Table 5.

Vascular studies and exercise performance in vitamin C trial

Before CVAfter CV
Group 1Group 2Group 3Group 1Group 2Group 3
ControlVit CControlVit CControlVit CControlVit CControlVit CControlVit C
Vascular studies
Brachial artery FMD
    mm0.26±0.010.31±0.020.27±0.020.30±0.010.28±0.010.27±0.020.36±0.02*0.35±0.01*0.32±0.02*0.31±0.020.26±0.020.25±0.02
    %7.2±0.510.8±0.47.4±0.69.1±0.37.1±0.76.9±0.712.9±0.6*12.7±0.6*10.2±0.4*10.4±0.46.9±0.76.7±0.7
Reactive hyperemia, ml/min245±15256±18256±13263±16269±17278±22293±14*278±20*276±16*261±21257±18264±19
Δ brachial artery diameter/Δflow, mm·ml−1·min−1×1,0001.06±0.21.21±011.05±0.31.14±0.21.04±0.20.97±0.31.22±0.2*1.25±0.11.18±0.2*1.16±0.31.01±0.30.94±0.3
Exercise performance
Peak workload, W114±22125±16100±25114±1497±2095±20135±18*137±23*117±20*118±22100±23103±18
Peak V̇o2, ml·kg−1·min−116±318±215±417±214±614±820±4*20±318±3*19±4§16±516±7
Group 1Group 2Group 3Group 1Group 2Group 3
ControlPlaceboControlPlaceboControlPlaceboControlPlaceboControlPlaceboControlPlacebo
Vascular studies
Brachial artery FMD
    mm0.25±0.010.26±0.020.24±0.010.23±0.010.26±0.010.25±0.020.34±0.01*0.35±0.02*0.31±0.02*0.30±0.01*0.27±0.020.27±0.01
    %7.3±0.67.4±0.77.1±0.87.0±0.57.2±0.87.1±0.612.1±0.5*12.5±0.7*9.8±0.6*10.1±0.5*6.9±0.56.7±0.7
Reactive hyperemia, ml/min234±17230±19246±15250±21254±20261±15287±15*294±18*280±20276±22264±22253±16
Δ brachial artery diameter/Δflow, mm·ml−1·min−1×1,0001.06±011.13±0.30.93±0.10.92±0.21.02±0.20.95±0.31.18±0.1*1.19±0.9*1.10±0.1*1.08±0.1*1.02±0.21.06±0.3
Exercise performance
Peak workload, W117±25118±19109±24106±2892±2096±22138±16*136±17*128±16*131±19*98±2694±23
Peak V̇o2, ml·kg−1·min−115±216±715±315±214±514±619±3*19±5*17±2*17±2*15±414±4
  • Values are means ± SD (n = 4).

  • * P < 0.05 vs. before CV.

  • P < 0.05 vs. control.