Table 3.

Hemodynamic parameters in infarcted animals

BL (PreBSGS)BSGSBL (PreBMCGS)BMCGS (PreCSD)PreCSDPostCSDBL (PreMCGS PostCSD)BMCGS (PostCSD)
HR, bpm85 ± 10.794 ± 21*84 ± 11.8112 ± 22*§83 ± 1384 ± 1384 ± 13114 ± 24*
dP/dtmax, mmHg/s1,246 ± 3902,127 ± 315*1,123 ± 3322271 ± 9678*984 ± 349880 ± 337878 ± 3381797 ± 937*
dP/dtmin, mmHg/s−1,280 ± 582−1,157 ± 542−1,179 ± 537−1,093 ± 635−1,090 ± 571−1,025 ± 634−1,027 ± 630−958 ± 574
LVESP, mmHg90 ± 20123 ± 2886 ± 2199 ± 21§78 ± 2569 ± 2269 ± 2286 ± 26
  • Values represent mean ± SD % change in parameters from prestimulation value (n = 12). PostCSD values represent hemodynamic parameters after a 30-min period of stabilization after removal of stellate ganglia. PreCSD represents hemodynamic values immediately before removal of the stellate ganglia. HR, heart rate; dP/dtmax, dP/dtmin, maximum and minimum dP/dt; LVESP, left ventricular end-systolic pressure; BSGS, bilateral stellate ganglion stimulation; BMCGS, bilateral middle cervical ganglion stimulation.

  • * P value < 0.05 for % change from baseline (prestimulation).

  • P = 0.06 for % increase in dP/dtmax with BMCGS compared with BSGS.

  • P = 0.02 for comparison of PreCSD vs. PostCSD.

  • § P < 0.01 for comparison of BMCGS vs. BSGS.