Table 1.

Interspecies comparison of mice and NMRs: observed values and their relative percentage of values predicted allometrically

%Predicted Value
MouseNMRSignificanceMouseNMR
Body mass, g26.1 ± 1.345.6 ± 3.30.0002
Heart mass, mg130 ± 10190 ± 100.00048068
Heart:body mass, %0.50 ± 0.020.41 ± 0.030.007
Nonanesthetized heart rate, beats/min704 ± 11256 ± 8<0.000113557
Cardiac output, ml/min14.9 ± 0.76.5 ± 0.4<0.000114943
  • All values are means ± SE. NMR, naked mole-rat. Sample sizes are n = 10 (5/sex) for each species. Significance is indicated by P values. The following equations were used for predicted values, where Mb denotes body mass: heart mass, 0.0058 Mb(kg)0.98 × 1000000 (32); heart rate, 10−0.251 log Mb(g) + 3.072 (5); and cardiac output, 187 Mb(kg)0.81 (36).