Table 5.

LV morphology and indexes of systolic function

nBaseline1 yr%ChangeP Value, Within-Group ChangeP Value, Between-Groups Change
IVS, mm
    CR129 (SD 2)9 (SD 3)0.1 (SD 18.1)0.970.15
    Ex119 (SD 1)8 (SD 1)−9.5 (SD 11.8)0.01
LVEDD, mm
    CR1249 (SD 5)51 (SD 4)5.0 (SD 9.0)0.080.55
    Ex1150 (SD 6)51 (SD 7)2.4 (SD 5.0)0.15
LVESD, mm
    CR1230 (SD 4)31 (SD 3)5.3 (SD 12.5)0.240.61*
    Ex1131 (SD 5)31 (SD 6)2.0 (SD 10.5)0.60
PW, mm
    CR128 (SD 1)8 (SD 1)1.7 (SD 17.3)0.940.93
    Ex119 (SD 2)8 (SD 1)−4.6 (SD 19.8)0.29
FS, %
    CR1239 (SD 4)39 (SD 4)0.6 (SD 9.9)1.000.97
    Ex1139 (SD 5)39 (SD 5)1.7 (SD 12.6)0.76
LVEDV, ml
    CR12108 (SD 23)118 (SD 20)11.1 (SD 19.6)0.070.64
    Ex11112 (SD 24)118 (SD 31)5.2 (SD 10.4)0.15
LVESV, ml
    CR1233 (SD 10)36 (SD 7)12.7 (SD 27.4)0.280.57*
    Ex1136 (SD 12)37 (SD 14)4.7 (SD 20.8)0.57
SV, ml
    CR1275 (SD 14)82 (SD 15)11.1 (SD 19.4)0.060.61
    Ex1176 (SD 15)81 (SD 19)6.0 (SD 10.1)0.09
  • Values are means (SD); n, number of subjects. Two subjects in the Ex group were not analyzed due to technical difficulties in acquiring M-mode images for these subjects. IVS, interventricular septum thickness; LVEDD, LV end-diastolic diameter; LVESD, LV end-systolic diameter; PW, posterior wall thickness; FS, fractional shortening; LVEDV, LV end-diastolic volume; LVESV, LV end-systolic volume; SV, stroke volume.

  • * P value based on ANCOVA using ranks of the raw data.