AJP - Heart and Circulatory Physiology -- Table of Contents (June 1 2008, 294 [6])

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Aditya Goel, Der Thor, Leigh Anderson, and Roshanak Rahimian: Sexual dimorphism in rabbit aortic endothelial function under acute hyperglycemic conditions and gender-specific responses to acute 17β-estradiol
Am J Physiol Heart Circ Physiol 294: H2411-H2420, 2008. First published March 7, 2008; doi:10.1152/ajpheart.01217.2007 [Abstract] [Full Text] [PDF]

Nina D. Ullrich, Andree Krust, Peter Collins, and Kenneth T. MacLeod: Genomic deletion of estrogen receptors ER ${alpha}$ and ERβ does not alter estrogen-mediated inhibition of Ca²⁺ influx and contraction in murine cardiomyocytes
Am J Physiol Heart Circ Physiol 294: H2421-H2427, 2008. First published April 25, 2008; doi:10.1152/ajpheart.01225.2007 [Abstract] [Full Text] [PDF]

ARTICLES:

Ketaki V. Desai, Glen A. Laine, Randolph H. Stewart, Charles S. Cox, Jr., Christopher M. Quick, Steven J. Allen, and Uwe M. Fischer: Mechanics of the left ventricular myocardial interstitium: effects of acute and chronic myocardial edema
Am J Physiol Heart Circ Physiol 294: H2428-H2434, 2008. First published March 28, 2008; doi:10.1152/ajpheart.00860.2007 [Abstract] [Full Text] [PDF]

Navdeep Ojha, Sashwati Roy, Jared Radtke, Orlando Simonetti, Surya Gnyawali, Jay L. Zweier, Periannan Kuppusamy, and Chandan K. Sen: Characterization of the structural and functional changes in the myocardium following focal ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol 294: H2435-H2443, 2008. First published March 28, 2008; doi:10.1152/ajpheart.01190.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]

Min Li, Lih Kuo, and John N. Stallone: Estrogen potentiates constrictor prostanoid function in female rat aorta by upregulation of cyclooxygenase-2 and thromboxane pathway expression
Am J Physiol Heart Circ Physiol 294: H2444-H2455, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01121.2007 [Abstract] [Full Text] [PDF]

David J. Santone, Rohan Shahani, Barry B. Rubin, Alex D. Romaschin, and Thomas F. Lindsay: Mast cell stabilization improves cardiac contractile function following hemorrhagic shock and resuscitation
Am J Physiol Heart Circ Physiol 294: H2456-H2464, 2008. First published April 4, 2008; doi:10.1152/ajpheart.00925.2007 [Abstract] [Full Text] [PDF]

Audrey Borghi-Silva, Cláudia Carrascosa, Cristino Carneiro Oliveira, Adriano C. Barroco, Danilo C. Berton, Debora Vilaça, Edgar B. Lira-Filho, Dirceu Ribeiro, Luiz Eduardo Nery, and J. Alberto Neder: Effects of respiratory muscle unloading on leg muscle oxygenation and blood volume during high-intensity exercise in chronic heart failure
Am J Physiol Heart Circ Physiol 294: H2465-H2472, 2008. First published March 28, 2008; doi:10.1152/ajpheart.91520.2007 [Abstract] [Full Text] [PDF]

Seiji Matsuhisa, Hajime Otani, Toru Okazaki, Koji Yamashita, Yuzo Akita, Daisuke Sato, Akira Moriguchi, Hiroji Imamura, and Toshiji Iwasaka: Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart
Am J Physiol Heart Circ Physiol 294: H2473-H2479, 2008. First published April 4, 2008; doi:10.1152/ajpheart.91533.2007 [Abstract] [Full Text] [PDF]

Robert B. Hinton, Jr., Christina M. Alfieri, Sandra A. Witt, Betty J. Glascock, Philip R. Khoury, D. Woodrow Benson, and Katherine E. Yutzey: Mouse heart valve structure and function: echocardiographic and morphometric analyses from the fetus through the aged adult
Am J Physiol Heart Circ Physiol 294: H2480-H2488, 2008. First published April 4, 2008; doi:10.1152/ajpheart.91431.2007 [Abstract] [Full Text] [PDF]

Ian N. Bratz, Gregory M. Dick, Johnathan D. Tune, Jason M. Edwards, Zachary P. Neeb, U. Deniz Dincer, and Michael Sturek: Impaired capsaicin-induced relaxation of coronary arteries in a porcine model of the metabolic syndrome
Am J Physiol Heart Circ Physiol 294: H2489-H2496, 2008. First published April 4, 2008; doi:10.1152/ajpheart.01191.2007 [Abstract] [Full Text] [PDF]

Ramesh Saeedi, Hannah L. Parsons, Richard B. Wambolt, Kim Paulson, Vijay Sharma, Jason R. B. Dyck, Roger W. Brownsey, and Michael F. Allard: Metabolic actions of metformin in the heart can occur by AMPK-independent mechanisms
Am J Physiol Heart Circ Physiol 294: H2497-H2506, 2008. First published March 28, 2008; doi:10.1152/ajpheart.00873.2007 [Abstract] [Full Text] [PDF]

Eiji Takahashi: Anoxic cell core can promote necrotic cell death in cardiomyocytes at physiological extracellular PO₂
Am J Physiol Heart Circ Physiol 294: H2507-H2515, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00168.2008 [Abstract] [Full Text] [PDF]

Jeffrey G. Williams, Caroline Ojaimi, Khaled Qanud, Suhua Zhang, Xiaobin Xu, Fabio A. Recchia, and Thomas H. Hintze: Coronary nitric oxide production controls cardiac substrate metabolism during pregnancy in the dog
Am J Physiol Heart Circ Physiol 294: H2516-H2523, 2008. First published April 18, 2008; doi:10.1152/ajpheart.01196.2007 [Abstract] [Full Text] [PDF]

Steven M. Kerfoot, Graciela Andonegui, Claudine S. Bonder, and Lixin Liu: Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo
Am J Physiol Heart Circ Physiol 294: H2524-H2534, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00984.2007 [Abstract] [Full Text] [PDF]

David G. Edwards, Matthew S. Roy, and Raju Y. Prasad: Wave reflection augments central systolic and pulse pressures during facial cooling
Am J Physiol Heart Circ Physiol 294: H2535-H2539, 2008. First published April 11, 2008; doi:10.1152/ajpheart.01369.2007 [Abstract] [Full Text] [PDF]

Chen Wang, Jun-Feng Du, Feng Wu, and Hai-Chang Wang: Apelin decreases the SR Ca²⁺ content but enhances the amplitude of [Ca²⁺]_i transient and contractions during twitches in isolated rat cardiac myocytes
Am J Physiol Heart Circ Physiol 294: H2540-H2546, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00046.2008 [Abstract] [Full Text] [PDF]

Qin-hui Tuo, Heng Zeng, Amanda Stinnett, Heidi Yu, Judy L. Aschner, Daun-Fang Liao, and Jian-Xiong Chen: Critical role of angiopoietins/Tie-2 in hyperglycemic exacerbation of myocardial infarction and impaired angiogenesis
Am J Physiol Heart Circ Physiol 294: H2547-H2557, 2008. First published April 11, 2008; doi:10.1152/ajpheart.01250.2007 [Abstract] [Full Text] [PDF]

Eva Jebelovszki, Csaba Kiraly, Nora Erdei, Attila Feher, Eniko T. Pasztor, Ibolya Rutkai, Tamas Forster, Istvan Edes, Akos Koller, and Zsolt Bagi: High-fat diet-induced obesity leads to increased NO sensitivity of rat coronary arterioles: role of soluble guanylate cyclase activation
Am J Physiol Heart Circ Physiol 294: H2558-H2564, 2008. First published April 11, 2008; doi:10.1152/ajpheart.01198.2007 [Abstract] [Full Text] [PDF]

Linda J. Wang and Eric A. Sobie: Mathematical model of the neonatal mouse ventricular action potential
Am J Physiol Heart Circ Physiol 294: H2565-H2575, 2008. First published April 11, 2008; doi:10.1152/ajpheart.01376.2007 [Abstract] [Full Text] [PDF] [Supplemental Materials]

Manoj Gandhi, Barry A. Finegan, and Alexander S. Clanachan: Role of glucose metabolism in the recovery of postischemic LV mechanical function: effects of insulin and other metabolic modulators
Am J Physiol Heart Circ Physiol 294: H2576-H2586, 2008. First published April 11, 2008; doi:10.1152/ajpheart.00942.2007 [Abstract] [Full Text] [PDF]

James G. Ryall, Jonathan D. Schertzer, Kate T. Murphy, Andrew M. Allen, and Gordon S. Lynch: Chronic β₂-adrenoceptor stimulation impairs cardiac relaxation via reduced SR Ca²⁺-ATPase protein and activity
Am J Physiol Heart Circ Physiol 294: H2587-H2595, 2008. First published April 11, 2008; doi:10.1152/ajpheart.00985.2007 [Abstract] [Full Text] [PDF]

Tsuneo Ogawa, John P. Veinot, Mercedes L. Kuroski de Bold, Tina Georgalis, and Adolfo J. de Bold: Angiotensin II receptor antagonism reverts the selective cardiac BNP upregulation and secretion observed in myocarditis
Am J Physiol Heart Circ Physiol 294: H2596-H2603, 2008. First published April 11, 2008; doi:10.1152/ajpheart.00215.2008 [Abstract] [Full Text] [PDF] [Supplemental Tables]

Jianfeng Du, Jing Liu, Han-Zhong Feng, M. M. Hossain, Nariman Gobara, Chi Zhang, Yuejin Li, Pierre-Yves Jean-Charles, Jian-Ping Jin, and Xu-Pei Huang: Impaired relaxation is the main manifestation in transgenic mice expressing a restrictive cardiomyopathy mutation, R193H, in cardiac TnI
Am J Physiol Heart Circ Physiol 294: H2604-H2613, 2008. First published April 11, 2008; doi:10.1152/ajpheart.91506.2007 [Abstract] [Full Text] [PDF]

Jewell A. Jessup, Aaron J. Trask, Mark C. Chappell, Sayaka Nagata, Johji Kato, Kazuo Kitamura, and Carlos M. Ferrario: Localization of the novel angiotensin peptide, angiotensin-(1-12), in heart and kidney of hypertensive and normotensive rats
Am J Physiol Heart Circ Physiol 294: H2614-H2618, 2008. First published April 11, 2008; doi:10.1152/ajpheart.91521.2007 [Abstract] [Full Text] [PDF]

Ryan M. Wolfort, Karen Y. Stokes, and D. Neil Granger: CD4+ T lymphocytes mediate hypercholesterolemia-induced endothelial dysfunction via a NAD(P)H oxidase-dependent mechanism
Am J Physiol Heart Circ Physiol 294: H2619-H2626, 2008. First published April 11, 2008; doi:10.1152/ajpheart.00989.2007 [Abstract] [Full Text] [PDF] [Retraction]

Wen-Hong Kan, Jun-Te Hsu, Zheng-Feng Ba, Martin G. Schwacha, Jianguo Chen, Mashkoor A. Choudhry, Kirby I. Bland, and Irshad H. Chaudry: p38 MAPK-dependent eNOS upregulation is critical for 17β-estradiol-mediated cardioprotection following trauma-hemorrhage
Am J Physiol Heart Circ Physiol 294: H2627-H2636, 2008. First published April 11, 2008; doi:10.1152/ajpheart.91444.2007 [Abstract] [Full Text] [PDF]

Qilin Yu, Tiffany Nguyen, Mourad Ogbi, Robert W. Caldwell, and John A. Johnson: Differential loss of cytochrome-c oxidase subunits in ischemia-reperfusion injury: exacerbation of COI subunit loss by PKC- ${varepsilon}$ inhibition
Am J Physiol Heart Circ Physiol 294: H2637-H2645, 2008. First published April 11, 2008; doi:10.1152/ajpheart.91476.2007 [Abstract] [Full Text] [PDF]

Stephen B. Marko and Deborah H. Damon: VEGF promotes vascular sympathetic innervation
Am J Physiol Heart Circ Physiol 294: H2646-H2652, 2008. First published April 11, 2008; doi:10.1152/ajpheart.00291.2008 [Abstract] [Full Text] [PDF]

K. Shivakumar, S. J. Sollott, M. Sangeetha, S. Sapna, B. Ziman, S. Wang, and E. G. Lakatta: Paracrine effects of hypoxic fibroblast-derived factors on the MPT-ROS threshold and viability of adult rat cardiac myocytes
Am J Physiol Heart Circ Physiol 294: H2653-H2658, 2008. First published April 11, 2008; doi:10.1152/ajpheart.91443.2007 [Abstract] [Full Text] [PDF]

Vincent G. DeMarco, Javad Habibi, Adam T. Whaley-Connell, Rebecca I. Schneider, Randall L. Heller, James P. Bosanquet, Melvin R. Hayden, Kimberly Delcour, S. A. Cooper, Bradley T. Andresen, James R. Sowers, and Kevin C. Dellsperger: Oxidative stress contributes to pulmonary hypertension in the transgenic (mRen2)27 rat
Am J Physiol Heart Circ Physiol 294: H2659-H2668, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00953.2007 [Abstract] [Full Text] [PDF]

K. E. Pyke, V. Poitras, and M. E. Tschakovsky: Brachial artery flow-mediated dilation during handgrip exercise: evidence for endothelial transduction of the mean shear stimulus
Am J Physiol Heart Circ Physiol 294: H2669-H2679, 2008. First published April 11, 2008; doi:10.1152/ajpheart.01372.2007 [Abstract] [Full Text] [PDF]

Mohammad N. Jameel, Xiaohong Wang, Marcel H. J. Eijgelshoven, Abdul Mansoor, and Jianyi Zhang: Transmural distribution of metabolic abnormalities and glycolytic activity during dobutamine-induced demand ischemia
Am J Physiol Heart Circ Physiol 294: H2680-H2686, 2008. First published April 18, 2008; doi:10.1152/ajpheart.01383.2007 [Abstract] [Full Text] [PDF]

Zlatina Naydenova, Jennifer B. Rose, and Imogen R. Coe: Inosine and equilibrative nucleoside transporter 2 contribute to hypoxic preconditioning in the murine cardiomyocyte HL-1 cell line
Am J Physiol Heart Circ Physiol 294: H2687-H2692, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00251.2007 [Abstract] [Full Text] [PDF]

Jian Cui, Raman Moradkhan, Vernon Mascarenhas, Afsana Momen, and Lawrence I. Sinoway: Cyclooxygenase inhibition attenuates sympathetic responses to muscle stretch in humans
Am J Physiol Heart Circ Physiol 294: H2693-H2700, 2008. First published April 25, 2008; doi:10.1152/ajpheart.91505.2007 [Abstract] [Full Text] [PDF]

L. Leatherbury, Q. Yu, B. Chatterjee, D. L. Walker, Z. Yu, X. Tian, and C. W. Lo: A novel mouse model of X-linked cardiac hypertrophy
Am J Physiol Heart Circ Physiol 294: H2701-H2711, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00160.2007 [Abstract] [Full Text] [PDF] [Supplemental Videos]

Fanrong Yao, Colin Sumners, Stephen T. O'Rourke, and Chengwen Sun: Angiotensin II increases GABA_B receptor expression in nucleus tractus solitarii of rats
Am J Physiol Heart Circ Physiol 294: H2712-H2720, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00729.2007 [Abstract] [Full Text] [PDF]

Anna Csiszar, Nazar Labinskyy, Andrej Podlutsky, Pawel M. Kaminski, Michael S. Wolin, Cuihua Zhang, Partha Mukhopadhyay, Pal Pacher, Furong Hu, Rafael de Cabo, Praveen Ballabh, and Zoltan Ungvari: Vasoprotective effects of resveratrol and SIRT1: attenuation of cigarette smoke-induced oxidative stress and proinflammatory phenotypic alterations
Am J Physiol Heart Circ Physiol 294: H2721-H2735, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00235.2008 [Abstract] [Full Text] [PDF]

Philippe Morimont, Bernard Lambermont, Alexandre Ghuysen, Paul Gerard, Philippe Kolh, Patrizio Lancellotti, Vincent Tchana-Sato, Thomas Desaive, and Vincent D'Orio: Effective arterial elastance as an index of pulmonary vascular load
Am J Physiol Heart Circ Physiol 294: H2736-H2742, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00796.2007 [Abstract] [Full Text] [PDF]

Kamakshi Sachidanandam, Mostafa M. Elgebaly, Alex K. Harris, Jim R. Hutchinson, Erin M. Mezzetti, Vera Portik-Dobos, and Adviye Ergul: Effect of chronic and selective endothelin receptor antagonism on microvascular function in Type 2 diabetes
Am J Physiol Heart Circ Physiol 294: H2743-H2749, 2008. First published April 18, 2008; doi:10.1152/ajpheart.91487.2007 [Abstract] [Full Text] [PDF]

Wei Zhang and Sándor J. Kovács: The diastatic pressure-volume relationship is not the same as the end-diastolic pressure-volume relationship
Am J Physiol Heart Circ Physiol 294: H2750-H2760, 2008. First published April 18, 2008; doi:10.1152/ajpheart.00200.2008 [Abstract] [Full Text] [PDF]

Zhen Li, Changqing Yu, Yu Han, Hongmei Ren, Weibin Shi, Chunjiang Fu, Duofen He, Lan Huang, Chengming Yang, Xukai Wang, Lin Zhou, Laureano D. Asico, Chunyu Zeng, and Pedro A. Jose: Inhibitory effect of D₁-like and D₃ dopamine receptors on norepinephrine-induced proliferation in vascular smooth muscle cells
Am J Physiol Heart Circ Physiol 294: H2761-H2768, 2008. First published April 25, 2008; doi:10.1152/ajpheart.01344.2007 [Abstract] [Full Text] [PDF]

Farisa Syeda, Elizabeth Tullis, Arthur S. Slutsky, and Haibo Zhang: Human neutrophil peptides upregulate expression of COX-2 and endothelin-1 by inducing oxidative stress
Am J Physiol Heart Circ Physiol 294: H2769-H2774, 2008. First published April 25, 2008; doi:10.1152/ajpheart.00211.2008 [Abstract] [Full Text] [PDF]

Peter J. Leary, Surender Rajasekaran, R. Ray Morrison, Elaine I. Tuomanen, Thomas K. Chin, and Polly A. Hofmann: A cardioprotective role for platelet-activating factor through NOS-dependent S-nitrosylation
Am J Physiol Heart Circ Physiol 294: H2775-H2784, 2008. First published April 25, 2008; doi:10.1152/ajpheart.00269.2008 [Abstract] [Full Text] [PDF]

Takaaki Fujii, Mitsuho Onimaru, Yoshikazu Yonemitsu, Hiroyuki Kuwano, and Katsuo Sueishi: Statins restore ischemic limb blood flow in diabetic microangiopathy via eNOS/NO upregulation but not via PDGF-BB expression
Am J Physiol Heart Circ Physiol 294: H2785-H2791, 2008. First published April 25, 2008; doi:10.1152/ajpheart.00149.2008 [Abstract] [Full Text] [PDF]

Erik R. Kline, Dean J. Kleinhenz, Bill Liang, Sergey Dikalov, David M. Guidot, C. Michael Hart, Dean P. Jones, and Roy L. Sutliff: Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration
Am J Physiol Heart Circ Physiol 294: H2792-H2804, 2008. First published May 2, 2008; doi:10.1152/ajpheart.91447.2007 [Abstract] [Full Text] [PDF]

Ning Zou, Lihua Ao, Joseph C. Cleveland, Jr., Xiaoping Yang, Xin Su, Guang-Yun Cai, Anirban Banerjee, David A. Fullerton, and Xianzhong Meng: Critical role of extracellular heat shock cognate protein 70 in the myocardial inflammatory response and cardiac dysfunction after global ischemia-reperfusion
Am J Physiol Heart Circ Physiol 294: H2805-H2813, 2008. First published April 25, 2008; doi:10.1152/ajpheart.00299.2008 [Abstract] [Full Text] [PDF]

Micheline M. de Resende and Andrew S. Greene: Effect of ANG II on endothelial cell apoptosis and survival and its impact on skeletal muscle angiogenesis after electrical stimulation
Am J Physiol Heart Circ Physiol 294: H2814-H2821, 2008. First published April 25, 2008; doi:10.1152/ajpheart.00095.2008 [Abstract] [Full Text] [PDF]

Cédric Filipe, Lætitia Lam Shang Leen, Laurent Brouchet, Audrey Billon, Vincent Benouaich, Vincent Fontaine, Pierre Gourdy, Françoise Lenfant, Jean-François Arnal, Alain-Pierre Gadeau, and Henrik Laurell: Estradiol accelerates endothelial healing through the retrograde commitment of uninjured endothelium
Am J Physiol Heart Circ Physiol 294: H2822-H2830, 2008. First published April 25, 2008; doi:10.1152/ajpheart.00129.2008 [Abstract] [Full Text] [PDF]

Chiara Foglieni, Francesco Maisano, Lorella Dreas, Alessio Giazzon, Giacomo Ruotolo, Elisabetta Ferrero, Laura Li Volsi, Stefano Coli, Gianfranco Sinagra, Bartolo Zingone, Ottavio Alfieri, Anton E. Becker, and Attilio Maseri: Mild inflammatory activation of mammary arteries in patients with acute coronary syndromes
Am J Physiol Heart Circ Physiol 294: H2831-H2837, 2008. First published April 25, 2008; doi:10.1152/ajpheart.91428.2007 [Abstract] [Full Text] [PDF]

Garrett J. Gross, Kathryn M. Gauthier, Jeannine Moore, John R. Falck, Bruce D. Hammock, William B. Campbell, and Kasem Nithipatikom: Effects of the selective EET antagonist, 14,15-EEZE, on cardioprotection produced by exogenous or endogenous EETs in the canine heart
Am J Physiol Heart Circ Physiol 294: H2838-H2844, 2008. First published April 25, 2008; doi:10.1152/ajpheart.00186.2008 [Abstract] [Full Text] [PDF]

Yuan Li, Magda Descorbeth, and Madhu B. Anand-Srivastava: Role of oxidative stress in high glucose-induced decreased expression of G_i ${alpha}$ proteins and adenylyl cyclase signaling in vascular smooth muscle cells
Am J Physiol Heart Circ Physiol 294: H2845-H2854, 2008. First published April 25, 2008; doi:10.1152/ajpheart.91422.2007 [Abstract] [Full Text] [PDF]

Víctor M. Blanco, Javier E. Stern, and Jessica A. Filosa: Tone-dependent vascular responses to astrocyte-derived signals
Am J Physiol Heart Circ Physiol 294: H2855-H2863, 2008. First published May 2, 2008; doi:10.1152/ajpheart.91451.2007 [Abstract] [Full Text] [PDF] [Supplemental Videos]

Mark A. Christman, II, Douglas J. Goetz, Eric Dickerson, Kelly D. McCall, Christopher J. Lewis, Fabian Benencia, Mitchell J. Silver, Leonard D. Kohn, and Ramiro Malgor: Wnt5a is expressed in murine and human atherosclerotic lesions
Am J Physiol Heart Circ Physiol 294: H2864-H2870, 2008. First published May 2, 2008; doi:10.1152/ajpheart.00982.2007 [Abstract] [Full Text] [PDF]

Ryo Takeda, Etsu Suzuki, Masao Takahashi, Shigeyoshi Oba, Hiroaki Nishimatsu, Kenjiro Kimura, Tetsuo Nagano, Ryozo Nagai, and Yasunobu Hirata: Calcineurin is critical for sodium-induced neointimal formation in normotensive and hypertensive rats
Am J Physiol Heart Circ Physiol 294: H2871-H2878, 2008. First published May 2, 2008; doi:10.1152/ajpheart.00031.2008 [Abstract] [Full Text] [PDF]

Masao Takahashi, Etsu Suzuki, Ryo Takeda, Shigeyoshi Oba, Hiroaki Nishimatsu, Kenjiro Kimura, Tetsuo Nagano, Ryozo Nagai, and Yasunobu Hirata: Angiotensin II and tumor necrosis factor- ${alpha}$ synergistically promote monocyte chemoattractant protein-1 expression: roles of NF- ${kappa}$ B, p38, and reactive oxygen species
Am J Physiol Heart Circ Physiol 294: H2879-H2888, 2008. First published April 25, 2008; doi:10.1152/ajpheart.91406.2007 [Abstract] [Full Text] [PDF]

Qianwen Wang, Rajakumar V. Donthi, Jianxun Wang, Alex J. Lange, Lewis J. Watson, Steven P. Jones, and Paul N. Epstein: Cardiac phosphatase-deficient 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase increases glycolysis, hypertrophy, and myocyte resistance to hypoxia
Am J Physiol Heart Circ Physiol 294: H2889-H2897, 2008. First published May 2, 2008; doi:10.1152/ajpheart.91501.2007 [Abstract] [Full Text] [PDF]

INNOVATIVE METHODOLOGY:

Brant E. Isakson, Angela K. Best, and Brian R. Duling: Incidence of protein on actin bridges between endothelium and smooth muscle in arterioles demonstrates heterogeneous connexin expression and phosphorylation
Am J Physiol Heart Circ Physiol 294: H2898-H2904, 2008. First published April 11, 2008; doi:10.1152/ajpheart.91488.2007 [Abstract] [Full Text] [PDF] [Supplemental Figures]

Aleksander S. Golub and Roland N. Pittman: PO₂ measurements in the microcirculation using phosphorescence quenching microscopy at high magnification
Am J Physiol Heart Circ Physiol 294: H2905-H2916, 2008. First published March 28, 2008; doi:10.1152/ajpheart.01347.2007 [Abstract] [Full Text] [PDF]

CORRIGENDA:

: Corrigendum
Am J Physiol Heart Circ Physiol 294: H2917-H2917, 2008; doi:10.1152/ajpheart.zh4-8340-corr.2008 [Full Text] [PDF]

Cover Caption:

Cover

Cover: Rotigaptide prevents ischemia-induced dephosphorylation of connexin43 in cardiac gap junctions. Confocal immunofluorescence images show no change in the distribution, pattern, or quantity of Cx43 signal in rotigaptide-treated hearts during ischemia. See Kjølbye AL, Dikshteyn M, Eloff BC, Deschênes I, Rosenbaum DS. Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans. Am J Physiol Heart Circ Physiol 294: H41–H49, 2008.