Table 3.

Conventional and PDF parameters/indexes of longitudinal diastolic function

Parameter/IndexMAO+ Group (n = 35)MAO Group (n = 20)Intergroup Significance
E′, cm/s17.5 (3.1)13.5 (3.9)P < 0.00001
AT′, ms65 (12)54 (11)P < 0.01
DT′, ms79 (17)67 (20)P < 0.05
VTIE′, mm12.7 (3.5)8.3 (3.7)P < 0.0001
VTIE′ − VTIE″, mm*10.4 (3.6)8.3 (3.7)P < 0.05
A′, cm/s16.3 (3.6)15.5 (3.5)P = 0.42
VTIA′, mm7.3 (2.3)8.6 (3.0)P = 0.06
E′/A′1.11 (0.28)0.91 (0.35)P < 0.05
E/E′4.16 (1.15)5.18 (1.80)P < 0.05
c′, g/s18.3 (5.9)48.6 (7.7)P < 0.00001
k′, g/s1490 (120)594 (233)P < 0.05
xo, cm1.16 (0.32)0.85 (0.45)P < 0.01
kxo, dyn547 (153)460 (149)P < 0.05
Embedded Imagekxo′2, erg337 (164)217 (147)P < 0.01
β′, s−2−1,787 (489)0 (0)P < 0.00001
  • Values are means (SD). E′ and A′, peak amplitude of E′ and A′ wave, respectively; AT′ and DT′, acceleration and deceleration time of E′ wave, respectively; VTIE′ and VTIE″, velocity-time integral of E′ and E″ wave, respectively; VTIA′, velocity-time integral of A′ wave; E, peak amplitude of E wave; c′, longitudinal damping constant; k′, longitudinal spring constant; (xo), initial longitudinal displacement of spring before release; β′, effect of longitudinal stiffness vs. relaxation.

  • * E″ waves were absent in subjects without annular oscillations.

  • β′ was computed for the MAO subjects by assuming critical damping as discussed in methods. Bold type indicates significance.