AJP - Heart and Circulatory Physiology -- Table of Contents (May 1 2008, 294 [5])

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CALL FOR PAPERS:

K. Bridget Brosnihan, Ping Li, Jorge P. Figueroa, Detlev Ganten, and Carlos M. Ferrario: Estrogen, nitric oxide, and hypertension differentially modulate agonist-induced contractile responses in female transgenic (mRen2)27 hypertensive rats
Am J Physiol Heart Circ Physiol 294: H1995-H2001, 2008. First published March 14, 2008; doi:10.1152/ajpheart.01193.2007 [Abstract] [Full Text] [PDF]

Karl H. Schuleri, Luciano C. Amado, Andrew J. Boyle, Marco Centola, Anastasios P. Saliaris, Matthew R. Gutman, Konstantinos E. Hatzistergos, Behzad N. Oskouei, Jeffrey M. Zimmet, Randell G. Young, Alan W. Heldman, Albert C. Lardo, and Joshua M. Hare: Early improvement in cardiac tissue perfusion due to mesenchymal stem cells
Am J Physiol Heart Circ Physiol 294: H2002-H2011, 2008. First published February 29, 2008; doi:10.1152/ajpheart.00762.2007 [Abstract] [Full Text] [PDF]

INVITED REVIEW:

An L. Moens, Christiaan J. Vrints, Marc J. Claeys, Jean-Pierre Timmermans, Hunter C. Champion, and David A. Kass: Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease
Am J Physiol Heart Circ Physiol 294: H1971-H1977, 2008. First published March 28, 2008; doi:10.1152/ajpheart.91503.2007 [Abstract] [Full Text] [PDF]

Minga M. Sellers and John N. Stallone: Sympathy for the devil: the role of thromboxane in the regulation of vascular tone and blood pressure
Am J Physiol Heart Circ Physiol 294: H1978-H1986, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01318.2007 [Abstract] [Full Text] [PDF]

EDITORIAL FOCUS:

Catherine M. Fuller and Dale J. Benos: Putting the brakes on vascular smooth muscle cell migration
Am J Physiol Heart Circ Physiol 294: H1987-H1988, 2008. First published March 28, 2008; doi:10.1152/ajpheart.00249.2008 [Full Text] [PDF]

Lee L. Eckhardt, Tom C. Teelin, and Craig T. January: Is ranolazine an antiarrhythmic drug?
Am J Physiol Heart Circ Physiol 294: H1989-H1991, 2008. First published March 28, 2008; doi:10.1152/ajpheart.00285.2008 [Full Text] [PDF]

Candido Cabo: Modulation of impulse propagation by fibroblasts
Am J Physiol Heart Circ Physiol 294: H1992-H1993, 2008. First published March 21, 2008; doi:10.1152/ajpheart.00268.2008 [Full Text] [PDF]

Kirkwood A. Pritchard, Jr.: Surfactant protein D: not just for the lung anymore
Am J Physiol Heart Circ Physiol 294: H1994-H1994, 2008. First published April 4, 2008; doi:10.1152/ajpheart.00278.2008 [Full Text] [PDF]

TRANSLATIONAL PHYSIOLOGY:

Hitesh K. Jindal, Eduardo J. Folco, Gong Xin Liu, and Gideon Koren: Posttranslational modification of voltage-dependent potassium channel Kv1.5: COOH-terminal palmitoylation modulates its biological properties
Am J Physiol Heart Circ Physiol 294: H2012-H2021, 2008. First published March 14, 2008; doi:10.1152/ajpheart.01374.2007 [Abstract] [Full Text] [PDF]

ARTICLES:

Samira C. Grifoni, Susan E. McKey, and Heather A. Drummond: Hsc70 regulates cell surface ASIC2 expression and vascular smooth muscle cell migration
Am J Physiol Heart Circ Physiol 294: H2022-H2030, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01271.2007 [Abstract] [Full Text] [PDF]

Yejia Song, John C. Shryock, and Luiz Belardinelli: An increase of late sodium current induces delayed afterdepolarizations and sustained triggered activity in atrial myocytes
Am J Physiol Heart Circ Physiol 294: H2031-H2039, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01357.2007 [Abstract] [Full Text] [PDF] [Supplemental Figure]

Vincent Jacquemet and Craig S. Henriquez: Loading effect of fibroblast-myocyte coupling on resting potential, impulse propagation, and repolarization: insights from a microstructure model
Am J Physiol Heart Circ Physiol 294: H2040-H2052, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01298.2007 [Abstract] [Full Text] [PDF]

Gary D. Snyder, Rebecca E. Oberley-Deegan, Kelli L. Goss, Sara A. Romig-Martin, Lynn L. Stoll, Jeanne M. Snyder, and Neal L. Weintraub: Surfactant protein D is expressed and modulates inflammatory responses in human coronary artery smooth muscle cells
Am J Physiol Heart Circ Physiol 294: H2053-H2059, 2008. First published March 21, 2008; doi:10.1152/ajpheart.91529.2007 [Abstract] [Full Text] [PDF]

Hong Hui Wang, Hideyuki Tanaka, Xiaoran Qin, Tiejun Zhao, Li-Hong Ye, Tuyoshi Okagaki, Takeshi Katayama, Akio Nakamura, Ryoki Ishikawa, Sean E. Thatcher, Gary L. Wright, and Kazuhiro Kohama: Blebbistatin inhibits the chemotaxis of vascular smooth muscle cells by disrupting the myosin II-actin interaction
Am J Physiol Heart Circ Physiol 294: H2060-H2068, 2008. First published February 22, 2008; doi:10.1152/ajpheart.00970.2007 [Abstract] [Full Text] [PDF]

Vincent J. de Beer, Oana Sorop, Daniël A. Pijnappels, Dick H. Dekkers, Frans Boomsma, Jos M. J. Lamers, Dirk J. Duncker, and Daphne Merkus: Integrative control of coronary resistance vessel tone by endothelin and angiotensin II is altered in swine with a recent myocardial infarction
Am J Physiol Heart Circ Physiol 294: H2069-H2077, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01163.2007 [Abstract] [Full Text] [PDF]

Kaliyamurthi Venkatachalam, Srinivas Mummidi, Dolores M. Cortez, Sumanth D. Prabhu, Anthony J. Valente, and Bysani Chandrasekar: Resveratrol inhibits high glucose-induced PI3K/Akt/ERK-dependent interleukin-17 expression in primary mouse cardiac fibroblasts
Am J Physiol Heart Circ Physiol 294: H2078-H2087, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01363.2007 [Abstract] [Full Text] [PDF]

Philippe Pasdois, Bertrand Beauvoit, Liliane Tariosse, Béatrice Vinassa, Simone Bonoron-Adèle, and Pierre Dos Santos: Effect of diazoxide on flavoprotein oxidation and reactive oxygen species generation during ischemia-reperfusion: a study on Langendorff-perfused rat hearts using optic fibers
Am J Physiol Heart Circ Physiol 294: H2088-H2097, 2008. First published February 22, 2008; doi:10.1152/ajpheart.01345.2007 [Abstract] [Full Text] [PDF]

Ozlem Yalcin, Pinar Ulker, Ugur Yavuzer, Herbert J. Meiselman, and Oguz K. Baskurt: Nitric oxide generation by endothelial cells exposed to shear stress in glass tubes perfused with red blood cell suspensions: role of aggregation
Am J Physiol Heart Circ Physiol 294: H2098-H2105, 2008; doi:10.1152/ajpheart.00015.2008 [Abstract] [Full Text] [PDF]

Tomas G. Neilan, Thanh-Thao Ton-Nu, Yoshiaki Kawase, Ryuichi Yoneyama, Kozo Hoshino, Federica del Monte, Roger J. Hajjar, Michael H. Picard, Robert A. Levine, and Judy Hung: Progressive nature of chronic mitral regurgitation and the role of tissue Doppler-derived indexes
Am J Physiol Heart Circ Physiol 294: H2106-H2111, 2008. First published March 7, 2008; doi:10.1152/ajpheart.01128.2007 [Abstract] [Full Text] [PDF]

Steven P. Downie, Sheila M. Raynor, David N. Firmin, Nigel B. Wood, Simon A. Thom, Alun D. Hughes, Kim H. Parker, John H. N. Wolfe, and X. Yun Xu: Effects of elastic compression stockings on wall shear stress in deep and superficial veins of the calf
Am J Physiol Heart Circ Physiol 294: H2112-H2120, 2008. First published March 7, 2008; doi:10.1152/ajpheart.01302.2007 [Abstract] [Full Text] [PDF]

Zoltan Ungvari, Nazar Labinskyy, Sachin Gupte, Praveen N. Chander, John G. Edwards, and Anna Csiszar: Dysregulation of mitochondrial biogenesis in vascular endothelial and smooth muscle cells of aged rats
Am J Physiol Heart Circ Physiol 294: H2121-H2128, 2008; doi:10.1152/ajpheart.00012.2008 [Abstract] [Full Text] [PDF]

Wen-Chau Wu, Jiongjiong Wang, John A. Detre, Felix W. Wehrli, Emile Mohler, 3rd, Sarah J. Ratcliffe, and Thomas F. Floyd: Hyperemic flow heterogeneity within the calf, foot, and forearm measured with continuous arterial spin labeling MRI
Am J Physiol Heart Circ Physiol 294: H2129-H2136, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01399.2007 [Abstract] [Full Text] [PDF]

Yingheng Liu, Rebecca A. Redetzke, Suleman Said, James V. Pottala, Gabriella Morreale de Escobar, and A. Martin Gerdes: Serum thyroid hormone levels may not accurately reflect thyroid tissue levels and cardiac function in mild hypothyroidism
Am J Physiol Heart Circ Physiol 294: H2137-H2143, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01379.2007 [Abstract] [Full Text] [PDF]

Christopher M. Quick, Arun M. Venugopal, Ranjeet M. Dongaonkar, Glen A. Laine, and Randolph H. Stewart: First-order approximation for the pressure-flow relationship of spontaneously contracting lymphangions
Am J Physiol Heart Circ Physiol 294: H2144-H2149, 2008. First published March 7, 2008; doi:10.1152/ajpheart.00781.2007 [Abstract] [Full Text] [PDF]

Ivo R. Henkens, Koen T. B. Mouchaers, Anton Vonk-Noordegraaf, Anco Boonstra, Cees A. Swenne, Arie C. Maan, Sum-Che Man, Jos W. R. Twisk, Ernst E. van der Wall, Martin J. Schalij, and Hubert W. Vliegen: Improved ECG detection of presence and severity of right ventricular pressure load validated with cardiac magnetic resonance imaging
Am J Physiol Heart Circ Physiol 294: H2150-H2157, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01312.2007 [Abstract] [Full Text] [PDF]

Dovenia S. Ponnoth, Ahmed Nadeem, and S. Jamal Mustafa: Adenosine-mediated alteration of vascular reactivity and inflammation in a murine model of asthma
Am J Physiol Heart Circ Physiol 294: H2158-H2165, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01224.2007 [Abstract] [Full Text] [PDF]

Holly D. Bauser-Heaton, Jin Song, and H. Glenn Bohlen: Cerebral microvascular nNOS responds to lowered oxygen tension through a bumetanide-sensitive cotransporter and sodium-calcium exchanger
Am J Physiol Heart Circ Physiol 294: H2166-H2173, 2008. First published March 7, 2008; doi:10.1152/ajpheart.01074.2007 [Abstract] [Full Text] [PDF]

J. Darcy O'Brien, Jessica H. Ferguson, and Susan E. Howlett: Effects of ischemia and reperfusion on isolated ventricular myocytes from young adult and aged Fischer 344 rat hearts
Am J Physiol Heart Circ Physiol 294: H2174-H2183, 2008; doi:10.1152/ajpheart.00058.2008 [Abstract] [Full Text] [PDF]

Afsana Momen, Jian Cui, Patrick McQuillan, and Lawrence I. Sinoway: Local prostaglandin blockade attenuates muscle mechanoreflex-mediated renal vasoconstriction during muscle stretch in humans
Am J Physiol Heart Circ Physiol 294: H2184-H2190, 2008. First published March 7, 2008; doi:10.1152/ajpheart.00948.2007 [Abstract] [Full Text] [PDF]

Hiroshi Watanabe, Seiryo Sugiura, and Toshiaki Hisada: The looped heart does not save energy by maintaining the momentum of blood flowing in the ventricle
Am J Physiol Heart Circ Physiol 294: H2191-H2196, 2008; doi:10.1152/ajpheart.00041.2008 [Abstract] [Full Text] [PDF] [Supplemental Videos]

Tetsuya Hayashi, Chika Yamashita, Chika Matsumoto, Chol-Jun Kwak, Kiwako Fujii, Tomoko Hirata, Masatoshi Miyamura, Tatsuhiko Mori, Akira Ukimura, Yoshikatsu Okada, Yasuo Matsumura, and Yasushi Kitaura: Role of gp91^phox-containing NADPH oxidase in left ventricular remodeling induced by intermittent hypoxic stress
Am J Physiol Heart Circ Physiol 294: H2197-H2203, 2008; doi:10.1152/ajpheart.91496.2007 [Abstract] [Full Text] [PDF]

Ian P. Luttrell, Mei Swee, Barry Starcher, William C. Parks, and Kanchan Chitaley: Erectile dysfunction in the type II diabetic db/db mouse: impaired venoocclusion with altered cavernosal vasoreactivity and matrix
Am J Physiol Heart Circ Physiol 294: H2204-H2211, 2008; doi:10.1152/ajpheart.00027.2008 [Abstract] [Full Text] [PDF]

Yong-Fu Xiao, Daniel C. Sigg, Michael R. Ujhelyi, Joshua J. Wilhelm, Eric S. Richardson, and Paul A. Iaizzo: Pericardial delivery of omega-3 fatty acid: a novel approach to reducing myocardial infarct sizes and arrhythmias
Am J Physiol Heart Circ Physiol 294: H2212-H2218, 2008; doi:10.1152/ajpheart.91502.2007 [Abstract] [Full Text] [PDF]

Sanjay Misra, Alex A. Fu, Alessandra Puggioni, Kamran M. Karimi, Jaywant N. Mandrekar, James F. Glockner, Luis A. Juncos, Bilal Anwer, Antonio M. McGuire, and Debabrata Mukhopadhyay: Increased shear stress with upregulation of VEGF-A and its receptors and MMP-2, MMP-9, and TIMP-1 in venous stenosis of hemodialysis grafts
Am J Physiol Heart Circ Physiol 294: H2219-H2230, 2008. First published March 7, 2008; doi:10.1152/ajpheart.00650.2007 [Abstract] [Full Text] [PDF]

Guangmao Cheng, Michael R. Zile, Masaru Takahashi, Catalin F. Baicu, D. Dirk Bonnema, Fernando Cabral, Donald R. Menick, and George Cooper, 4th: A direct test of the hypothesis that increased microtubule network density contributes to contractile dysfunction of the hypertrophied heart
Am J Physiol Heart Circ Physiol 294: H2231-H2241, 2008; doi:10.1152/ajpheart.91515.2007 [Abstract] [Full Text] [PDF]

Aaron J. Trask, Jewell A. Jessup, Mark C. Chappell, and Carlos M. Ferrario: Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart
Am J Physiol Heart Circ Physiol 294: H2242-H2247, 2008. First published March 21, 2008; doi:10.1152/ajpheart.00175.2008 [Abstract] [Full Text] [PDF]

Nobuo Momoi, Joseph P. Tinney, Li J. Liu, Huda Elshershari, Paul J. Hoffmann, John C. Ralphe, Bradley B. Keller, and Kimimasa Tobita: Modest maternal caffeine exposure affects developing embryonic cardiovascular function and growth
Am J Physiol Heart Circ Physiol 294: H2248-H2256, 2008. First published March 21, 2008; doi:10.1152/ajpheart.91469.2007 [Abstract] [Full Text] [PDF]

Xiongwen Chen, Xiaoying Zhang, David M. Harris, Valentino Piacentino, III, Remus M. Berretta, Kenneth B. Margulies, and Steven R. Houser: Reduced effects of BAY K 8644 on L-type Ca²⁺ current in failing human cardiac myocytes are related to abnormal adrenergic regulation
Am J Physiol Heart Circ Physiol 294: H2257-H2267, 2008. First published March 21, 2008; doi:10.1152/ajpheart.01335.2007 [Abstract] [Full Text] [PDF]

Katheryn Gambetta, Mohamad K. Al-Ahdab, Michel N. Ilbawi, Nahidh Hassaniya, and Madhu Gupta: Transcription repression and blocks in cell cycle progression in hypoplastic left heart syndrome
Am J Physiol Heart Circ Physiol 294: H2268-H2275, 2008; doi:10.1152/ajpheart.91494.2007 [Abstract] [Full Text] [PDF]

Zakar H. Mnjoyan, Dennis Doan, Jimi Lynn Brandon, Kumar Felix, Christy L. Sitter, Ajay A. Rege, Tommy A. Brock, and Ken Fujise: The critical role of the intrinsic VSMC proliferation and death programs in injury-induced neointimal hyperplasia
Am J Physiol Heart Circ Physiol 294: H2276-H2284, 2008; doi:10.1152/ajpheart.91527.2007 [Abstract] [Full Text] [PDF]

Ed W. Childs, Binu Tharakan, Nickolas Byrge, John H. Tinsley, Felicia A. Hunter, and W. Roy Smythe: Angiopoietin-1 inhibits intrinsic apoptotic signaling and vascular hyperpermeability following hemorrhagic shock
Am J Physiol Heart Circ Physiol 294: H2285-H2295, 2008. First published March 14, 2008; doi:10.1152/ajpheart.01361.2007 [Abstract] [Full Text] [PDF]

James P. Fisher, Colin N. Young, and Paul J. Fadel: Effect of muscle metaboreflex activation on carotid-cardiac baroreflex function in humans
Am J Physiol Heart Circ Physiol 294: H2296-H2304, 2008; doi:10.1152/ajpheart.91497.2007 [Abstract] [Full Text] [PDF]

Yu-Jung Chen, Jing Li, and John Quilley: Deficient renal 20-HETE release in the diabetic rat is not the result of oxidative stress
Am J Physiol Heart Circ Physiol 294: H2305-H2312, 2008. First published March 7, 2008; doi:10.1152/ajpheart.00868.2007 [Abstract] [Full Text] [PDF]

Julia Feygin, Qinsong Hu, Cory Swingen, and Jianyi Zhang: Relationships between regional myocardial wall stress and bioenergetics in hearts with left ventricular hypertrophy
Am J Physiol Heart Circ Physiol 294: H2313-H2321, 2008. First published March 7, 2008; doi:10.1152/ajpheart.01288.2007 [Abstract] [Full Text] [PDF]

Masako Yamaoka Endo, Rie Suzuki, Naomi Nagahata, Naoyuki Hayashi, Akira Miura, Shunsaku Koga, and Yoshiyuki Fukuba: Differential arterial blood flow response of splanchnic and renal organs during low-intensity cycling exercise in women
Am J Physiol Heart Circ Physiol 294: H2322-H2326, 2008; doi:10.1152/ajpheart.91491.2007 [Abstract] [Full Text] [PDF]

Guoliang Ding, Rob F. Wiegerinck, Ming Shen, Anca Cojoc, Carlo M. Zeidenweber, and Mary B. Wagner: Dopamine increases L-type calcium current more in newborn than adult rabbit cardiomyocytes via D1 and β₂ receptors
Am J Physiol Heart Circ Physiol 294: H2327-H2335, 2008. First published March 28, 2008; doi:10.1152/ajpheart.00993.2007 [Abstract] [Full Text] [PDF]

Eugene F. du Toit, Wayne Smith, Christo Muller, Hans Strijdom, Bernadette Stouthammer, Angela J. Woodiwiss, Gavin R. Norton, and Amanda Lochner: Myocardial susceptibility to ischemic-reperfusion injury in a prediabetic model of dietary-induced obesity
Am J Physiol Heart Circ Physiol 294: H2336-H2343, 2008. First published March 21, 2008; doi:10.1152/ajpheart.00481.2007 [Abstract] [Full Text] [PDF]

Julie Balch Samora, Jefferson C. Frisbee, and Matthew A. Boegehold: Increased myogenic responsiveness of skeletal muscle arterioles with juvenile growth
Am J Physiol Heart Circ Physiol 294: H2344-H2351, 2008. First published March 28, 2008; doi:10.1152/ajpheart.00053.2008 [Abstract] [Full Text] [PDF]

Andreas A. Werdich, Eduardo A. Lima, Igor Dzhura, Madhu V. Singh, Jingdong Li, Mark E. Anderson, and Franz J. Baudenbacher: Differential effects of phospholamban and Ca²⁺/calmodulin-dependent kinase II on [Ca²⁺]_i transients in cardiac myocytes at physiological stimulation frequencies
Am J Physiol Heart Circ Physiol 294: H2352-H2362, 2008. First published March 21, 2008; doi:10.1152/ajpheart.01398.2006 [Abstract] [Full Text] [PDF]

Emmanuel M. Awumey, Sylvie K. Hill, Debra I. Diz, and Richard D. Bukoski: Cytochrome P-450 metabolites of 2-arachidonoylglycerol play a role in Ca²⁺-induced relaxation of rat mesenteric arteries
Am J Physiol Heart Circ Physiol 294: H2363-H2370, 2008. First published March 28, 2008; doi:10.1152/ajpheart.01042.2007 [Abstract] [Full Text] [PDF]

Gregory M. Dick, Ian N. Bratz, Léna Borbouse, Gregory A. Payne, Ü. Deniz Dincer, Jarrod D. Knudson, Paul A. Rogers, and Johnathan D. Tune: Voltage-dependent K⁺ channels regulate the duration of reactive hyperemia in the canine coronary circulation
Am J Physiol Heart Circ Physiol 294: H2371-H2381, 2008. First published March 28, 2008; doi:10.1152/ajpheart.01279.2007 [Abstract] [Full Text] [PDF]

Sergio de Frutos, Laura Duling, Dominique Alò, Tammy Berry, Olan Jackson-Weaver, Mary Walker, Nancy Kanagy, and Laura González Bosc: NFATc3 is required for intermittent hypoxia-induced hypertension
Am J Physiol Heart Circ Physiol 294: H2382-H2390, 2008. First published March 21, 2008; doi:10.1152/ajpheart.00132.2008 [Abstract] [Full Text] [PDF]

Ka Young Chung, Misuk Kang, and Jeffery W. Walker: Contractile regulation by overexpressed ET_A requires intact T tubules in adult rat ventricular myocytes
Am J Physiol Heart Circ Physiol 294: H2391-H2399, 2008; doi:10.1152/ajpheart.00011.2008 [Abstract] [Full Text] [PDF]

CORRIGENDA:

: Corrigendum
Am J Physiol Heart Circ Physiol 294: H2410-H2410, 2008; doi:10.1152/ajpheart.zh4-8275-corr.2008 [Full Text] [PDF]

REPORTS:

Matthew Kay, Luther Swift, Brian Martell, Ara Arutunyan, and Narine Sarvazyan: Locations of ectopic beats coincide with spatial gradients of NADH in a regional model of low-flow reperfusion
Am J Physiol Heart Circ Physiol 294: H2400-H2405, 2008. First published February 29, 2008; doi:10.1152/ajpheart.01158.2007 [Abstract] [Full Text] [PDF]

Gabriella F. Kocsis, Judit Pipis, Veronika Fekete, Andrea Kovács-Simon, Louise Odendaal, Éva Molnár, Zoltán Giricz, Tamás Janáky, Jacques van Rooyen, Tamás Csont, and Péter Ferdinandy: Lovastatin interferes with the infarct size-limiting effect of ischemic preconditioning and postconditioning in rat hearts
Am J Physiol Heart Circ Physiol 294: H2406-H2409, 2008. First published March 21, 2008; doi:10.1152/ajpheart.00862.2007 [Abstract] [Full Text] [PDF]

Cover Caption:

Cover

Cover: Rotigaptide prevents ischemia-induced dephosphorylation of connexin43 in cardiac gap junctions. Confocal immunofluorescence images show no change in the distribution, pattern, or quantity of Cx43 signal in rotigaptide-treated hearts during ischemia. See Kjølbye AL, Dikshteyn M, Eloff BC, Deschênes I, Rosenbaum DS. Maintenance of intercellular coupling by the antiarrhythmic peptide rotigaptide suppresses arrhythmogenic discordant alternans. Am J Physiol Heart Circ Physiol 294: H41–H49, 2008.