REVIEW:

Jason N. Peart and John P. Headrick

Clinical cardioprotection and the value of conditioning responses
Am J Physiol Heart Circ Physiol 296: H1705-H1720, 2009. First published April 10, 2009; doi:10.1152/ajpheart.00162.2009 [Abstract] [Full Text] [PDF]  

EDITORIAL FOCUS:

Massimo Pagani and Daniela Lucini

Can autonomic monitoring predict results in distance runners?
Am J Physiol Heart Circ Physiol 296: H1721-H1722, 2009. First published April 17, 2009; doi:10.1152/ajpheart.00337.2009 [Full Text] [PDF]  

Jayan Nagendran and Evangelos D. Michelakis

Mitochondrial NOS is upregulated in the hypoxic heart: implications for the function of the hypertrophied right ventricle
Am J Physiol Heart Circ Physiol 296: H1723-H1726, 2009. First published May 1, 2009; doi:10.1152/ajpheart.00380.2009 [Full Text] [PDF]  

TRANSLATIONAL PHYSIOLOGY:

Min Pu, Zhaohui Gao, Xueqian Zhang, Duanping Liao, Daniel K. Pu, Timothy Brennan, and William R. Davidson, Jr.

Impact of mitral regurgitation on left ventricular anatomic and molecular remodeling and systolic function: implication for outcome
Am J Physiol Heart Circ Physiol 296: H1727-H1732, 2009. First published March 27, 2009; doi:10.1152/ajpheart.00882.2008 [Abstract] [Full Text] [PDF]  

ARTICLES:

Vincenzo Manzi, Carlo Castagna, Elvira Padua, Mauro Lombardo, Stefano D'Ottavio, Michele Massaro, Maurizio Volterrani, and Ferdinando Iellamo

Dose-response relationship of autonomic nervous system responses to individualized training impulse in marathon runners
Am J Physiol Heart Circ Physiol 296: H1733-H1740, 2009. First published March 27, 2009; doi:10.1152/ajpheart.00054.2009 [Abstract] [Full Text] [PDF]  

Tamara Zaobornyj, Laura B. Valdez, Darío E. Iglesias, Manuel Gasco, Gustavo F. Gonzales, and Alberto Boveris

Mitochondrial nitric oxide metabolism during rat heart adaptation to high altitude: effect of sildenafil, L-NAME, and L-arginine treatments
Am J Physiol Heart Circ Physiol 296: H1741-H1747, 2009. First published April 3, 2009; doi:10.1152/ajpheart.00422.2008 [Abstract] [Full Text] [PDF]  

Xiaoxiao Gu and Kristyn S. Masters

Role of the MAPK/ERK pathway in valvular interstitial cell calcification
Am J Physiol Heart Circ Physiol 296: H1748-H1757, 2009. First published April 10, 2009; doi:10.1152/ajpheart.00099.2009 [Abstract] [Full Text] [PDF]  

André Diedrich, Alberto Porta, Franca Barbic, Robert J. Brychta, Pietro Bonizzi, Laura Diedrich, Sergio Cerutti, David Robertson, and Raffaello Furlan

Lateralization of expression of neural sympathetic activity to the vessels and effects of carotid baroreceptor stimulation
Am J Physiol Heart Circ Physiol 296: H1758-H1765, 2009. First published April 10, 2009; doi:10.1152/ajpheart.01045.2008 [Abstract] [Full Text] [PDF]  

Akinobu Itoh, Gaurav Krishnamurthy, Julia C. Swanson, Daniel B. Ennis, Wolfgang Bothe, Ellen Kuhl, Matts Karlsson, Lauren R. Davis, D. Craig Miller, and Neil B. Ingels, Jr.

Active stiffening of mitral valve leaflets in the beating heart
Am J Physiol Heart Circ Physiol 296: H1766-H1773, 2009. First published April 10, 2009; doi:10.1152/ajpheart.00120.2009 [Abstract] [Full Text] [PDF]  

Eric E. Lloyd, Sean P. Marrelli, and Robert M. Bryan, Jr.

cGMP does not activate two-pore domain K⁺ channels in cerebrovascular smooth muscle
Am J Physiol Heart Circ Physiol 296: H1774-H1780, 2009. First published April 10, 2009; doi:10.1152/ajpheart.00082.2009 [Abstract] [Full Text] [PDF]  

Gonzalo Peluffo, Pablo Calcerrada, Lucia Piacenza, Nelson Pizzano, and Rafael Radi

Superoxide-mediated inactivation of nitric oxide and peroxynitrite formation by tobacco smoke in vascular endothelium: studies in cultured cells and smokers
Am J Physiol Heart Circ Physiol 296: H1781-H1792, 2009. First published April 10, 2009; doi:10.1152/ajpheart.00930.2008 [Abstract] [Full Text] [PDF]  

Shunsuke Takei, Hinako Ichikawa, Kohei Johkura, Akimi Mogi, Heesung No, Susumu Yoshie, Daihachiro Tomotsune, and Katsunori Sasaki

Bone morphogenetic protein-4 promotes induction of cardiomyocytes from human embryonic stem cells in serum-based embryoid body development
Am J Physiol Heart Circ Physiol 296: H1793-H1803, 2009. First published April 10, 2009; doi:10.1152/ajpheart.01288.2008 [Abstract] [Full Text] [PDF]  

Shinji Yasuno, Satoru Usami, Koichiro Kuwahara, Michio Nakanishi, Yuji Arai, Hideyuki Kinoshita, Yasuaki Nakagawa, Masataka Fujiwara, Masao Murakami, Kenji Ueshima, Masaki Harada, and Kazuwa Nakao

Endogenous cardiac natriuretic peptides protect the heart in a mouse model of dilated cardiomyopathy and sudden death
Am J Physiol Heart Circ Physiol 296: H1804-H1810, 2009. First published April 3, 2009; doi:10.1152/ajpheart.01033.2008 [Abstract] [Full Text] [PDF]  

Ryan Reed, Barry Potter, Erika Smith, Rashmi Jadhav, Patricia Villalta, Hanjoong Jo, and Petra Rocic

Redox-sensitive Akt and Src regulate coronary collateral growth in metabolic syndrome
Am J Physiol Heart Circ Physiol 296: H1811-H1821, 2009. First published April 17, 2009; doi:10.1152/ajpheart.00920.2008 [Abstract] [Full Text] [PDF]  

Ramesh Saeedi, Varun V. Saran, Sherry S. Y. Wu, Erika S. Kume, Kim Paulson, Annie P. K. Chan, Hannah L. Parsons, Richard B. Wambolt, Jason R. B. Dyck, Roger W. Brownsey, and Michael F. Allard

AMP-activated protein kinase influences metabolic remodeling in H9c2 cells hypertrophied by arginine vasopressin
Am J Physiol Heart Circ Physiol 296: H1822-H1832, 2009. First published April 17, 2009; doi:10.1152/ajpheart.00396.2008 [Abstract] [Full Text] [PDF]  

Arshani N. Wansapura, Valerie Lasko, Zijian Xie, Olga V. Fedorova, Alexei Y. Bagrov, Jerry B Lingrel, and John N. Lorenz

Marinobufagenin enhances cardiac contractility in mice with ouabain-sensitive ₁ Na⁺-K⁺-ATPase
Am J Physiol Heart Circ Physiol 296: H1833-H1839, 2009. First published April 17, 2009; doi:10.1152/ajpheart.00285.2009 [Abstract] [Full Text] [PDF]  

Katherine Chang, Daliao Xiao, Xiaohui Huang, Lawrence D. Longo, and Lubo Zhang

Chronic hypoxia increases pressure-dependent myogenic tone of the uterine artery in pregnant sheep: role of ERK/PKC pathway
Am J Physiol Heart Circ Physiol 296: H1840-H1849, 2009. First published April 17, 2009; doi:10.1152/ajpheart.00090.2009 [Abstract] [Full Text] [PDF]  

Jiyeon Yang, Yoonjung Park, Hanrui Zhang, Xiangbin Xu, Glen A. Laine, Kevin C. Dellsperger, and Cuihua Zhang

Feed-forward signaling of TNF- and NF-B via IKK-β pathway contributes to insulin resistance and coronary arteriolar dysfunction in type 2 diabetic mice
Am J Physiol Heart Circ Physiol 296: H1850-H1858, 2009. First published April 10, 2009; doi:10.1152/ajpheart.01199.2008 [Abstract] [Full Text] [PDF]  

Maria Arejian, Yuan Li, and Madhu B. Anand-Srivastava

Nitric oxide attenuates the expression of natriuretic peptide receptor C and associated adenylyl cyclase signaling in aortic vascular smooth muscle cells: role of MAPK
Am J Physiol Heart Circ Physiol 296: H1859-H1867, 2009. First published February 27, 2009; doi:10.1152/ajpheart.01108.2008 [Abstract] [Full Text] [PDF] [Corrigendum]  

Christopher D. Johnson, Donal Melanaphy, Andrew Purse, Susan A. Stokesberry, Paula Dickson, and Alexander V. Zholos

Transient receptor potential melastatin 8 channel involvement in the regulation of vascular tone
Am J Physiol Heart Circ Physiol 296: H1868-H1877, 2009. First published April 10, 2009; doi:10.1152/ajpheart.01112.2008 [Abstract] [Full Text] [PDF]  

Charles R. Rosenfeld, Xiao-tie Liu, and Kevin DeSpain

Pregnancy modifies the large conductance Ca²⁺-activated K⁺ channel and cGMP-dependent signaling pathway in uterine vascular smooth muscle
Am J Physiol Heart Circ Physiol 296: H1878-H1887, 2009; doi:10.1152/ajpheart.01185.2008 [Abstract] [Full Text] [PDF]  

Arsalan Shabbir, David Zisa, Gen Suzuki, and Techung Lee

Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a noninvasive therapeutic regimen
Am J Physiol Heart Circ Physiol 296: H1888-H1897, 2009. First published April 24, 2009; doi:10.1152/ajpheart.00186.2009 [Abstract] [Full Text] [PDF]  

Ian G. Aldous, Samuel P. Veres, Alireza Jahangir, and J. Michael Lee

Differences in collagen cross-linking between the four valves of the bovine heart: a possible role in adaptation to mechanical fatigue
Am J Physiol Heart Circ Physiol 296: H1898-H1906, 2009. First published March 27, 2009; doi:10.1152/ajpheart.01173.2008 [Abstract] [Full Text] [PDF]  

Shuqin Xing, Shirng-Wreng Tsaih, Rong Yuan, Karen L. Svenson, Linda M. Jorgenson, Milly So, Beverly J. Paigen, and Ron Korstanje

Genetic influence on electrocardiogram time intervals and heart rate in aging mice
Am J Physiol Heart Circ Physiol 296: H1907-H1913, 2009. First published April 24, 2009; doi:10.1152/ajpheart.00681.2008 [Abstract] [Full Text] [PDF]  

Mary L. Modrick, Sean P. Didion, Curt D. Sigmund, and Frank M. Faraci

Role of oxidative stress and AT₁ receptors in cerebral vascular dysfunction with aging
Am J Physiol Heart Circ Physiol 296: H1914-H1919, 2009. First published April 24, 2009; doi:10.1152/ajpheart.00300.2009 [Abstract] [Full Text] [PDF]  

Donald D. Lund, Yi Chu, Jordan D. Miller, and Donald D. Heistad

Protective effect of extracellular superoxide dismutase on endothelial function during aging
Am J Physiol Heart Circ Physiol 296: H1920-H1925, 2009. First published April 17, 2009; doi:10.1152/ajpheart.01342.2008 [Abstract] [Full Text] [PDF]  

Caitlin S. Thompson-Torgerson, Hunter C. Champion, Lakshmi Santhanam, Z. Leah Harris, and Artin A. Shoukas

Cyclohexanone contamination from extracorporeal circuits impairs cardiovascular function
Am J Physiol Heart Circ Physiol 296: H1926-H1932, 2009. First published May 1, 2009; doi:10.1152/ajpheart.00184.2009 [Abstract] [Full Text] [PDF]  

Subash C. Gupta, Kenneth D. Varian, Naresh C. Bal, Jessica L. Abraham, Muthu Periasamy, and Paul M. L. Janssen

Pulmonary artery banding alters the expression of Ca²⁺ transport proteins in the right atrium in rabbits
Am J Physiol Heart Circ Physiol 296: H1933-H1939, 2009. First published April 17, 2009; doi:10.1152/ajpheart.00026.2009 [Abstract] [Full Text] [PDF]  

Steven Droogmans, Bram Roosens, Bernard Cosyns, Céline Degaillier, Sophie Hernot, Caroline Weytjens, Christian Garbar, Vicky Caveliers, Miriam Pipeleers-Marichal, Philippe R. Franken, Tony Lahoutte, Danny Schoors, and Guy Van Camp

Cyproheptadine prevents pergolide-induced valvulopathy in rats: an echocardiographic and histopathological study
Am J Physiol Heart Circ Physiol 296: H1940-H1948, 2009. First published April 3, 2009; doi:10.1152/ajpheart.01177.2008 [Abstract] [Full Text] [PDF]  

Chih-Sen Kang, Chien-Chang Chen, Chih-Chan Lin, Nen-Chung Chang, and Tsung-Ming Lee

Effect of ATP-sensitive potassium channel agonists on sympathetic hyperinnervation in postinfarcted rat hearts
Am J Physiol Heart Circ Physiol 296: H1949-H1959, 2009. First published April 3, 2009; doi:10.1152/ajpheart.00903.2008 [Abstract] [Full Text] [PDF]  

Jacek Waniewski, Joanna Stachowska-Pietka, and Michael F. Flessner

Distributed modeling of osmotically driven fluid transport in peritoneal dialysis: theoretical and computational investigations
Am J Physiol Heart Circ Physiol 296: H1960-H1968, 2009. First published March 27, 2009; doi:10.1152/ajpheart.00121.2009 [Abstract] [Full Text] [PDF]  

Ufuk Olgac, Dimos Poulikakos, Stefan C. Saur, Hatem Alkadhi, and Vartan Kurtcuoglu

Patient-specific three-dimensional simulation of LDL accumulation in a human left coronary artery in its healthy and atherosclerotic states
Am J Physiol Heart Circ Physiol 296: H1969-H1982, 2009. First published March 27, 2009; doi:10.1152/ajpheart.01182.2008 [Abstract] [Full Text] [PDF]  

Deepa S. De Silva, Richard M. Wilson, Christoph Hutchinson, Peter C. Ip, Anthony G. Garcia, Steve Lancel, Masa Ito, David R. Pimentel, and Flora Sam

Fenofibrate inhibits aldosterone-induced apoptosis in adult rat ventricular myocytes via stress-activated kinase-dependent mechanisms
Am J Physiol Heart Circ Physiol 296: H1983-H1993, 2009. First published April 24, 2009; doi:10.1152/ajpheart.00002.2009 [Abstract] [Full Text] [PDF]  

Einsley Janowski, Regina Day, Alexander Kraev, John C. Roder, Lars Cleemann, and Martin Morad

β-Adrenergic regulation of a novel isoform of NCX: sequence and expression of shark heart NCX in human kidney cells
Am J Physiol Heart Circ Physiol 296: H1994-H2006, 2009. First published April 24, 2009; doi:10.1152/ajpheart.00038.2009 [Abstract] [Full Text] [PDF] [Supplemental Figures]  

Inês Falcão-Pires, Nádia Gonçalves, Tiago Henriques-Coelho, Daniel Moreira-Gonçalves, Roberto Roncon-Albuquerque, Jr., and Adelino F. Leite-Moreira

Apelin decreases myocardial injury and improves right ventricular function in monocrotaline-induced pulmonary hypertension
Am J Physiol Heart Circ Physiol 296: H2007-H2014, 2009. First published April 3, 2009; doi:10.1152/ajpheart.00089.2009 [Abstract] [Full Text] [PDF]  

Ranjeet M. Dongaonkar, Randolph H. Stewart, Glen A. Laine, Michael J. Davis, David C. Zawieja, and Christopher M. Quick

Venomotion modulates lymphatic pumping in the bat wing
Am J Physiol Heart Circ Physiol 296: H2015-H2021, 2009. First published March 27, 2009; doi:10.1152/ajpheart.00418.2008 [Abstract] [Full Text] [PDF]  

Takeshi Nakamura and Hreday N. Sapru

Cardiovascular responses to microinjections of urocortins into the NTS: role of inotropic glutamate receptors
Am J Physiol Heart Circ Physiol 296: H2022-H2029, 2009. First published April 24, 2009; doi:10.1152/ajpheart.00191.2009 [Abstract] [Full Text] [PDF]  

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