Table 4.

Indexes of longitudinal LV diastolic function derived from Doppler tissue imaging of the septal aspect of the mitral annulus

nBaseline1 yr%ChangeP Value, Within-Group ChangeP Value, Between-Groups Change
E′, cm/s
    CR88 (SD 1)10 (SD 1)17.3 (SD 11.2)0.0020.10
    Ex98 (SD 1)9 (SD 1)5.5 (SD 14.6)0.35
A′, cm/s
    CR810 (SD 2)11 (SD 2)5.7 (SD 23.5)0.800.64
    Ex911 (SD 2)11 (SD 2)2.0 (SD 11.6)0.66
E′/A′
    CR80.8 (SD 0.2)0.9 (SD 0.2)16.1 (SD 28.0)0.150.29
    Ex90.8 (SD 0.1)0.8 (SD 0.2)5.4 (SD 22.3)0.63
E/E′
    CR89.7 (SD 3.9)8.0 (SD 2.5)−13.0 (SD 17.3)0.040.52
    Ex98.9 (SD 1.8)8.0 (SD 1.9)−8.0 (SD 22.6)0.21
c′, g/s
    CR820.5 (SD 5.7)22.2 (SD 6.3)17.3 (SD 54.7)0.590.63
    Ex918.0 (SD 2.5)20.9 (SD 5.0)18.0 (SD 31.2)0.20
k′, g/s2
    CR8263 (SD 37)324 (SD 37)25.7 (SD 24.6)0.020.13
    Ex9283 (SD 42)286 (SD 53)3.1 (SD 24.2)0.87
xo, cm
    CR80.9 (SD 0.1)1.1 (SD 0.1)15.3 (SD 13.3)0.010.93
    Ex90.9 (SD 0.1)1.1 (SD 0.1)13.8 (SD 14.0)0.02
kxo, g·cm/s2
    CR8244 (SD 45)343 (SD 55)45.5 (SD 38.6)0.010.17
    Ex9264 (SD 45)302 (SD 51)16.9 (SD 28.1)0.13
1/2kxo2, g·cm2/s2
    CR8116 (SD 32)186 (SD 43)71.4 (SD 60.6)0.010.23
    Ex9127 (SD 31)162 (SD 36)33.5 (SD 38.8)0.04
  • Values are means (SD); n, number of subjects. PDF parameters and computed indexes were not determined for 1 subject in the CR and 1 subject in the Ex group due to inadequate image quality.