Table 5.

By inflammatory cytokine and cytokine receptor gene array analysis, 16 genes were increased and 10 decreased in TG LV

WTTGP
↑ in TG
    Abcf156.86 ± 2.8984.56 ± 4.62<0.0001
    Ccl110.67 ± 0.221.51 ± 0.250.0225
    Ccl121.22 ± 0.434.95 ± 0.730.0003
    Ccl40.32 ± 0.070.62 ± 0.070.0081
    Ccr20.88 ± 0.191.78 ± 0.150.0020
    Ccr30.35 ± 0.061.13 ± 0.13<0.0001
    Ccr50.51 ± 0.202.72 ± 0.40<0.0001
    Cxcr30.17 ± 0.040.38 ± 0.070.0091
    Il10rb65.96 ± 7.93124.36 ± 8.38<0.0001
    Il13ra113.62 ± 1.1318.93 ± 0.780.0021
    Il1522.15 ± 2.0232.81 ± 1.820.0015
    Il2rg8.06 ± 1.0311.67 ± 0.800.0173
    Itgb23.24 ± 0.285.05 ± 0.440.0024
    Mif47.43 ± 6.08145.7 ± 8.48<0.0001
    Scye141.68 ± 4.0476.53 ± 5.54<0.0001
    Tnfrsf1a9.33 ± 0.6214.72 ± 0.67<0.0001
↓ in TG
    C3133.21 ± 11.0690.97 ± 7.940.0093
    Ccl1924.52 ± 4.0311.61 ± 0.870.0205
    Ccl200.048 ± 0.0050.030 ± 0.0040.0193
    Ccr91.44 ± 0.190.72 ± 0.130.0097
    Il181.38 ± 0.210.63 ± 0.070.0044
    Il1r113.59 ± 0.998.10 ± 0.430.0002
    Il101.15 ± 0.270.37 ± 0.080.0155
    Il130.21 ± 0.040.09 ± 0.020.0269
    Il40.23 ± 0.050.08 ± 0.030.0352
    Tgfb141.14 ± 3.5627.54 ± 1.580.0051
  • Data are expressed as means ± SE. Gene expression was normalized to hypoxanthine-guanine phosphoribosyltransferase 1 and shown as 2−ΔCt × 100 units. All genes listed were P < 0.05 vs. WT (WT, n = 10; TG, n = 8). Underlines, proinflammatory genes.