AJP - Heart and Circulatory Physiology -- Table of Contents (March 1 2008, 294 [3])

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CALL FOR PAPERS:

Susann Patschan, Jun Chen, Alla Polotskaia, Natalja Mendelev, Jennifer Cheng, Daniel Patschan, and Michael S. Goligorsky: Lipid mediators of autophagy in stress-induced premature senescence of endothelial cells
Am J Physiol Heart Circ Physiol 294: H1119-H1129, 2008. First published January 18, 2008; doi:10.1152/ajpheart.00713.2007 [Abstract] [Full Text] [PDF]

INVITED REVIEW:

Rhian M. Touyz: Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension
Am J Physiol Heart Circ Physiol 294: H1103-H1118, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00903.2007 [Abstract] [Full Text] [PDF]

EDITORIAL FOCUS:

Stefan Hein, Sawa Kostin, and Jutta Schaper: mRNA cargo no longer on time
Am J Physiol Heart Circ Physiol 294: H1130-H1132, 2008. First published January 18, 2008; doi:10.1152/ajpheart.91528.2007 [Full Text] [PDF]

Pál Pacher and Zoltán Ungvári: Pleiotropic effects of the CB₂ cannabinoid receptor activation on human monocyte migration: implications for atherosclerosis and inflammatory diseases
Am J Physiol Heart Circ Physiol 294: H1133-H1134, 2008. First published January 18, 2008; doi:10.1152/ajpheart.00020.2008 [Full Text] [PDF]

ARTICLES:

Dimitri Scholz, Catalin F. Baicu, William J. Tuxworth, Lin Xu, Harinath Kasiganesan, Donald R. Menick, and George Cooper, IV: Microtubule-dependent distribution of mRNA in adult cardiocytes
Am J Physiol Heart Circ Physiol 294: H1135-H1144, 2008. First published January 4, 2008; doi:10.1152/ajpheart.01275.2007 [Abstract] [Full Text] [PDF] [Supplemental Videos]

Fabrizio Montecucco, Fabienne Burger, François Mach, and Sabine Steffens: CB₂ cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways
Am J Physiol Heart Circ Physiol 294: H1145-H1155, 2008. First published January 4, 2008; doi:10.1152/ajpheart.01328.2007 [Abstract] [Full Text] [PDF]

Ran Reshef, Doron Schwartz, Merav Ingbir, Alexander Shtabsky, Tamara Chernichovski, Benjamin A. Isserlin, Gil Chernin, Yoram Levo, and Idit F. Schwartz: A profound decrease in maternal arginine uptake provokes endothelial nitration in the pregnant rat
Am J Physiol Heart Circ Physiol 294: H1156-H1163, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01051.2007 [Abstract] [Full Text] [PDF]

Takashi Sato, Tomoko Ohkusa, Haruo Honjo, Shinsuke Suzuki, Masa-aki Yoshida, Yuko S. Ishiguro, Harumichi Nakagawa, Masatoshi Yamazaki, Masafumi Yano, Itsuo Kodama, and Masunori Matsuzaki: Altered expression of connexin43 contributes to the arrhythmogenic substrate during the development of heart failure in cardiomyopathic hamster
Am J Physiol Heart Circ Physiol 294: H1164-H1173, 2008. First published December 7, 2007; doi:10.1152/ajpheart.00960.2007 [Abstract] [Full Text] [PDF] [Supplemental Videos]

Matt M. Riordan, Edward P. Weiss, Timothy E. Meyer, Ali A. Ehsani, Susan B. Racette, Dennis T. Villareal, Luigi Fontana, John O. Holloszy, and Sándor J. Kovács: The effects of caloric restriction- and exercise-induced weight loss on left ventricular diastolic function
Am J Physiol Heart Circ Physiol 294: H1174-H1182, 2008. First published December 27, 2007; doi:10.1152/ajpheart.01236.2007 [Abstract] [Full Text] [PDF]

Kristen M. Park, Mario Trucillo, Nicolas Serban, Richard A. Cohen, and Victoria M. Bolotina: Role of iPLA₂ and store-operated channels in agonist-induced Ca²⁺ influx and constriction in cerebral, mesenteric, and carotid arteries
Am J Physiol Heart Circ Physiol 294: H1183-H1187, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01148.2007 [Abstract] [Full Text] [PDF]

R. H. Adamson, J. C. Ly, R. K. Sarai, J. F. Lenz, A. Altangerel, D. Drenckhahn, and F. E. Curry: Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery
Am J Physiol Heart Circ Physiol 294: H1188-H1196, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00937.2007 [Abstract] [Full Text] [PDF]

Evren U. Azeloglu, Michael B. Albro, Vikrum A. Thimmappa, Gerard A. Ateshian, and Kevin D. Costa: Heterogeneous transmural proteoglycan distribution provides a mechanism for regulating residual stresses in the aorta
Am J Physiol Heart Circ Physiol 294: H1197-H1205, 2008. First published December 21, 2007; doi:10.1152/ajpheart.01027.2007 [Abstract] [Full Text] [PDF]

Gabriel Laurent, Gordon Moe, Xudong Hu, Howard Leong-Poi, Kim A. Connelly, Petsy Pui-Sze So, Andrew Ramadeen, Liia Doumanovskaia, Andrea Konig, Judy Trogadis, David Courtman, Bradley Strauss, and Paul Dorian: Experimental studies of atrial fibrillation: a comparison of two pacing models
Am J Physiol Heart Circ Physiol 294: H1206-H1215, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00999.2007 [Abstract] [Full Text] [PDF]

Jiun-Jr Wang, Nigel G. Shrive, Kim H. Parker, and John V. Tyberg: Effects of vasoconstriction and vasodilatation on LV and segmental circulatory energetics
Am J Physiol Heart Circ Physiol 294: H1216-H1225, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00983.2007 [Abstract] [Full Text] [PDF]

Umesh Sharma, Nour-Eddine Rhaleb, Saraswati Pokharel, Pamela Harding, Saman Rasoul, Hongmei Peng, and Oscar A. Carretero: Novel anti-inflammatory mechanisms of N-Acetyl-Ser-Asp-Lys-Pro in hypertension-induced target organ damage
Am J Physiol Heart Circ Physiol 294: H1226-H1232, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00305.2007 [Abstract] [Full Text] [PDF]

C. Angeloni, E. Leoncini, M. Malaguti, S. Angelini, P. Hrelia, and S. Hrelia: Role of quercetin in modulating rat cardiomyocyte gene expression profile
Am J Physiol Heart Circ Physiol 294: H1233-H1243, 2008. First published January 4, 2008; doi:10.1152/ajpheart.01091.2007 [Abstract] [Full Text] [PDF]

Christopher J. Mingone, Mansoor Ahmad, Sachin A. Gupte, Joseph L. Chow, and Michael S. Wolin: Heme oxygenase-1 induction depletes heme and attenuates pulmonary artery relaxation and guanylate cyclase activation by nitric oxide
Am J Physiol Heart Circ Physiol 294: H1244-H1250, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00846.2007 [Abstract] [Full Text] [PDF]

David B. Murray, Jason D. Gardner, Gregory L. Brower, and Joseph S. Janicki: Effects of nonselective endothelin-1 receptor antagonism on cardiac mast cell-mediated ventricular remodeling in rats
Am J Physiol Heart Circ Physiol 294: H1251-H1257, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00622.2007 [Abstract] [Full Text] [PDF]

Luminita H. Pojoga, Tham M. Yao, Sumi Sinha, Reagan L. Ross, Jeffery C. Lin, Joseph D. Raffetto, Gail K. Adler, Gordon H. Williams, and Raouf A. Khalil: Effect of dietary sodium on vasoconstriction and eNOS-mediated vascular relaxation in caveolin-1-deficient mice
Am J Physiol Heart Circ Physiol 294: H1258-H1265, 2008. First published January 4, 2008; doi:10.1152/ajpheart.01014.2007 [Abstract] [Full Text] [PDF]

Mohamed A. Omar, Heather Fraser, and Alexander S. Clanachan: Ischemia-induced activation of AMPK does not increase glucose uptake in glycogen-replete isolated working rat hearts
Am J Physiol Heart Circ Physiol 294: H1266-H1273, 2008. First published January 4, 2008; doi:10.1152/ajpheart.01087.2007 [Abstract] [Full Text] [PDF]

Xinhua Yan, Adam J. T. Schuldt, Robert L. Price, Ivo Amende, Fen-Fen Liu, Katashi Okoshi, Kalon K. L. Ho, Adèle J. Pope, Thomas K. Borg, Beverly H. Lorell, and James P. Morgan: Pressure overload-induced hypertrophy in transgenic mice selectively overexpressing AT₂ receptors in ventricular myocytes
Am J Physiol Heart Circ Physiol 294: H1274-H1281, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00174.2006 [Abstract] [Full Text] [PDF]

Laura R. La Bonte, Grace Davis-Gorman, Gregory L. Stahl, and Paul F. McDonagh: Complement inhibition reduces injury in the type 2 diabetic heart following ischemia and reperfusion
Am J Physiol Heart Circ Physiol 294: H1282-H1290, 2008. First published January 4, 2008; doi:10.1152/ajpheart.00843.2007 [Abstract] [Full Text] [PDF]

Ruiping Huang, Amrita Karve, Ibrahim Shah, Mark C. Bowers, Donald J. DiPette, Scott C. Supowit, and George S. Abela: Deletion of the mouse ${alpha}$ -calcitonin gene-related peptide gene increases the vulnerability of the heart to ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol 294: H1291-H1297, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00749.2007 [Abstract] [Full Text] [PDF]

Shijun Huang, Eugene Patterson, Xichun Yu, Marion W. Garrett, Isabel De Aos, and David C. Kem: Proteasome inhibition 1 h following ischemia protects GRK2 and prevents malignant ventricular tachyarrhythmias and SCD in a model of myocardial infarction
Am J Physiol Heart Circ Physiol 294: H1298-H1303, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00765.2007 [Abstract] [Full Text] [PDF]

Javier A. Sala-Mercado, Masashi Ichinose, Robert L. Hammond, Matthew Coutsos, Tomoko Ichinose, Marco Pallante, Ferdinando Iellamo, and Donal S. O'Leary: Spontaneous baroreflex control of heart rate versus cardiac output: altered coupling in heart failure
Am J Physiol Heart Circ Physiol 294: H1304-H1309, 2008. First published January 11, 2008; doi:10.1152/ajpheart.01186.2007 [Abstract] [Full Text] [PDF]

Masashi Ichinose, Javier A. Sala-Mercado, Donal S. O'Leary, Robert L. Hammond, Matthew Coutsos, Tomoko Ichinose, Marco Pallante, and Ferdinando Iellamo: Spontaneous baroreflex control of cardiac output during dynamic exercise, muscle metaboreflex activation, and heart failure
Am J Physiol Heart Circ Physiol 294: H1310-H1316, 2008. First published January 11, 2008; doi:10.1152/ajpheart.01187.2007 [Abstract] [Full Text] [PDF]

Jasna Marinovic, Marko Ljubkovic, Anna Stadnicka, Zeljko J. Bosnjak, and Martin Bienengraeber: Role of sarcolemmal ATP-sensitive potassium channel in oxidative stress-induced apoptosis: mitochondrial connection
Am J Physiol Heart Circ Physiol 294: H1317-H1325, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00840.2007 [Abstract] [Full Text] [PDF]

Joseph Uzarski, Megan B. Drelles, Sara E. Gibbs, Emily L. Ongstad, Julie C. Goral, Katherine K. McKeown, Alisha M. Raehl, Melissa A. Roberts, Bronislaw Pytowski, Martyn R. Smith, and Jeremy Goldman: The resolution of lymphedema by interstitial flow in the mouse tail skin
Am J Physiol Heart Circ Physiol 294: H1326-H1334, 2008. First published January 18, 2008; doi:10.1152/ajpheart.00900.2007 [Abstract] [Full Text] [PDF]

Ming Zhu, Agnieszka A. Gach, GongXin Liu, Xiaomei Xu, Chee Chew Lim, Julie X. Zhang, Lan Mao, Kurt Chuprun, Walter J. Koch, Ronglih Liao, Gideon Koren, Burns C. Blaxall, and Ulrike Mende: Enhanced calcium cycling and contractile function in transgenic hearts expressing constitutively active G ${alpha}$ _o* protein
Am J Physiol Heart Circ Physiol 294: H1335-H1347, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00584.2007 [Abstract] [Full Text] [PDF]

Yuttana Chawengsub, Nitin T. Aggarwal, Kasem Nithipatikom, Kathryn M. Gauthier, Siddam Anjaiah, Bruce D. Hammock, John R. Falck, and William B. Campbell: Identification of 15-hydroxy-11,12-epoxyeicosatrienoic acid as a vasoactive 15-lipoxygenase metabolite in rabbit aorta
Am J Physiol Heart Circ Physiol 294: H1348-H1356, 2008. First published January 11, 2008; doi:10.1152/ajpheart.01326.2007 [Abstract] [Full Text] [PDF]

Marco Guazzi, Ross Arena, and Maurizio D. Guazzi: Evolving changes in lung interstitial fluid content after acute myocardial infarction: mechanisms and pathophysiological correlates
Am J Physiol Heart Circ Physiol 294: H1357-H1364, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00866.2007 [Abstract] [Full Text] [PDF]

Bela Juhasz, Mahesh Thirunavukkarasu, Rima Pant, Lijun Zhan, Suresh Varma Penumathsa, Eric R. Secor, Jr., Sapna Srivastava, Utpal Raychaudhuri, Venugopal P. Menon, Hajime Otani, Roger S. Thrall, and Nilanjana Maulik: Bromelain induces cardioprotection against ischemia-reperfusion injury through Akt/FOXO pathway in rat myocardium
Am J Physiol Heart Circ Physiol 294: H1365-H1370, 2008. First published January 11, 2008; doi:10.1152/ajpheart.01005.2007 [Abstract] [Full Text] [PDF]

Xiaobin Luo, Jiening Xiao, Huixian Lin, Yanjie Lu, Baofeng Yang, and Zhiguo Wang: Genomic structure, transcriptional control, and tissue distribution of HERG1 and KCNQ1 genes
Am J Physiol Heart Circ Physiol 294: H1371-H1380, 2008. First published January 11, 2008; doi:10.1152/ajpheart.01026.2007 [Abstract] [Full Text] [PDF]

George Osol, Gerard Celia, Natalia Gokina, Carolyn Barron, Edward Chien, Maurizio Mandala, Leonid Luksha, and Karolina Kublickiene: Placental growth factor is a potent vasodilator of rat and human resistance arteries
Am J Physiol Heart Circ Physiol 294: H1381-H1387, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00922.2007 [Abstract] [Full Text] [PDF]

Jyothish B. Pillai, Martin Chen, Senthilkumar B. Rajamohan, Sadhana Samant, Vinodkumar B. Pillai, Madhu Gupta, and Mahesh P. Gupta: Activation of SIRT1, a class III histone deacetylase, contributes to fructose feeding-mediated induction of the ${alpha}$ -myosin heavy chain expression
Am J Physiol Heart Circ Physiol 294: H1388-H1397, 2008. First published January 11, 2008; doi:10.1152/ajpheart.01339.2007 [Abstract] [Full Text] [PDF]

Fadi N. Salloum, Antonio Abbate, Anindita Das, Jon-Erik Houser, Colin A. Mudrick, Ian Z. Qureshi, Nicholas N. Hoke, Sion K. Roy, William R. Brown, Shashi Prabhakar, and Rakesh C. Kukreja: Sildenafil (Viagra) attenuates ischemic cardiomyopathy and improves left ventricular function in mice
Am J Physiol Heart Circ Physiol 294: H1398-H1406, 2008. First published January 25, 2008; doi:10.1152/ajpheart.91438.2007 [Abstract] [Full Text] [PDF]

Ronald M. Lynch, Craig S. Weber, Kevin D. Nullmeyer, Edwin D. W. Moore, and Richard J. Paul: Clearance of store-released Ca²⁺ by the Na⁺-Ca²⁺ exchanger is diminished in aortic smooth muscle from Na⁺-K⁺-ATPase ${alpha}$ ₂-isoform gene-ablated mice
Am J Physiol Heart Circ Physiol 294: H1407-H1416, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00855.2007 [Abstract] [Full Text] [PDF]

Carlos de Diego, Rakesh K. Pai, Amish S. Dave, Adam Lynch, Mya Thu, Fuhua Chen, Lai-Hua Xie, James N. Weiss, and Miguel Valderrábano: Spatially discordant alternans in cardiomyocyte monolayers
Am J Physiol Heart Circ Physiol 294: H1417-H1425, 2008. First published January 25, 2008; doi:10.1152/ajpheart.01233.2007 [Abstract] [Full Text] [PDF]

M. A. Hassan Talukder, Anuradha Kalyanasundaram, Li Zuo, Murugesan Velayutham, Yoshinori Nishijima, Muthu Periasamy, and Jay L. Zweier: Is reduced SERCA2a expression detrimental or beneficial to postischemic cardiac function and injury? Evidence from heterozygous SERCA2a knockout mice
Am J Physiol Heart Circ Physiol 294: H1426-H1434, 2008. First published January 18, 2008; doi:10.1152/ajpheart.01016.2007 [Abstract] [Full Text] [PDF]

Caroline Morin, Christelle Guibert, Marco Sirois, Vincent Echave, Marcio M. Gomes, and Eric Rousseau: Effects of ${omega}$ -hydroxylase product on distal human pulmonary arteries
Am J Physiol Heart Circ Physiol 294: H1435-H1443, 2008. First published January 18, 2008; doi:10.1152/ajpheart.01115.2007 [Abstract] [Full Text] [PDF]

Amanda J. Zatta, Hajime Kin, Darice Yoshishige, Rong Jiang, Ningping Wang, James G. Reeves, James Mykytenko, Robert A. Guyton, Zhi-Qing Zhao, James L. Caffrey, and Jakob Vinten-Johansen: Evidence that cardioprotection by postconditioning involves preservation of myocardial opioid content and selective opioid receptor activation
Am J Physiol Heart Circ Physiol 294: H1444-H1451, 2008. First published January 18, 2008; doi:10.1152/ajpheart.01279.2006 [Abstract] [Full Text] [PDF]

Rgia A. Othman, Miyoung Suh, Gabor Fischer, Nazila Azordegan, Natalie Riediger, Khuong Le, Davinder S. Jassal, and Mohammed H. Moghadasian: A comparison of the effects of fish oil and flaxseed oil on cardiac allograft chronic rejection in rats
Am J Physiol Heart Circ Physiol 294: H1452-H1458, 2008. First published January 25, 2008; doi:10.1152/ajpheart.01280.2007 [Abstract] [Full Text] [PDF]

Ilka Pinz, Sanford E. Ostroy, Kirsten Hoyer, Hanna Osinska, Jeffrey Robbins, Jeffery D. Molkentin, and Joanne S. Ingwall: Calcineurin-induced energy wasting in a transgenic mouse model of heart failure
Am J Physiol Heart Circ Physiol 294: H1459-H1466, 2008. First published January 11, 2008; doi:10.1152/ajpheart.00911.2007 [Abstract] [Full Text] [PDF]

Kathryn M. Gauthier, Yuttana Chawengsub, Daniel H. Goldman, Raymond E. Conrow, Siddam Anjaiah, J. R. Falck, and William B. Campbell: 11(R),12(S),15(S)-trihydroxyeicosa-5(Z),8(Z),13(E)-trienoic acid: an endothelium-derived 15-lipoxygenase metabolite that relaxes rabbit aorta
Am J Physiol Heart Circ Physiol 294: H1467-H1472, 2008. First published January 18, 2008; doi:10.1152/ajpheart.01052.2007 [Abstract] [Full Text] [PDF]

Honglan Wang, Mark J. Kohr, Debra G. Wheeler, and Mark T. Ziolo: Endothelial nitric oxide synthase decreases β-adrenergic responsiveness via inhibition of the L-type Ca²⁺ current
Am J Physiol Heart Circ Physiol 294: H1473-H1480, 2008. First published January 18, 2008; doi:10.1152/ajpheart.01249.2007 [Abstract] [Full Text] [PDF]

Kiyoshi Kotani, Kiyoshi Takamasu, Yasuhiko Jimbo, and Yoshiharu Yamamoto: Postural-induced phase shift of respiratory sinus arrhythmia and blood pressure variations: insight from respiratory-phase domain analysis
Am J Physiol Heart Circ Physiol 294: H1481-H1489, 2008. First published January 25, 2008; doi:10.1152/ajpheart.00680.2007 [Abstract] [Full Text] [PDF]

Huei-Ping Tzeng, Jinping Fan, Jesus G. Vallejo, Jian Wen Dong, Xiongwen Chen, Steven R. Houser, and Douglas L. Mann: Negative inotropic effects of high-mobility group box 1 protein in isolated contracting cardiac myocytes
Am J Physiol Heart Circ Physiol 294: H1490-H1496, 2008. First published January 25, 2008; doi:10.1152/ajpheart.00910.2007 [Abstract] [Full Text] [PDF]

CORRIGENDA:

: Corrigendum
Am J Physiol Heart Circ Physiol 294: H1501-H1501, 2008; doi:10.1152/ajpheart.zh4-8142-corr.2008 [Full Text] [PDF]

: Corrigendum
Am J Physiol Heart Circ Physiol 294: 1502-1502, 2008; doi:10.1152/ajpheart.zh4-8140-corr.2008 [Full Text] [PDF]

REPORTS:

Eric R. Gross, Anna K. Hsu, and Garrett J. Gross: Delayed cardioprotection afforded by the glycogen synthase kinase 3 inhibitor SB-216763 occurs via a K_ATP- and MPTP-dependent mechanism at reperfusion
Am J Physiol Heart Circ Physiol 294: H1497-H1500, 2008. First published January 25, 2008; doi:10.1152/ajpheart.01381.2007 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Rotigaptide prevents ischemia-induced dephosphorylation of connexin43 in cardiac gap junctions. Confocal immunofluorescence images show no change in the distribution, pattern, or quantity of Cx43 signal in rotigaptide-treated hearts during ischemia. See Kjølbye AL, Dikshteyn M, Eloff BC, Deschênes I, Rosenbaum DS. Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans. Am J Physiol Heart Circ Physiol 294: H41–H49, 2008.