Table 2.

Results of multiple linear regression analysis for all parameters

Phase of Diastole PBPMLPMIPr2
Mechanical diastole
    MDD, ms−549±422.13±0.2461,500±1,8000.98
    VTI, cm10.3±1.30.0732±0.01600.12
E wave
    EDUR, ms313±9−0.957±0.1150.29
    AT, ms116±5−0.335±0.530.18
    DT, ms198±10−0.653±0.1170.16
    Epeak, cm/s96.2±19.1
    Ddiastasis, ms−1,150±120*4.40±0.7765,500±4,4000.89
    Ddiastasis, ms600±23−6.82±0.280.78
A wave
    ADUR, ms166±4−0.454±0.0490.20
    Apeak, cm/s5.05±7.270.661±.0110.32
    Apeak, cm/s−44.7±10.58§1.26±.0110.57
  • Values are means ± SE. P, parameter; BP, parameter intercept; MLP, linear heart rate (HR) dependence coefficient; MIP, inverse HR dependence coefficient; MDD, mechanical diastolic duration; VTI, velocity time integral; EDUR, E wave duration; AT, acceleration time; DT, deceleration time; Epeak, peak E-wave velocity; Ddiastasis, duration of diastasis; ADUR, duration of A wave; Apeak, peak A-wave velocity. To account for inverse HR dependence a regression of the algebraic form of Eq. 2 was used. All others were fit using a linear relation P = BP + MLP × HR, except Epeak. All results were statistically significant (P < 0.01).

  • * Nonlinear fit of the form in Eq. 2;

  • linear fit;

  • Ddiastasis > 0;

  • § Ddiastasis < 0. See text for details.