotic targets of the PI3K/Akt survival pathway are activated by epoxyeicosatrienoic acids to protect cardiomyocytes from hypoxia/anoxia
Am J Physiol Heart Circ Physiol 294: H724-H735, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00979.2007 [Abstract] [Full Text] [PDF]

Lee K. Landeen, Dorothy A. Dederko, Colleen S. Kondo, Betty S. Hu, Nakon Aroonsakool, Jason H. Haga, and Wayne R. Giles: Mechanisms of the negative inotropic effects of sphingosine-1-phosphate on adult mouse ventricular myocytes
Am J Physiol Heart Circ Physiol 294: H736-H749, 2008. First published November 16, 2007; doi:10.1152/ajpheart.00316.2007 [Abstract] [Full Text] [PDF]

Tomoko Ichiki, Michihisa Jougasaki, Manabu Setoguchi, Junichi Imamura, Hitoshi Nakashima, Tatsuru Matsuoka, Masahiro Sonoda, Kazuhiko Nakamura, Shinichi Minagoe, and Chuwa Tei: Cardiotrophin-1 stimulates intercellular adhesion molecule-1 and monocyte chemoattractant protein-1 in human aortic endothelial cells
Am J Physiol Heart Circ Physiol 294: H750-H763, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00161.2007 [Abstract] [Full Text] [PDF]

R. H. Keldermann, K. H. W. J. ten Tusscher, M. P. Nash, R. Hren, P. Taggart, and A. V. Panfilov: Effect of heterogeneous APD restitution on VF organization in a model of the human ventricles
Am J Physiol Heart Circ Physiol 294: H764-H774, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00906.2007 [Abstract] [Full Text] [PDF]

Marcel Bassil, Yuan Li, and Madhu B. Anand-Srivastava: Peroxynitrite inhibits the expression of G_i ${alpha}$ protein and adenylyl cyclase signaling in vascular smooth muscle cells
Am J Physiol Heart Circ Physiol 294: H775-H784, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00841.2007 [Abstract] [Full Text] [PDF]

A. S. Laird, A. M. Finch, P. M. E. Waite, and P. Carrive: Peripheral changes above and below injury level lead to prolonged vascular responses following high spinal cord injury
Am J Physiol Heart Circ Physiol 294: H785-H792, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01002.2007 [Abstract] [Full Text] [PDF]

Kenji Tsujimae, Shingo Murakami, and Yoshihisa Kurachi: In silico study on the effects of I_Kur block kinetics on prolongation of human action potential after atrial fibrillation-induced electrical remodeling
Am J Physiol Heart Circ Physiol 294: H793-H800, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01229.2007 [Abstract] [Full Text] [PDF]

Xiaowei Sun and David D. Ku: Rosuvastatin provides pleiotropic protection against pulmonary hypertension, right ventricular hypertrophy, and coronary endothelial dysfunction in rats
Am J Physiol Heart Circ Physiol 294: H801-H809, 2008. First published November 30, 2007; doi:10.1152/ajpheart.01112.2007 [Abstract] [Full Text] [PDF]

Carly LaCroix, Jessica Freeling, Alese Giles, Jürgen Wess, and Yi-Fan Li: Deficiency of M₂ muscarinic acetylcholine receptors increases susceptibility of ventricular function to chronic adrenergic stress
Am J Physiol Heart Circ Physiol 294: H810-H820, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00724.2007 [Abstract] [Full Text] [PDF]

Nathalie Baudry, Elisabeth Laemmel, and Eric Vicaut: In vivo reactive oxygen species production induced by ischemia in muscle arterioles of mice: involvement of xanthine oxidase and mitochondria
Am J Physiol Heart Circ Physiol 294: H821-H828, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00378.2007 [Abstract] [Full Text] [PDF]

Shekhar H. Deo, Matthew A. Barlow, Leticia Gonzalez, Darice Yoshishige, and James L. Caffrey: Cholinergic location of ${delta}$ -opioid receptors in canine atria and SA node
Am J Physiol Heart Circ Physiol 294: H829-H838, 2008. First published November 21, 2007; doi:10.1152/ajpheart.01141.2007 [Abstract] [Full Text] [PDF]

Julie Basu Ray, Sara Arab, Yupu Deng, Peter Liu, Linda Penn, David W. Courtman, and Michael E. Ward: Oxygen regulation of arterial smooth muscle cell proliferation and survival
Am J Physiol Heart Circ Physiol 294: H839-H852, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00587.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]

Jasmina Varagic, Edward D. Frohlich, Dinko Susic, Jwari Ahn, Luis Matavelli, Begoña López, and Javier Díez: AT₁ receptor antagonism attenuates target organ effects of salt excess in SHRs without affecting pressure
Am J Physiol Heart Circ Physiol 294: H853-H858, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00737.2007 [Abstract] [Full Text] [PDF]

Istvan Lekli, Gergo Szabo, Bela Juhasz, Samarjit Das, Manika Das, Edit Varga, Levente Szendrei, Rudolf Gesztelyi, Judit Varadi, Istvan Bak, Dipak K. Das, and Arpad Tosaki: Protective mechanisms of resveratrol against ischemia-reperfusion-induced damage in hearts obtained from Zucker obese rats: the role of GLUT-4 and endothelin
Am J Physiol Heart Circ Physiol 294: H859-H866, 2008. First published December 7, 2007; doi:10.1152/ajpheart.01048.2007 [Abstract] [Full Text] [PDF]

Dong-Feng Yeih, Lian-Yu Lin, Hung-I Yeh, Yu-Jun Lai, Fu-Tien Chiang, Chuen-Den Tseng, Shu-Hsun Chu, and Yung-Zu Tseng: Temporal changes in cardiac force- and flow-generation capacity, loading conditions, and mechanical efficiency in streptozotocin-induced diabetic rats
Am J Physiol Heart Circ Physiol 294: H867-H874, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00573.2007 [Abstract] [Full Text] [PDF]

Anne M. Deschamps, Juozas Zavadzkas, Rebecca L. Murphy, Christine N. Koval, Julie E. McLean, Laura Jeffords, Stuart M. Saunders, Nina J. Sheats, Robert E. Stroud, and Francis G. Spinale: Interruption of endothelin signaling modifies membrane type 1 matrix metalloproteinase activity during ischemia and reperfusion
Am J Physiol Heart Circ Physiol 294: H875-H883, 2008. First published December 7, 2007; doi:10.1152/ajpheart.00918.2007 [Abstract] [Full Text] [PDF]

Leonhard Schäffer, Tilo Burkhardt, Deborah Müller-Vizentini, Manfred Rauh, Maren Tomaske, Romaine Arlettaz Mieth, Urs Bauersfeld, and Ernst Beinder: Cardiac autonomic balance in small-for-gestational-age neonates
Am J Physiol Heart Circ Physiol 294: H884-H890, 2008. First published December 7, 2007; doi:10.1152/ajpheart.00318.2007 [Abstract] [Full Text] [PDF]

Ruud D. Fontijn, Oscar L. Volger, Joost O. Fledderus, Arie Reijerkerk, Helga E. de Vries, and Anton J. G. Horrevoets: SOX-18 controls endothelial-specific claudin-5 gene expression and barrier function
Am J Physiol Heart Circ Physiol 294: H891-H900, 2008. First published December 7, 2007; doi:10.1152/ajpheart.01248.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures and Tables]

Elise Belaidi, Pauline C. Beguin, Patrick Levy, Christophe Ribuot, and Diane Godin-Ribuot: Prevention of HIF-1 activation and iNOS gene targeting by low-dose cadmium results in loss of myocardial hypoxic preconditioning in the rat
Am J Physiol Heart Circ Physiol 294: H901-H908, 2008. First published December 14, 2007; doi:10.1152/ajpheart.00715.2007 [Abstract] [Full Text] [PDF]

Ufuk Olgac, Vartan Kurtcuoglu, and Dimos Poulikakos: Computational modeling of coupled blood-wall mass transport of LDL: effects of local wall shear stress
Am J Physiol Heart Circ Physiol 294: H909-H919, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01082.2007 [Abstract] [Full Text] [PDF]

Kyan J. Allahdadi, Laura C. Duling, Benjimen R. Walker, and Nancy L. Kanagy: Eucapnic intermittent hypoxia augments endothelin-1 vasoconstriction in rats: role of PKC ${delta}$
Am J Physiol Heart Circ Physiol 294: H920-H927, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01264.2007 [Abstract] [Full Text] [PDF]

Andreas N. Kavazis, Joseph M. McClung, David A. Hood, and Scott K. Powers: Exercise induces a cardiac mitochondrial phenotype that resists apoptotic stimuli
Am J Physiol Heart Circ Physiol 294: H928-H935, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01231.2007 [Abstract] [Full Text] [PDF]

Guixiang Zhao, Nam Ho Jeoung, Shawn C. Burgess, Kimberly A. Rosaaen-Stowe, Takeshi Inagaki, Shuaib Latif, John M. Shelton, John McAnally, Rhonda Bassel-Duby, Robert A. Harris, James A. Richardson, and Steven A. Kliewer: Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy
Am J Physiol Heart Circ Physiol 294: H936-H943, 2008. First published December 14, 2007; doi:10.1152/ajpheart.00870.2007 [Abstract] [Full Text] [PDF]

Kazuhiro Yatera, Joanne Hsieh, James C. Hogg, Erin Tranfield, Hisashi Suzuki, Chih-Horng Shih, Ali R. Behzad, Renaud Vincent, and Stephan F. van Eeden: Particulate matter air pollution exposure promotes recruitment of monocytes into atherosclerotic plaques
Am J Physiol Heart Circ Physiol 294: H944-H953, 2008. First published December 14, 2007; doi:10.1152/ajpheart.00406.2007 [Abstract] [Full Text] [PDF]

Lufang Zhou, Hazel Huang, Celvie L. Yuan, Wendy Keung, Gary D. Lopaschuk, and William C. Stanley: Metabolic response to an acute jump in cardiac workload: effects on malonyl-CoA, mechanical efficiency, and fatty acid oxidation
Am J Physiol Heart Circ Physiol 294: H954-H960, 2008. First published December 14, 2007; doi:10.1152/ajpheart.00557.2007 [Abstract] [Full Text] [PDF]

R. Srinivasan, S. Forman, R. A. Quinlan, J. Ohanian, and V. Ohanian: Regulation of contractility by Hsp27 and Hic-5 in rat mesenteric small arteries
Am J Physiol Heart Circ Physiol 294: H961-H969, 2008. First published December 14, 2007; doi:10.1152/ajpheart.00939.2007 [Abstract] [Full Text] [PDF]

Samarjit Das, Istvan Lekli, Manika Das, Gergo Szabo, Judit Varadi, Bela Juhasz, Istvan Bak, Kalanithi Nesaretam, Arpad Tosaki, Saul R. Powell, and Dipak K. Das: Cardioprotection with palm oil tocotrienols: comparision of different isomers
Am J Physiol Heart Circ Physiol 294: H970-H978, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01200.2007 [Abstract] [Full Text] [PDF]

Chian P. Ye, Sheng Zhong Duan, David S. Milstone, and Richard M. Mortensen: G_o controls the hyperpolarization-activated current in embryonic stem cell-derived cardiocytes
Am J Physiol Heart Circ Physiol 294: H979-H985, 2008. First published December 21, 2007; doi:10.1152/ajpheart.00293.2007 [Abstract] [Full Text] [PDF]

Paul Knaapen, Tjeerd Germans, Paolo G. Camici, Ornella E. Rimoldi, Folkert J. ten Cate, Jurrien M. ten Berg, Pieter A. Dijkmans, Ronald Boellaard, Willem G. van Dockum, Marco J. W. Götte, Jos W. R. Twisk, Albert C. van Rossum, Adriaan A. Lammertsma, and Frans C. Visser: Determinants of coronary microvascular dysfunction in symptomatic hypertrophic cardiomyopathy
Am J Physiol Heart Circ Physiol 294: H986-H993, 2008. First published December 21, 2007; doi:10.1152/ajpheart.00233.2007 [Abstract] [Full Text] [PDF]

Min Yang, Jun Wu, Claudio M. Martin, Peter R. Kvietys, and Tao Rui: Important role of p38 MAP kinase/NF- ${kappa}$ B signaling pathway in the sepsis-induced conversion of cardiac myocytes to a proinflammatory phenotype
Am J Physiol Heart Circ Physiol 294: H994-H1001, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01044.2007 [Abstract] [Full Text] [PDF]

Liyun Rao, Yuesheng Ling, Renjie He, April L. Gilbert, Nikolaos G. Frangogiannis, Jianwen Wang, Sherif F. Nagueh, and Dirar S. Khoury: Integrated multimodal-catheter imaging unveils principal relationships among ventricular electrical activity, anatomy, and function
Am J Physiol Heart Circ Physiol 294: H1002-H1009, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01297.2006 [Abstract] [Full Text] [PDF]

Kenneth B. Walsh and Jining Zhang: Neonatal rat cardiac fibroblasts express three types of voltage-gated K⁺ channels: regulation of a transient outward current by protein kinase C
Am J Physiol Heart Circ Physiol 294: H1010-H1017, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01195.2007 [Abstract] [Full Text] [PDF]

Jennifer Cheng, Jing-Song Ou, Harpreet Singh, John R. Falck, Dubasi Narsimhaswamy, Kirkwood A. Pritchard, Jr., and Michal Laniado Schwartzman: 20-Hydroxyeicosatetraenoic acid causes endothelial dysfunction via eNOS uncoupling
Am J Physiol Heart Circ Physiol 294: H1018-H1026, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01172.2007 [Abstract] [Full Text] [PDF]

P. Uttayarat, M. Chen, M. Li, F. D. Allen, R. J. Composto, and P. I. Lelkes: Microtopography and flow modulate the direction of endothelial cell migration
Am J Physiol Heart Circ Physiol 294: H1027-H1035, 2008. First published December 21, 2007; doi:10.1152/ajpheart.00816.2007 [Abstract] [Full Text] [PDF]

Molly S. Bray, Chad A. Shaw, Michael W. S. Moore, Rodrigo A. P. Garcia, Melissa M. Zanquetta, David J. Durgan, William J. Jeong, Ju-Yun Tsai, Heiko Bugger, Dongfang Zhang, Andreas Rohrwasser, Julie H. Rennison, Jason R. B. Dyck, Sheldon E. Litwin, Paul E. Hardin, Chi-Wing Chow, Margaret P. Chandler, E. Dale Abel, and Martin E. Young: Disruption of the circadian clock within the cardiomyocyte influences myocardial contractile function, metabolism, and gene expression
Am J Physiol Heart Circ Physiol 294: H1036-H1047, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01291.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables and Figures]

Masayasu Esaki, Genzou Takemura, Ken-ichiro Kosai, Tomoyuki Takahashi, Shusaku Miyata, Longhu Li, Kazuko Goto, Rumi Maruyama, Hideshi Okada, Hiromitsu Kanamori, Atsushi Ogino, Hiroaki Ushikoshi, Shinya Minatoguchi, Takako Fujiwara, and Hisayoshi Fujiwara: Treatment with an adenoviral vector encoding hepatocyte growth factor mitigates established cardiac dysfunction in doxorubicin-induced cardiomyopathy
Am J Physiol Heart Circ Physiol 294: H1048-H1057, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01102.2007 [Abstract] [Full Text] [PDF]

Johannes Jacobi, Renke Maas, Nada Cordasic, Kilian Koch, Roland E. Schmieder, Rainer H. Böger, and Karl F. Hilgers: Role of asymmetric dimethylarginine for angiotensin II-induced target organ damage in mice
Am J Physiol Heart Circ Physiol 294: H1058-H1066, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01103.2007 [Abstract] [Full Text] [PDF]

Zhi-Hua Zhang, Yang Yu, Yu-Ming Kang, Shun-Guang Wei, and Robert B. Felder: Aldosterone acts centrally to increase brain renin-angiotensin system activity and oxidative stress in normal rats
Am J Physiol Heart Circ Physiol 294: H1067-H1074, 2008. First published December 27, 2007; doi:10.1152/ajpheart.01131.2007 [Abstract] [Full Text] [PDF]

Patricia Rose, Jeffrey Bond, Scott Tighe, Michael J. Toth, Theresa L. Wellman, Eva Maria Briso de Montiano, Martin M. Lewinter, and Karen M. Lounsbury: Genes overexpressed in cerebral arteries following salt-induced hypertensive disease are regulated by angiotensin II, JunB, and CREB
Am J Physiol Heart Circ Physiol 294: H1075-H1085, 2008. First published December 21, 2007; doi:10.1152/ajpheart.00913.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]

INNOVATIVE METHODOLOGY:

Christian Heiss, Richard E. Sievers, Nicolas Amabile, Tony Y. Momma, Qiumei Chen, Shobha Natarajan, Yerem Yeghiazarians, and Matthew L. Springer: In vivo measurement of flow-mediated vasodilation in living rats using high-resolution ultrasound
Am J Physiol Heart Circ Physiol 294: H1086-H1093, 2008. First published November 30, 2007; doi:10.1152/ajpheart.00811.2007 [Abstract] [Full Text] [PDF]

Masakazu Shinohara, Tomoya Yamashita, Hideto Tawa, Masafumi Takeda, Naoto Sasaki, Tomofumi Takaya, Ryuji Toh, Akihisa Takeuchi, Takuji Ohigashi, Kunio Shinohara, Seinosuke Kawashima, Mitsuhiro Yokoyama, Ken-ichi Hirata, and Atsushi Momose: Atherosclerotic plaque imaging using phase-contrast X-ray computed tomography
Am J Physiol Heart Circ Physiol 294: H1094-H1100, 2008. First published December 14, 2007; doi:10.1152/ajpheart.01149.2007 [Abstract] [Full Text] [PDF]

CORRIGENDA:

: Corrigendum
Am J Physiol Heart Circ Physiol 294: H1101-H1101, 2008; doi:10.1152/ajpheart.zh4-8123-corr.2008 [Full Text] [PDF]

Cover Caption:

Cover

Cover: Rotigaptide prevents ischemia-induced dephosphorylation of connexin43 in cardiac gap junctions. Confocal immunofluorescence images show no change in the distribution, pattern, or quantity of Cx43 signal in rotigaptide-treated hearts during ischemia. See Kjølbye AL, Dikshteyn M, Eloff BC, Deschênes I, Rosenbaum DS. Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans. Am J Physiol Heart Circ Physiol 294: H41–H49, 2008.