AJP - Heart and Circulatory Physiology -- Table of Contents (August 1 2008, 295 [2])

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REVIEW:

Nosratola D. Vaziri: Mechanisms of lead-induced hypertension and cardiovascular disease
Am J Physiol Heart Circ Physiol 295: H454-H465, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00158.2008 [Abstract] [Full Text] [PDF]

Arnaldo Lopez-Ruiz, Julio Sartori-Valinotti, Licy L. Yanes, Radu Iliescu, and Jane F. Reckelhoff: Sex differences in control of blood pressure: role of oxidative stress in hypertension in females
Am J Physiol Heart Circ Physiol 295: H466-H474, 2008. First published June 20, 2008; doi:10.1152/ajpheart.01232.2007 [Abstract] [Full Text] [PDF]

EDITORIAL FOCUS:

Anna Csiszar and Zoltan Ungvari: Endothelial dysfunction and vascular inflammation in Type 2 diabetes: interaction of AGE/RAGE and TNF- ${alpha}$ signaling
Am J Physiol Heart Circ Physiol 295: H475-H476, 2008. First published July 3, 2008; doi:10.1152/ajpheart.00644.2008 [Full Text] [PDF]

Jon O. Lundberg and Eddie Weitzberg: Nitrite reduction to nitric oxide in the vasculature
Am J Physiol Heart Circ Physiol 295: H477-H478, 2008. First published June 27, 2008; doi:10.1152/ajpheart.00611.2008 [Full Text] [PDF]

Hemal H. Patel and Rennolds S. Ostrom: An orphan GPCR finds a home in the heart
Am J Physiol Heart Circ Physiol 295: H479-H481, 2008. First published June 27, 2008; doi:10.1152/ajpheart.00633.2008 [Full Text] [PDF]

TRANSLATIONAL PHYSIOLOGY:

Christina Kolyva, Jos A. E. Spaan, Jan J. Piek, and Maria Siebes: Windkesselness of coronary arteries hampers assessment of human coronary wave speed by single-point technique
Am J Physiol Heart Circ Physiol 295: H482-H490, 2008. First published May 30, 2008; doi:10.1152/ajpheart.00223.2008 [Abstract] [Full Text] [PDF]

Xue Gao, Hanrui Zhang, Ann Marie Schmidt, and Cuihua Zhang: AGE/RAGE produces endothelial dysfunction in coronary arterioles in Type 2 diabetic mice
Am J Physiol Heart Circ Physiol 295: H491-H498, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00464.2008 [Abstract] [Full Text] [PDF]

ARTICLES:

Wael F. Alzawahra, M. A. Hassan Talukder, Xiaoping Liu, Alexandre Samouilov, and Jay L. Zweier: Heme proteins mediate the conversion of nitrite to nitric oxide in the vascular wall
Am J Physiol Heart Circ Physiol 295: H499-H508, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00374.2008 [Abstract] [Full Text] [PDF]

John W. Adams, Jianming Wang, James R. Davis, Chen Liaw, Ibragim Gaidarov, Joel Gatlin, Nancy D. Dalton, Yusu Gu, John Ross, Jr., Dominic Behan, Ken Chien, and Daniel Connolly: Myocardial expression, signaling, and function of GPR22: a protective role for an orphan G protein-coupled receptor
Am J Physiol Heart Circ Physiol 295: H509-H521, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00368.2008 [Abstract] [Full Text] [PDF]

Marcus Carlsson, Nael F. Osman, Philip C. Ursell, Alastair J. Martin, and Maythem Saeed: Quantitative MR measurements of regional and global left ventricular function and strain after intramyocardial transfer of VM202 into infarcted swine myocardium
Am J Physiol Heart Circ Physiol 295: H522-H532, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00280.2008 [Abstract] [Full Text] [PDF]

Carolyn A. Carr, Daniel J. Stuckey, Louise Tatton, Damian J. Tyler, Sarah J. M. Hale, Dominic Sweeney, Jürgen E. Schneider, Enca Martin-Rendon, George K. Radda, Sian E. Harding, Suzanne M. Watt, and Kieran Clarke: Bone marrow-derived stromal cells home to and remain in the infarcted rat heart but fail to improve function: an in vivo cine-MRI study
Am J Physiol Heart Circ Physiol 295: H533-H542, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00094.2008 [Abstract] [Full Text] [PDF] [Supplemental Material]

Viswanathan Rajagopalan, Irving H. Zucker, Jocelyn A. Jones, Michaela Carlson, and Ying J. Ma: Cardiac ErbB-1/ErbB-2 mutant expression in young adult mice leads to cardiac dysfunction
Am J Physiol Heart Circ Physiol 295: H543-H554, 2008. First published July 3, 2008; doi:10.1152/ajpheart.91436.2007 [Abstract] [Full Text] [PDF]

Øyvind Sverre Svendsen, Åsa Lidén, Torbjørn Nedrebø, Kristofer Rubin, and Rolf K. Reed: Integrin ${alpha}$ _vβ₃ acts downstream of insulin in normalization of interstitial fluid pressure in sepsis and in cell-mediated collagen gel contraction
Am J Physiol Heart Circ Physiol 295: H555-H560, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00161.2008 [Abstract] [Full Text] [PDF]

Hongguang Wei and Richard S. Vander Heide: Heat stress activates AKT via focal adhesion kinase-mediated pathway in neonatal rat ventricular myocytes
Am J Physiol Heart Circ Physiol 295: H561-H568, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00401.2008 [Abstract] [Full Text] [PDF]

Anna Csiszar, Nazar Labinskyy, Hanjoong Jo, Praveen Ballabh, and Zoltan Ungvari: Differential proinflammatory and prooxidant effects of bone morphogenetic protein-4 in coronary and pulmonary arterial endothelial cells
Am J Physiol Heart Circ Physiol 295: H569-H577, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00180.2008 [Abstract] [Full Text] [PDF]

Yan Bai, Kin L. Siu, Salman Ashraf, Luca Faes, Giandomenico Nollo, and Ki H. Chon: Nonlinear coupling is absent in acute myocardial patients but not healthy subjects
Am J Physiol Heart Circ Physiol 295: H578-H586, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00247.2008 [Abstract] [Full Text] [PDF]

Michael J. Davis, Megan M. Lane, Ann M. Davis, David Durtschi, David C. Zawieja, Mariappan Muthuchamy, and Anatoliy A. Gashev: Modulation of lymphatic muscle contractility by the neuropeptide substance P
Am J Physiol Heart Circ Physiol 295: H587-H597, 2008. First published June 6, 2008; doi:10.1152/ajpheart.01029.2007 [Abstract] [Full Text] [PDF]

T. Tao, S. C. O'Neill, M. E. Diaz, Y. T. Li, D. A. Eisner, and H. Zhang: Alternans of cardiac calcium cycling in a cluster of ryanodine receptors: a simulation study
Am J Physiol Heart Circ Physiol 295: H598-H609, 2008. First published May 30, 2008; doi:10.1152/ajpheart.01086.2007 [Abstract] [Full Text] [PDF]

Hiroshi Ashikaga, Benjamin A. Coppola, Katrina G. Yamazaki, Francisco J. Villarreal, Jeffrey H. Omens, and James W. Covell: Changes in regional myocardial volume during the cardiac cycle: implications for transmural blood flow and cardiac structure
Am J Physiol Heart Circ Physiol 295: H610-H618, 2008. First published May 30, 2008; doi:10.1152/ajpheart.00107.2008 [Abstract] [Full Text] [PDF]

Xiaoguang Liu, Chunyuan Li, John R. Falck, Richard J. Roman, David R. Harder, and Raymond C. Koehler: Interaction of nitric oxide, 20-HETE, and EETs during functional hyperemia in whisker barrel cortex
Am J Physiol Heart Circ Physiol 295: H619-H631, 2008. First published May 23, 2008; doi:10.1152/ajpheart.01211.2007 [Abstract] [Full Text] [PDF] [Supplemental Tables]

Chao-Yin Chen, Drin Chow, Nipavan Chiamvimonvat, Kathryn A. Glatter, Ning Li, Yuxia He, Kent E. Pinkerton, and Ann C. Bonham: Short-term secondhand smoke exposure decreases heart rate variability and increases arrhythmia susceptibility in mice
Am J Physiol Heart Circ Physiol 295: H632-H639, 2008. First published June 13, 2008; doi:10.1152/ajpheart.91535.2007 [Abstract] [Full Text] [PDF]

Borut Kirn, Annemieke Jansen, Frank Bracke, Berry van Gelder, Theo Arts, and Frits W. Prinzen: Mechanical discoordination rather than dyssynchrony predicts reverse remodeling upon cardiac resynchronization
Am J Physiol Heart Circ Physiol 295: H640-H646, 2008. First published May 30, 2008; doi:10.1152/ajpheart.00106.2008 [Abstract] [Full Text] [PDF]

Chao Yuan, Quanhu Sheng, Haixu Tang, Yixue Li, Rong Zeng, and R. John Solaro: Quantitative comparison of sarcomeric phosphoproteomes of neonatal and adult rat hearts
Am J Physiol Heart Circ Physiol 295: H647-H656, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00357.2008 [Abstract] [Full Text] [PDF]

Ayanna S. Augustus, Jonathan Buchanan, Sankar Addya, Giuseppe Rengo, Richard G. Pestell, Paolo Fortina, Walter J. Koch, Andre Bensadoun, E. Dale Abel, and Michael P. Lisanti: Substrate uptake and metabolism are preserved in hypertrophic caveolin-3 knockout hearts
Am J Physiol Heart Circ Physiol 295: H657-H666, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00387.2008 [Abstract] [Full Text] [PDF] [Supplemental Table]

Victor A. Maltsev, John W. Kyle, Sudhish Mishra, and Abertas Undrovinas: Molecular identity of the late sodium current in adult dog cardiomyocytes identified by Na_v1.5 antisense inhibition
Am J Physiol Heart Circ Physiol 295: H667-H676, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00111.2008 [Abstract] [Full Text] [PDF]

Yanli Song, Laura Coleman, Jianru Shi, Hideyuki Beppu, Kaori Sato, Kenneth Walsh, Joseph Loscalzo, and Ying-Yi Zhang: Inflammation, endothelial injury, and persistent pulmonary hypertension in heterozygous BMPR2-mutant mice
Am J Physiol Heart Circ Physiol 295: H677-H690, 2008. First published June 13, 2008; doi:10.1152/ajpheart.91519.2007 [Abstract] [Full Text] [PDF]

Alex Y. Tan, Shengmei Zhou, Byung Chun Jung, Masahiro Ogawa, Lan S. Chen, Michael C. Fishbein, and Peng-Sheng Chen: Ectopic atrial arrhythmias arising from canine thoracic veins during in vivo stellate ganglia stimulation
Am J Physiol Heart Circ Physiol 295: H691-H698, 2008. First published June 6, 2008; doi:10.1152/ajpheart.01321.2007 [Abstract] [Full Text] [PDF]

Yuan Huang, Casey D. Wright, Satoru Kobayashi, Chastity L. Healy, Megan Elgethun, Andrew Cypher, Qiangrong Liang, and Timothy D. O'Connell: GATA4 is a survival factor in adult cardiac myocytes but is not required for ${alpha}$ 1A-adrenergic receptor survival signaling
Am J Physiol Heart Circ Physiol 295: H699-H707, 2008. First published June 13, 2008; doi:10.1152/ajpheart.01204.2007 [Abstract] [Full Text] [PDF]

Zhong-Fang Lai, Yu-Zhen Chen, Li-Ping Feng, Xian-Min Meng, Jin-Feng Ding, Lai-Yuan Wang, Jue Ye, Ping Li, Xiao-Shu Cheng, Yasunori Kitamoto, Koshiro Monzen, Issei Komuro, Nobuo Sakaguchi, and Shokei Kim-Mitsuyama: Overexpression of TNNI3K, a cardiac-specific MAP kinase, promotes P19CL6-derived cardiac myogenesis and prevents myocardial infarction-induced injury
Am J Physiol Heart Circ Physiol 295: H708-H716, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00252.2008 [Abstract] [Full Text] [PDF]

Jacques Ohayon, Gérard Finet, Ahmed M. Gharib, Daniel A. Herzka, Philippe Tracqui, Julie Heroux, Gilles Rioufol, Melanie S. Kotys, Abdalla Elagha, and Roderic I. Pettigrew: Necrotic core thickness and positive arterial remodeling index: emergent biomechanical factors for evaluating the risk of plaque rupture
Am J Physiol Heart Circ Physiol 295: H717-H727, 2008. First published June 27, 2008; doi:10.1152/ajpheart.00005.2008 [Abstract] [Full Text] [PDF]

Beihua Zhong and Donna H. Wang: N-oleoyldopamine, a novel endogenous capsaicin-like lipid, protects the heart against ischemia-reperfusion injury via activation of TRPV1
Am J Physiol Heart Circ Physiol 295: H728-H735, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00022.2008 [Abstract] [Full Text] [PDF]

Eleni Metaxa, Hui Meng, Shashikanth R. Kaluvala, Michael P. Szymanski, Rocco A. Paluch, and John Kolega: Nitric oxide-dependent stimulation of endothelial cell proliferation by sustained high flow
Am J Physiol Heart Circ Physiol 295: H736-H742, 2008. First published June 13, 2008; doi:10.1152/ajpheart.01156.2007 [Abstract] [Full Text] [PDF]

Peter C. Minneci, Katherine J. Deans, Sruti Shiva, Huang Zhi, Steven M. Banks, Steven Kern, Charles Natanson, Steven B. Solomon, and Mark T. Gladwin: Nitrite reductase activity of hemoglobin as a systemic nitric oxide generator mechanism to detoxify plasma hemoglobin produced during hemolysis
Am J Physiol Heart Circ Physiol 295: H743-H754, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00151.2008 [Abstract] [Full Text] [PDF]

Maaike G. J. Gademan, Rutger J. van Bommel, Claudia Ypenburg, Joris C. W. Haest, Martin J. Schalij, Ernst E. van der Wall, Jeroen J. Bax, and Cees A. Swenne: Biventricular pacing in chronic heart failure acutely facilitates the arterial baroreflex
Am J Physiol Heart Circ Physiol 295: H755-H760, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00170.2008 [Abstract] [Full Text] [PDF]

Katrina Go Yamazaki, Diego Romero-Perez, Maraliz Barraza-Hidalgo, Michelle Cruz, Maria Rivas, Brenda Cortez-Gomez, Guillermo Ceballos, and Francisco Villarreal: Short- and long-term effects of (–)-epicatechin on myocardial ischemia-reperfusion injury
Am J Physiol Heart Circ Physiol 295: H761-H767, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00413.2008 [Abstract] [Full Text] [PDF]

J. Darcy O'Brien and Susan E. Howlett: Simulated ischemia-induced preconditioning of isolated ventricular myocytes from young adult and aged Fischer-344 rat hearts
Am J Physiol Heart Circ Physiol 295: H768-H777, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00432.2008 [Abstract] [Full Text] [PDF]

Geoffrey S. Gilmartin, Renaud Tamisier, Matthew Curley, and J. Woodrow Weiss: Ventilatory, hemodynamic, sympathetic nervous system, and vascular reactivity changes after recurrent nocturnal sustained hypoxia in humans
Am J Physiol Heart Circ Physiol 295: H778-H785, 2008. First published June 6, 2008; doi:10.1152/ajpheart.00653.2007 [Abstract] [Full Text] [PDF]

Madelyn S. Hanson, Alan H. Stephenson, Elizabeth A. Bowles, Meera Sridharan, Shaquria Adderley, and Randy S. Sprague: Phosphodiesterase 3 is present in rabbit and human erythrocytes and its inhibition potentiates iloprost-induced increases in cAMP
Am J Physiol Heart Circ Physiol 295: H786-H793, 2008. First published June 27, 2008; doi:10.1152/ajpheart.00349.2008 [Abstract] [Full Text] [PDF]

Wei Zheng, Lance P. Christensen, and Robert J. Tomanek: Differential effects of cyclic and static stretch on coronary microvascular endothelial cell receptors and vasculogenic/angiogenic responses
Am J Physiol Heart Circ Physiol 295: H794-H800, 2008. First published June 27, 2008; doi:10.1152/ajpheart.00343.2008 [Abstract] [Full Text] [PDF]

Saurabh Jha, John W. Calvert, Mark R. Duranski, Arun Ramachandran, and David J. Lefer: Hydrogen sulfide attenuates hepatic ischemia-reperfusion injury: role of antioxidant and antiapoptotic signaling
Am J Physiol Heart Circ Physiol 295: H801-H806, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00377.2008 [Abstract] [Full Text] [PDF]

De-Pei Li, Qing Yang, Hao-Min Pan, and Hui-Lin Pan: Plasticity of pre- and postsynaptic GABA_B receptor function in the paraventricular nucleus in spontaneously hypertensive rats
Am J Physiol Heart Circ Physiol 295: H807-H815, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00259.2008 [Abstract] [Full Text] [PDF]

Sanjana Dayal, Roman N. Rodionov, Erland Arning, Teodoro Bottiglieri, Masumi Kimoto, Daryl J. Murry, John P. Cooke, Frank M. Faraci, and Steven R. Lentz: Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia
Am J Physiol Heart Circ Physiol 295: H816-H825, 2008. First published June 20, 2008; doi:10.1152/ajpheart.01348.2007 [Abstract] [Full Text] [PDF]

Christopher J. Clarke, Simon Forman, James Pritchett, Vasken Ohanian, and Jacqueline Ohanian: Phospholipase C- ${delta}$ ₁ modulates sustained contraction of rat mesenteric small arteries in response to noradrenaline, but not endothelin-1
Am J Physiol Heart Circ Physiol 295: H826-H834, 2008. First published June 20, 2008; doi:10.1152/ajpheart.01396.2007 [Abstract] [Full Text] [PDF]

Zsolt Bagi, Nora Erdei, and Akos Koller: High intraluminal pressure via H₂O₂ upregulates arteriolar constrictions to angiotensin II by increasing the functional availability of AT1 receptors
Am J Physiol Heart Circ Physiol 295: H835-H841, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00205.2008 [Abstract] [Full Text] [PDF]

Pablo F. Soto, Pilar Herrero, Kenneth B. Schechtman, Alan D. Waggoner, Jeffrey M. Baumstark, Ali A. Ehsani, and Robert J. Gropler: Exercise training impacts the myocardial metabolism of older individuals in a gender-specific manner
Am J Physiol Heart Circ Physiol 295: H842-H850, 2008. First published June 20, 2008; doi:10.1152/ajpheart.91426.2007 [Abstract] [Full Text] [PDF]

Y. G. Wang, A. V. Zima, X. Ji, R. Pabbidi, L. A. Blatter, and S. L. Lipsius: Ginsenoside Re suppresses electromechanical alternans in cat and human cardiomyocytes
Am J Physiol Heart Circ Physiol 295: H851-H859, 2008. First published June 20, 2008; doi:10.1152/ajpheart.01242.2007 [Abstract] [Full Text] [PDF]

Samuel C. Lieber, Hongyu Qiu, Li Chen, You-Tang Shen, Chull Hong, William C. Hunter, Nadine Aubry, Stephen F. Vatner, and Dorothy E. Vatner: Cardiac dysfunction in aging conscious rats: altered cardiac cytoskeletal proteins as a potential mechanism
Am J Physiol Heart Circ Physiol 295: H860-H866, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00146.2008 [Abstract] [Full Text] [PDF]

M. Lindenberger, H. Olsen, and T. Länne: Lower capacitance response and capillary fluid absorption in women to defend central blood volume in response to acute hypovolemic circulatory stress
Am J Physiol Heart Circ Physiol 295: H867-H873, 2008. First published June 27, 2008; doi:10.1152/ajpheart.00332.2008 [Abstract] [Full Text] [PDF]

Alexandre D. T. Costa and Keith D. Garlid: Intramitochondrial signaling: interactions among mitoK_ATP, PKC ${varepsilon}$ , ROS, and MPT
Am J Physiol Heart Circ Physiol 295: H874-H882, 2008. First published June 27, 2008; doi:10.1152/ajpheart.01189.2007 [Abstract] [Full Text] [PDF]

Derek J. Dosdall, Paul B. Tabereaux, Jong J. Kim, Gregory P. Walcott, Jack M. Rogers, Cheryl R. Killingsworth, Jian Huang, Peter G. Robertson, William M. Smith, and Raymond E. Ideker: Chemical ablation of the Purkinje system causes early termination and activation rate slowing of long-duration ventricular fibrillation in dogs
Am J Physiol Heart Circ Physiol 295: H883-H889, 2008. First published June 27, 2008; doi:10.1152/ajpheart.00466.2008 [Abstract] [Full Text] [PDF]

Karni S. Moshal, Srinivas M. Tipparaju, Thomas P. Vacek, Munish Kumar, Mahavir Singh, Iluiana E. Frank, Phani K. Patibandla, Neetu Tyagi, Jayesh Rai, Naira Metreveli, Walter E. Rodriguez, Michael T. Tseng, and Suresh C. Tyagi: Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia
Am J Physiol Heart Circ Physiol 295: H890-H897, 2008. First published June 20, 2008; doi:10.1152/ajpheart.00099.2008 [Abstract] [Full Text] [PDF]

INNOVATIVE METHODOLOGY:

Yanyan Jiang, Ke Wen, Xueping Zhou, Diane Schwegler-Berry, Vince Castranova, and Pingnian He: Three-dimensional localization and quantification of PAF-induced gap formation in intact venular microvessels
Am J Physiol Heart Circ Physiol 295: H898-H906, 2008. First published May 30, 2008; doi:10.1152/ajpheart.00309.2008 [Abstract] [Full Text] [PDF] [Supplemental Video]

REPORTS:

Dinender K. Singla, Reetu D. Singla, and Debbie E. McDonald: Factors released from embryonic stem cells inhibit apoptosis in H9c2 cells through PI3K/Akt but not ERK pathway
Am J Physiol Heart Circ Physiol 295: H907-H913, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00279.2008 [Abstract] [Full Text] [PDF]

PERSPECTIVE:

Richard N. Re and Julia L. Cook: The physiological basis of intracrine stem cell regulation
Am J Physiol Heart Circ Physiol 295: H447-H453, 2008. First published June 13, 2008; doi:10.1152/ajpheart.00461.2008 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Masson's trichrome of the normal external jugular vein shows that the normal extracellular matrix (blue color) is located within the media and adventitia. See Misra S, Fu AA, Puggioni A, Karimi KM, Mandrekar JN, Glockner JF, Juncos LA, Anwer B, McGuire AM, Mukhopadhyay D. Increased shear stress with upregulation of VEGF-A and its receptors and MMP-2, MMP-9, and TIMP-1 in venous stenosis of hemodialysis grafts. Am J Physiol Heart Circ Physiol 294: H2219–H2230, 2008.